About atm

Manuscript Submission

AME Editing Service

Reprint & Permission

Advertising

Contact us

Endorsement

Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.

Endorsement
Endorsement
Endorsement

the Brazilian Society of Thoracic Surgery(SBCT)

the Brazilian Society of Thoracic Surgery(SBCT) the Bonnie J. Addario Lung Cancer Foundation (ALCF)

Original Article

Effect of a medicinal and edible decoction YH0618 on chemotherapy-induced dermatologic toxicity: a randomized controlled trial
Jieshu You, Yanhua He, Hui Zhi, Victor Hofun Lee, Suetmui Chan, Lixing Lao, Huanlan Liu, Jianping Chen
Dual inhibition of RNAi therapeutic miR-26a-5p targeting cMet and immunotherapy against EGFR in endometrial cancer treatment
Yun Liu, Yixuan Cai, Yue Chang
Real-world results of the implementation of preoperative anaemia clinic with intravenous iron therapy for treating iron-deficiency anaemia: a propensity-matched case-control study
Hairil R. Abdullah, Tanakorn Thamnachit, Ying Hao, Wan Yen Lim, Li Ming Teo, Yilin Eileen Sim
What is the optimal number of neoadjuvant chemotherapy cycles for resectable colorectal liver oligometastases?
Qichen Chen, Xingchen Li, Jianjun Zhao, Xinyu Bi, Zhiyu Li, Zhen Huang, Yefan Zhang, Jianguo Zhou, Hong Zhao, Jianqiang Cai
Short-term dietary restriction ameliorates brain injury after cardiac arrest by modulation of mitochondrial biogenesis and energy metabolism in rats
Minggen Zhou, Tao Yu, Xiangshao Fang, Qiulin Ge, Fengqing Song, Zitong Huang, Longyuan Jiang, Peng Wang
Endometrial cavity fluid is associated with deleterious pregnancy outcomes in patients undergoing in vitro fertilization/intracytoplasmic sperm injection: a retrospective cohort study
Wen-Xiu Zhang, Lian-Bao Cao, Ying Zhao, Jing Li, Bo-Feng Li, Jia-Nan Lv, Lei Yan, Jin-Long Ma
Effect of liver injury on prognosis and treatment of hospitalized patients with COVID-19 pneumonia
Guo-Guang Ma, Ya-Xing Shen, Ling Wu, Zhe Luo, Chou-Wen Zhu, Shi-Yao Chen, Kai-Huan Yu, Feng Li
Prognostic factors for pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome: a multicenter study in China
Haitao Shang, Tao Bai, Shenghua Zhu, Xiaoqian Yang, Chang Liu, Dong Xu, Yuzheng Zhuge, Yuhu Song, Xiaohua Hou
Nomograms based on clinicopathological factors and inflammatory indicators for prediction of early and late recurrence of hepatocellular carcinoma after surgical resection for patients with chronic hepatitis B
Tianxing Dai, Mingbin Deng, Linsen Ye, Guozhen Lin, Rongqiang Liu, Yinan Deng, Rong Li, Wei Liu, Hua Li, Yang Yang, Guihua Chen, Guoying Wang
Characteristics and clinical subtypes of cancer patients in the intensive care unit: a retrospective observational study for two large databases
Shaowei Gao, Yaqing Wang, Lu Yang, Zhongxing Wang, Wenqi Huang
A STING-related prognostic score predicts high-risk patients of colorectal cancer and provides insights into immunotherapy
Si-Yuan Chen, Siyu Chen, Wanjing Feng, Ziteng Li, Yixiao Luo, Xiaodong Zhu
Incidence and prognosis of undifferentiated cancers of the digestive system: a population-based cohort study
Jingping Qiu, Yan Xin
Clinical results and complications associated with oblique lumbar interbody fusion technique
Cheng Cheng, Kai Wang, Can Zhang, Hao Wu, Fengzeng Jian
High serum gamma-glutamyl transpeptidase concentration associates with poor postoperative prognosis of patients with hepatitis B virus-associated intrahepatic cholangiocarcinoma
Bo Zhang, Shuang Liu, Binghai Zhou, Lei Guo, Hui Li, Jiuliang Yan, Wentao Zhang, Mincheng Yu, Zheng Chen, Yongfeng Xu, Yongsheng Xiao, Qinghai Ye
Inhibition of laser induced rats choroidal neovascularization by intravitreous injection of sEphB4-HSA
Shikun He, Sha Ouyang, Xiaohua Li, Binyun Ma
The trend of indirect anastomosis formation in a 2-vessel occlusion plus encephalo-myo-synangiosis rat model
Wensheng Li, Lei Wei, Bocheng Wang, Shuangqi Gao, Tengchao Huang, Zhangyu Li, Robin Bhattarai, Hui Wang, Ying Guo, Chuan Chen
The effect of 1.9-mm versus 2.4-mm probes in transbronchial cryobiopsies for interstitial lung diseases: a prospective analysis
Guowu Zhou, Yanhong Ren, Jun Li, Ting Yang, Nan Su, Ling Zhao, Shumeng Wang, Dan Wang, Ying Li, Zheng Tian, Ruihong Liu, Huaping Dai, Chen Wang
Computed tomography-measured bone mineral density as a surrogate marker of survival after resection of colorectal liver metastases
Shinichi Ikuta, Tsukasa Aihara, Takayoshi Nakajima, Meidai Kasai, Naoki Yamanaka
Association between comorbid diabetes mellitus and prognosis of patients with sepsis in the intensive care unit: a retrospective cohort study
Shan Lin, Shanhui Ge, Wanmei He, Mian Zeng
Rapid, accurate, multifunctional and self-assisted vision assessment and screening with interactive desktop autostereoscopy
Xiaoke Li, Jing Zhong, Yiyao Wang, Hantao Zhang, Jinrong Li, Kunyang Li, Li Gu, Min Zheng, Jin Yuan, Hang Fan, Dongyan Deng, Yao Wang, Jianying Zhou
Additional chemotherapy improves survival in stage II–III pulmonary sarcomatoid carcinoma patients undergoing surgery: a propensity scoring matching analysis
Yanhong Cen, Chunxu Yang, Jiangbo Ren, Yan Gong, Conghua Xie
Poor consistency between reflux symptom index and laryngopharyngeal pH monitoring in laryngopharyngeal reflux diagnosis in Chinese population
Jun-Yao Wang, Tao Peng, Li-Li Zhao, Gui-Jian Feng, Yu-Lan Liu
Elevated lipoprotein(a) and risk of coronary heart disease according to different lipid profiles in the general Chinese community population: the CHCN-BTH study
Chunyue Guo, Han Cao, Guangliang Shan, Wei Zhao, Han Zhang, Kaijun Niu, Ze Cui, Naijun Tang, Kuo Liu, Li Pan, Xiaoyan Han, Zhengfang Wang, Ge Meng, Jixin Sun, Anqi Shan, Yuxiang Yan, Huijing He, Zhiyuan Xu, Yajing Cao, Wenjuan Peng, Yanyan Sun, Yunyi Xie, Xiaohui Liu, Bingxiao Li, Fuyuan Wen, Ling Zhang
Survey on uric acid in Chinese subjects with essential hypertension (SUCCESS): a nationwide cross-sectional study
Jing Liu, Luyuan Chen, Hong Yuan, Kai Huang, Guangping Li, Ningling Sun, Yong Huo, on behalf of the SUCCESS investigation group
Higher plasma NT-proBNP levels correlate with syndrome of inappropriate antidiuretic hormone and poor prognosis in neurological patients
Qing-Ling Zeng, Wen-Tao He, Gang Yuan
Macrophage-derived netrin-1 contributes to endometriosis- associated pain
Shaojie Ding, Xinyue Guo, Libo Zhu, Jianzhang Wang, Tiantian Li, Qin Yu, Xinmei Zhang
No diffuse intrahepatic biliary stricture after ABO-incompatible adult living donor liver transplantation using tailored rituximab-based desensitization protocol
Koji Natsuda, Takahiro Murokawa, Kwang-Woong Lee, Kyung Chul Yoon, Suk Kyun Hong, Jeong-Moo Lee, Jae-Hyung Cho, Nam-Joon Yi, Kyung-Suk Suh
Primary tumor surgery improves survival of cancer patients with synchronous solitary bone metastasis: a large population-based study
Wei Wu, Honghua Zhang, Zhong Fang, Feng Li
Identification of a novel interplay between intestinal bacteria and metabolites in Chinese patients with IgA nephropathy via integrated microbiome and metabolome approaches
Hongwei Wu, Donge Tang, Fengping Zheng, Shanshan Li, Xinzhou Zhang, Lianghong Yin, Fanna Liu, Yong Dai
Plasma cytokines interleukin-18 and C-X-C motif chemokine ligand 10 are indicative of the anti-programmed cell death protein-1 treatment response in lung cancer patients
Yida Wang, Hanxiao Chen, Tianzhuo Zhang, Xue Yang, Jia Zhong, Yuyan Wang, Yujia Chi, Meina Wu, Tongtong An, Jianjie Li, Xinghui Zhao, Zhi Dong, Ziping Wang, Jun Zhao, Minglei Zhuo, Jing Huang
Efficacy of immune-checkpoint inhibitors in advanced non-small cell lung cancer patients with different metastases
Meng Qiao, Fei Zhou, Likun Hou, Xuefei Li, Chao Zhao, Tao Jiang, Guanghui Gao, Chunxia Su, Chunyan Wu, Shengxiang Ren, Caicun Zhou
Anthropometric parameters and liver histology influence lipid metabolic changes in HCV chronic hepatitis on direct-acting antiviral treatment
Domenico Iossa, Martina Vitrone, Massimo Gagliardi, Erasmo Falco, Enrico Ragone, Rosa Zampino, Emanuele Durante-Mangoni
Multispectral optoacoustic tomography of peripheral arterial disease based on muscle hemoglobin gradients—a pilot clinical study
Angelos Karlas, Max Masthoff, Michael Kallmayer, Anne Helfen, Michail Bariotakis, Nikolina Alexia Fasoula, Michael Schäfers, Max Seidensticker, Hans-Henning Eckstein, Vasilis Ntziachristos, Moritz Wildgruber
Predicting aggressive histopathological features in esophageal cancer with positron emission tomography using a deep convolutional neural network
Joe Chao-Yuan Yeh, Wei-Hsiang Yu, Cheng-Kun Yang, Ling-I Chien, Ko-Han Lin, Wen-Sheng Huang, Po-Kuei Hsu
miR-126-3p contributes to sorafenib resistance in hepatocellular carcinoma via downregulating SPRED1
Wenliang Tan, Zhirong Lin, Xianqing Chen, Wenxin Li, Sicong Zhu, Yingcheng Wei, Liyun Huo, Yajin Chen, Changzhen Shang
Surface-treated 3D printed Ti-6Al-4V scaffolds with enhanced bone regeneration performance: an in vivo study
Guangdao Zhang, Pengyu Zhao, Lin Lin, Limei Qin, Zhiguang Huan, Sander Leeflang, Amir A. Zadpoor, Jie Zhou, Lin Wu
Bone mineral density, osteopenia, osteoporosis, and fracture risk in patients with atopic dermatitis: a systematic review and meta- analysis
Di Wu, Xiang-Dong Wu, Xi Zhou, Wei Huang, Changqi Luo, Yong Liu
Predictive factors of postoperative pancreatic fistula after laparoscopic pancreatoduodenectomy
Jikuan Jin, Guangbing Xiong, Jiali Li, Xingjun Guo, Min Wang, Zhen Li, Feng Zhu, Renyi Qin
CMTM8 as an LPA1-associated partner mediates lysophosphatidic acid-induced pancreatic cancer metastasis
Weidong Shi, Chenyue Zhang, Zhouyu Ning, Yongqiang Hua, Ye Li, Lianyu Chen, Luming Liu, Zhen Chen, Zhiqiang Meng
Automatic prediction of treatment outcomes in patients with diabetic macular edema using ensemble machine learning
Baoyi Liu, Bin Zhang, Yijun Hu, Dan Cao, Dawei Yang, Qiaowei Wu, Yu Hu, Jingwen Yang, Qingsheng Peng, Manqing Huang, Pingting Zhong, Xinran Dong, Songfu Feng, Tao Li, Haotian Lin, Hongmin Cai, Xiaohong Yang, Honghua Yu
Clinical findings in a group of COVID-19 patients: a single-center retrospective study
Fang Ji, Liang Wang, Chunyang Li, Liping Wang, Jungui Hao, Mingjia Dai, Yan Liu, Xiucheng Pan, Juanjuan Fu, Li Li, Guangde Yang, Jianye Yang, Xiao Zhang, Jiachuan Wang, Renhao Wang, Xuebing Yan, Bing Gu
Roles of NANOGP8 in cancer metastasis and cancer stem cell invasion during development of castration-resistant prostate cancer
Yi Sui, Wei Zhang, Rujian Zhu, Lili Gao, Ting Cao, Chuhong Chen, Min Gong, Hongbo Zhu, Tao Tang, Bo Yu, Tao Yang
Diagnosis and management of protracted bacterial bronchitis: a survey of Chinese pediatricians
Qinyuan Li, Ziyao Guo, Yuanyuan Li, Guangli Zhang, Xiaoyin Tian, Ruixue Gu, Zhengxiu Luo
Caveolin-1 promotes radioresistance via IRGM-regulated autophagy in lung cancer
Xi Chen, Yuan-Liang Yan, Shuang-Shuang Zeng, Zhi-Cheng Gong, Zhi-Jie Xu
Risk factors of regional lymph node (RLN) metastasis among patients with bone sarcoma and survival of patients with RLN-positive bone sarcoma
Yimin Dong, Wei Wu, Honglei Kang, Wei Xiong, Dawei Ye, Zhong Fang, Hanfeng Guan, Hui Liao, Feng Li
Impact of anesthesia methods on perioperative systemic inflammation and long-term outcomes in patients undergoing surgery for hepatocellular carcinoma: a propensity score-matched analysis
Hao Zhang, Kefang Guo, Xingfeng Sun, Yi Liu, Ziwen Zhong, Wenchang Zhou, Weian Zeng, Lu Wang, Juan P. Cata, Wankun Chen, Changhong Miao
Endoscopic ultrasound efficacy in staging gastric linitis plastica lesion: a retrospective multicentric French study
Stephanie Morgant, Pascal Artru, Ammar Oudjit, Nelson Lourenco, Arnaud Pasquer, Thomas Walter, Jean-Marc Gornet, Alexandre Rouquette, Catherine Brezault, Romain Coriat
A multi-center study of prediction of macular hole status after vitrectomy and internal limiting membrane peeling by a deep learning model
Yijun Hu, Yu Xiao, Wuxiu Quan, Bin Zhang, Yuqing Wu, Qiaowei Wu, Baoyi Liu, Xiaomin Zeng, Ying Fang, Yu Hu, Songfu Feng, Ling Yuan, Tao Li, Hongmin Cai, Honghua Yu
Identification of crucial genes mediating abdominal aortic aneurysm pathogenesis based on gene expression profiling of perivascular adipose tissue by WGCNA
Siliang Chen, Dan Yang, Bao Liu, Yuexin Chen, We Ye, Mengyin Chen, Yuehong Zheng
Sex-specific survival benefit in early skin melanoma based on 8th AJCC edition: an analysis of data from the Surveillance, Epidemiology, and End Results (SEER) database
Ran Mo, Chen Chen, Yanan Jiang, Zhouji Ma, Xueyong Meng, Qian Tan
A novel prognostic nomogram for patients with surgically resected perihilar cholangiocarcinoma: a SEER-based study
Pengfei Li, Lujun Song
Hepatobiliary phase hypointensity on gadobenate dimeglumine- enhanced magnetic resonance imaging may improve the diagnosis of hepatocellular carcinoma
Yueming Li, Jianwei Chen, Shuping Weng, Chuan Yan, Rongping Ye, Yuemin Zhu, Liting Wen, Dairong Cao, Jinsheng Hong
The predictive prognostic values of serum interleukin-2, interleukin-6, interleukin-8, tumor necrosis factor-α, and procalcitonin in surgical intensive care unit patients
Yamin Yan, Yan Hu, Xiaorong Wang, Zhenghong Yu, Yingjia Tang, Yuxia Zhang, Wenyan Pan
The effects of TGF-β1 on staphylococcus epidermidis biofilm formation in a tree shrew biomaterial-centered infection model
Yujie Lei, Yushan Xu, Peng Jing, Bingquan Xiang, Keda Che, Junting Shen, Minjie Ning, Ying Chen, Yunchao Huang
Profiles of alternative splicing landscape in breast cancer and their clinical significance: an integrative analysis based on large-sequencing data
Jun-Xian Du, Yong-Lei Liu, Gui-Qi Zhu, Yi-Hong Luo, Cong Chen, Cheng-Zhe Cai, Si-Jia Zhang, Biao Wang, Jia-Liang Cai, Jian Zhou, Jia Fan, Zhi Dai, Wei Zhu
N6-methyladenosine (m6A)-mediated messenger RNA signatures and the tumor immune microenvironment can predict the prognosis of hepatocellular carcinoma
Shen Shen, Jingya Yan, Yize Zhang, Zihui Dong, Jiyuan Xing, Yuting He
Quadrangular resection versus chordal replacement for degenerative posterior mitral leaflet prolapse
Jiexu Ma, Jian Liu, Peijian Wei, Ximeng Yao, Yuyuan Zhang, Liangzheng Fang, Zhao Chen, Yanjun Liu, Tong Tan, Hongxiang Wu, Huanlei Huang, Bin Xie, Jimei Chen, Jian Zhuang, Huiming Guo
Incision and flap design during total auricular reconstruction using a 2-stage strategy
Yangxue Ou, Tongyu Cao, Qingguo Zhang, Tun Liu
Clinical manifestations of blood cell parameters and inflammatory factors in 92 patients with COVID-19
Rongrong Deng, Changzheng Wang, Yi Ye, Liyao Gou, Zhongxiao Fu, Bo Ye, Feng Shao, Xiaomei Zhang, Weiyang Fu, Jianping Xiao, Tao Li, Huan Qi, Chengbin Li
Temporal dynamic changes of intrinsic brain activity in Alzheimer’s disease and mild cognitive impairment patients: a resting-state functional magnetic resonance imaging study
Ting Li, Zhengluan Liao, Yanping Mao, Jiaojiao Hu, Dansheng Le, Yangliu Pei, Wangdi Sun, Jixin Lin, Yaju Qiu, Junpeng Zhu, Yan Chen, Chang Qi, Xiangming Ye, Heng Su, Enyan Yu
EEG power spectral analysis reveals tandospirone improves anxiety symptoms in patients with Alzheimer’s disease: a prospective cohort study
Zhengluan Liao, Xiaoyu Zhao, Ting Li, Yanping Mao, Jiaojiao Hu, Dansheng Le, Yangliu Pei, Yan Chen, Yaju Qiu, Junpeng Zhu, Jixin Lin, Heng Su, Linju Zhang, Enyan Yu
Disrupted balance of long and short-range functional connectivity density in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) patients: a resting-state fMRI study
Yanping Mao, Zhengluan Liao, Xiaozheng Liu, Ting Li, Jiaojiao Hu, Dansheng Le, Yangliu Pei, Wangdi Sun, Jixin Lin, Yaju Qiu, Junpeng Zhu, Yan Chen, Chang Qi, Heng Su, Enyan Yu

Review Article

A narrative review of the roles of the miR-15/107 family in heart disease: lessons and prospects for heart disease
Manni Zheng, Min Wang
A narrative review of machine learning as promising revolution in clinical practice of scoliosis
Kai Chen, Xiao Zhai, Kaiqiang Sun, Haojue Wang, Changwei Yang, Ming Li
A narrative review of central nervous system involvement in acute leukemias
Dalma Deak, Nicolae Gorcea-Andronic, Valentina Sas, Patric Teodorescu, Catalin Constantinescu, Sabina Iluta, Sergiu Pasca, Ionut Hotea, Cristina Turcas, Vlad Moisoiu, Alina-Andreea Zimta, Simona Galdean, Jakob Steinheber, Ioana Rus, Sebastian Rauch, Cedric Richlitzki, Raluca Munteanu, Ancuta Jurj, Bobe Petrushev, Cristina Selicean, Mirela Marian, Olga Soritau, Alexandra Andries, Andrei Roman, Delia Dima, Alina Tanase, Olafur Sigurjonsson, Ciprian Tomuleasa
A narrative review of acute pancreatitis and its diagnosis, pathogenetic mechanism, and management
Zhi Zheng, Yi-Xuan Ding, Yuan-Xu Qu, Feng Cao, Fei Li
Stem cell secretome, regeneration, and clinical translation: a narrative review
Chukwuweike Gwam, Nequesha Mohammed, Xue Ma
The reliability of adductor tubercle as an anatomical landmark for joint line restoration in revision knee arthroplasty: a systematic review
Berardo Di Matteo, Daniele Altomare, Andrea Dorotei, Giovanni Francesco Raspugli, Tommaso Bonanzinga, Maurilio Marcacci, Elizaveta Kon, Francesco Iacono
A narrative review of risk factors and interventions for cancer- related cognitive impairment
Lu Bai, Enyan Yu

Study Protocol

A phase III study on neoadjuvant chemotherapy versus neoadjuvant toripalimab plus chemotherapy for locally advanced esophageal squamous cell carcinoma: Henan Cancer Hospital Thoracic Oncology Group 1909 (HCHTOG1909)
Yan Zheng, Xian-Ben Liu, Hai-Bo Sun, Jinliang Xu, Sining Shen, Yu-Feng Ba, Ming Yan, Zimin Qin, Bao-Xing Liu, Zong-Fei Wang, Shi-Lei Liu, Rui-Xiang Zhang, Pei-Nan Chen, Guang-Hui Liang, Dongfeng Yuan, Zhen-Xuan Li, Qi Liu, Hao-Ran Wang, Hao-Miao Li, Hongwei Lv, Xiaochao Ma, Jianping Zhu, Yong-Kui Yu, Wen-Qun Xing, written on Henan Cancer Hospital Thoracic Oncology Group (HCHTOG)

iMDT Corner1

Pulmonary angiosarcoma presenting with diffuse alveolar hemorrhage: a case report
Min Yu, Weibin Huang, Yan Wang, Guangsuo Wang, Lingwei Wang, Weihua Tao, Saadia A. Faiz, Fung Him Ng, Huiping Li

Case Report

A rare case of an unexpected difficult airway management in a diffuse idiopathic skeletal hyperostosis patient and post-operative airway evaluation with 3D printing technique
Xiaoqing Zhang, Jun Wang, Yajie Liu, Zhengqian Li, Bin Han
Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report
Carolina Dagli-Hernandez, Renata Caroline Costa de Freitas, Elisangela da Silva Rodrigues Marçal, Rodrigo Marques Gonçalves, Andre Arpad Faludi, Jéssica Bassani Borges, Gisele Medeiros Bastos, Bruna Los, Augusto Akira Mori, Raul Hernandes Bortolin, Glaucio Monteiro Ferreira, Victor Fernandes de Oliveira, Thiago Dominguez Crespo Hirata, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata
A rare case of primary pulmonary inflammatory pseudotumor-like follicular dendritic cell sarcoma successfully treated by lobectomy
Huayu He, Qi Xue, Fengwei Tan, Lin Yang, Xin Wang, Yushun Gao, Yousheng Mao, Juwei Mu, Dali Wang, Jun Zhao, Liang Zhao, Shugeng Gao
A case report of membranous occlusion of the subclavian vein: a rare cause of McCleery syndrome
Jingjing Yin, Zhenhong Qi, Yu Chen, Yuexin Chen
Atypical hemolytic uremic syndrome after childbirth: a case report
Hong Sang Choi, Jae Won Yun, Hee-Jin Kim, Doyeun Oh, Nah Ihm Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
The emergence of various genetic alterations mediated the Osimertinib resistance of a patient harboring heterozygous germline EGFR T790M: a case report
Bin Liu, Jianwen Qin, Yan Yin, Liang Zhai, Guangxin Liu, Analyn Lizaso, Dongsheng Shi
Changes in cognitive function and related brain regions in chronic benzene poisoning: a case report
Jiaojiao Hu, Enyan Yu, Zhengluan Liao

Editorial on Current State of Intraoperative Imaging2

Editorial for current state of intraoperative imaging in spinal surgery
Sheeraz Qureshi

Review Article on Current State of Intraoperative Imaging2

Intraoperative risks of radiation exposure for the surgeon and patient
Nathaniel W. Jenkins, James M. Parrish, Evan D. Sheha, Kern Singh
Current state of navigation in spine surgery
Nathaniel Rawicki, James E. Dowdell, Harvinder S. Sandhu
The current state of navigation in robotic spine surgery
Meng Huang, Tyler A. Tetreault, Avani Vaishnav, Philip J. York, Blake N. Staub
Preoperative planning for intraoperative navigation guidance
Shahbaaz A. Sabri, Philip J. York
Narrative review of intraoperative imaging guidance for decompression-only surgery
Sohrab Virk, Sheeraz Qureshi
Narrative review of intraoperative image guidance for transforaminal lumbar interbody fusion
Joseph A. Weiner, Michael H. McCarthy, Peter Swiatek, Philip K. Louie, Sheeraz A. Qureshi
Intraoperative image guidance for lateral position surgery
Peter R. Swiatek, Michael H. McCarthy, Joseph Weiner, Shivani Bhargava, Avani S. Vaishnav, Sravisht Iyer
Intraoperative image guidance for the surgical treatment of adult spinal deformity
Venkat Boddapati, Joseph M. Lombardi, Hikari Urakawa, Ronald A. Lehman
Intraoperative image guidance for endoscopic spine surgery
Jason I. Liounakos, Gregory W. Basil, Hikari Urakawa, Michael Y. Wang
Intraoperative image guidance for cervical spine surgery
Sertac Kirnaz, Harry Gebhard, Taylor Wong, Raj Nangunoori, Franziska Anna Schmidt, Kosuke Sato, Roger Härtl
Current innovation in virtual and augmented reality in spine surgery
Frank J. Yuk, Georgios A. Maragkos, Kosuke Sato, Jeremy Steinberger

Disclosure:

1. The series “iMDT Corner” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

2. The series “Current State of Intraoperative Imaging” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding. Sheeraz Qureshi served as the unpaid Guest Editor for the series.

Case Report

Laparoscopic Roux-en-Y duodenojejunostomy for annular pancreas in adults: case report and literature review
He Cai, Xin Wang, Yun-Qiang Cai, Yong-Bin Li, Ling-Wei Meng, Bing Peng
Laparoscopic pancreaticoduodenectomy with major venous resection and reconstruction with repassed round ligament: a case report
Yunqiang Cai, Yongbin Li, Pan Gao, Xin Wang, Bing Peng
Metastatic colorectal cancer in a cirrhotic liver with synchronous hepatocellular carcinoma
Michael Karass, Emily Grossniklaus, Talal Seoud, Ralph Kamel, Oluwadamilola Teniola, Gabriela Oprea, Daniel A. Goldstein, Sanjay Jain

Editorial

Translating L-2-HG to kidney cancer at the bench and bedside
Omran Abu Aboud, Robert H. Weiss
Vascular Deformation Mapping (VDM) of thoracic aortic aneurysm: an application for color 3D printing in aortic disease
Nicholas S. Burris, Benjamin A. Hoff, Brian D. Ross
Dasatinib in breast cancer: Src-ing for response in all the wrong kinases
Laura C. Kennedy, Vijayakrishna Gadi
Cardiac troponin I—more than a biomarker for myocardial ischemia?
Li Ni, Xander H. T. Wehrens
Ifi204/p204, a new piece in the sepsis puzzle
Gayatri Subramanian, Ritu Chakravarti, Saurabh Chattopadhyay
Fusion heals the broken-hearted
Daniel A. Zuppo, Michael Tsang
Adjuvant antiviral therapy for the prevention of hepatocellular carcinoma recurrence after liver resection: indicated for all patients with chronic hepatitis B?
Clifford Akateh, Timothy M. Pawlik, Jordan M. Cloyd
Acidosis and citrate: provocative interactions
Kathleen S. Hering-Smith, L. Lee Hamm
Protecting functional β cells with a therapeutic peptide
Meghan L. Marré, Jon D. Piganelli, Eddie A. James
The Art of War and oncology: applying the principles of strategy and tactics to greater effect in the era of targeted therapy
Emil Lou
Protease activated receptor 4: a backup receptor or a dark horse as a target in antiplatelet therapy?
Xu Han, Marvin T. Nieman
Geospatial modelling in guiding health program strategies in resource-limited settings—the way forward
Diane Gu, Chawangwa Modongo, Sanghyuk S. Shin, Nicola M. Zetola
Surrogate end points in early prostate cancer clinical states: ready for implementation?
Christos E. Kyriakopoulos, Emmanuel S. Antonarakis
Profiling of plasma-derived extracellular vesicles cargo for diagnosis of pancreatic malignancy
Theresa L. Whiteside
Evolving treatment options for valve and aortic disease with bicuspid aortic valve
Nicholas S. Burris, Michael D. Hope
Exosomes may play a crucial role in HIV dendritic cell immunotherapy
Benjamin Wolfson, Justine E. Yu, Qun Zhou
Custom cutting guides in total knee arthroplasty
Morad Chughtai, Anton Khlopas, Iyooh U. Davidson, George A. Yakubek, Kim L. Stearns, Michael A. Mont
Dendritic cell-derived exosomes for cancer immunotherapy: hope and challenges
Hong Tian, Wei Li
It takes time to tune
Brandon S. Bentzley, Jaspreet Pannu, Bashar W. Badran, Casey H. Halpern, Nolan R. Williams
Intra-luminal focused ultrasound for augmentation of gastrointestinal drug delivery
Ezekiel Maloney, Joo Ha Hwang
Re-assessing stem cells in the stomach—one story two tales
Ming Jiang, Jianwen Que
Extracellular vesicles isolation and their biomarker potential: are we ready for testing?
Theresa L. Whiteside
One size doesn’t fit all: unraveling the diversity of factors and interactions that drive E. coli urovirulence
Henry L. Schreiber IV, Caitlin N. Spaulding, Karen W. Dodson, Jonathan Livny, Scott J. Hultgren
Defensin-chemokine heteromeric complexes derived from heterocellular activation—a possible target to inhibit CCL5 in cardiovascular settings
Osamu Baba, Yongjian Liu, Gwendalyn J Randolph
An effective DNA vaccine platform for Middle East respiratory syndrome coronavirus
Adam S Cockrel, Ralph S Baric
Can multispectral optoacoustic tomography replace sentinel lymph biopsy in melanoma?
Stanley P. L. Leong, Sri-Rajasekhar Kothapalli, Sanjiv Sam Gambhir
The evolving approach to sedation in ventilated patients: a real world perspective
Annachiara Marra, Pratik P. Pandharipande
From static to dynamic: a sepsis-specific dynamic model from clinical criteria in polytrauma patients
Rami A. Namas, Yoram Vodovotz
Do insights from mice imply that combined Th2 and Th17 therapies would benefit select severe asthma patients?
Matthew E. Poynter
Re-assessing the role of non-fasting lipids; a change in perspective
Zareen Farukhi, Samia Mora
Narcolepsy and influenza vaccination—the inappropriate awakening of immunity
Anoma Nellore, Troy D. Randall
A canine model for neuronal ceroid lipofuscinosis highlights the promise of gene therapy for lysosomal storage diseases
Jonathan E. Phillips, Richard H. Gomer
Connecting enterovirus infection to dystrophin dysfunction in dilated cardiomyopathy
Qiongling Wang, Xander H. T. Wehrens
The AMPK-SKP2-CARM1 axis links nutrient sensing to transcriptional and epigenetic regulation of autophagy
Ziheng Xu, Daniel J. Klionsky
Is the regulation of SIRT1 by miRNA-34a the key to mesenchymal stem cell survival?
Michael A. Bellio, Wayne Balkan, Joshua M. Hare, Ivonne Hernandez Schulman
Getting to the core of fibrosis: targeting redox imbalance in aging
Louise Hecker, Victor J. Thannickal
Radiotherapy: killing with complement
Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming
Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy
Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli
Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?
Sarina Bains, Prasad S. Adusumilli
Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome
Irfana Muqbil, Ramzi M. Mohammad
Microbiome, a new dimension in cancer research
Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei
The CRISPR road: from bench to bedside on an RNA-guided path
Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
γδ T cells and immunity to human malaria in endemic regions
Samarchith P. Kurup, John T. Harty
Apyrase as a novel therapeutic inhibitor of heterotopic ossification
Olin D. Liang, Anthony M. Reginato, Damian Medici
The coming of age of adoptive T-cell therapy for viral infection after stem cell transplantation
Austin John Barrett, Catherine M. Bollard
Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized
Mark R. Walter
Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?
Kevin P. Daly
Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era
Kimberly J. Payne, Abigail Benitez, Sinisa Dovat
Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?
Jayoung Kim, Wun-Jae Kim

Editorial Commentary

Glycosylation of natriuretic peptides in obese heart failure: mechanistic insights
Vibhu Parcha, Pankaj Arora
Pluripotential stem cells as replacement therapy in degenerative diseases of the eye
Colin J. Barnstable
Reactive astrocytes foster brain metastases via STAT3 signaling
Braden C. McFarland, Etty N. Benveniste
Cryo-electron microscopy reveals informative details of GABAA receptor structural pharmacology: implications for drug discovery
Richard W. Olsen, A. Kerstin Lindemeyer, Martin Wallner, Xiaorun Li, Kevin W. Huynh, Z. Hong Zhou
‘RNA circles of influence’ in Kaposi sarcoma
Dimitrios Tsitsipatis, Myriam Gorospe
A novel macrophage subtype directs hematopoietic stem cell homing and retention
Marcin Wysoczynski, Joseph B. Moore IV, Shizuka Uchida
Profiling changes in metabolism and the immune microenvironment in lung tumorigenesis
Di Zhang, Ana S. Leal, Fawzi Abu Rous, Karen T. Liby
Lessons learned by features of pancreatic ductal adenocarcinoma and its tumor microenvironment
Alex B. Blair, Vincent P. Groot, Jin He
Nephron repair: powered by anaerobic energy metabolism
Brooke E. Chambers, Rebecca A. Wingert
Blocking the PD-1/PD-L1 axis in advanced prostate cancer: are we moving in the right direction?
Andre P. Fay, Emmanuel S. Antonarakis
Strengthening the foundation of kidney cancer treatment and research: revising the AJCC staging system
Hiren V. Patel, Arnav Srivastava, Brian Shinder, Evita Sadimin, Eric A. Singer
Revisiting AJCC TNM staging for renal cell carcinoma: quest for improvement
Umang Swami, Roberto H. Nussenzveig, Benjamin Haaland, Neeraj Agarwal

Letter to the Editor

Challenges to interpreting patient reported outcomes in clinical trials: author rejoinder
Melanie L. Bell
Low levels of interleukin-10 in patients with transfusion-related acute lung injury
Rick Kapur, Michael Kim, Johan Rebetz, Matthew T. Rondina, Leendert Porcelijn, John W. Semple
Circulating CD40 autoantibody and suPAR synergy drives glomerular injury
Changli Wei, Tara K. Sigdel, Minnie M. Sarwal, Jochen Reiser
Gene replacement rescues severe muscle pathology and prolongs survival in myotubularin-deficient mice and dogs
Martin K. Childers, Alan H. Beggs, Ana Buj-Bello

Original Article

GLI1 is increased in ovarian endometriosis and regulates migration, invasion and proliferation of human endometrial stromal cells in endometriosis
Hengwei Liu, Wei Zhang, Lili Wang, Zhibing Zhang, Wenqian Xiong, Ling Zhang, Tian Fu, Xiaoou Li, Yaobing Chen, Yi Liu
Genome-wide association study of cerebrospinal fluid neurofilament light levels in non-demented elders
Li-Dong Niu, Wei Xu, Jie-Qiong Li, Chen-Chen Tan, Xi-Peng Cao, Jintai Yu, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative
Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress in vitro
Yoram Vodovotz, Richard L. Simmons, Derek Barclay, Jinling Yin, Bahiyyah S. Jefferson, Ruben Zamora
Altering cough reflex sensitivity with aerosolized capsaicin paired with behavioral cough suppression: a proof-of-concept study
Laurie J. Slovarp, Emma Bozarth
Prevalent osteoporotic vertebral fractures more likely involve the upper endplate than the lower endplate and even more so in males
Nazmi Che-Nordin, Min Deng, James F. Griffith, Jason C. S. Leung, Anthony W. L. Kwok, Yue-Qi Zhu, Richard H. Y. So, Timothy C. Y. Kwok, Ping Chung Leung, Yì Xiáng J. Wáng
Genome-wide association study identifies RBFOX1 locus influencing brain glucose metabolism
Ling-Li Kong, Dan Miao, Lin Tan, Shu-Lei Liu, Jie-Qiong Li, Xi-Peng Cao, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative
ABCA7 genotype altered Aβ levels in cerebrospinal fluid in Alzheimer’s disease without dementia
Fang-Chen Ma, Yu Zong, Hui-Fu Wang, Jie-Qiong Li, Xi-Peng Cao, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative
Impact factors of orthopaedic journals between 2010 and 2016: trends and comparisons with other surgical specialties
Nequesha S. Mohamed, Chukwuweike U. Gwam, Jennifer I. Etcheson, Nicole E. George, Nicolas S. Piuzzi, Samuel Rosas, Nipun Sohdi, Assem A. Sultan, Anton Khlopas, Ronald E. Delanois
Impact of smoking in patients undergoing transcatheter aortic valve replacement
Manyoo Agarwal, Sahil Agrawal, Lohit Garg, Guy L. Reed, Rami N. Khouzam, Uzoma N. Ibebuogu
Impact of family history of coronary artery disease on in-hospital clinical outcomes in ST-segment myocardial infarction
Manyoo A. Agarwal, Lohit Garg, Carl J. Lavie, Guy L. Reed, Rami N. Khouzam
National use of total hip arthroplasty among patients with a history of breast, lung, prostate, colon or bladder cancer—an analysis of the Medicare population
Samuel Rosas, Karim Sabeh, Jennifer Kurowicki, Leonard Buller, Tsun Yee Law, Martin Roche, Sheila Conway, Victor H. Hernandez
Prospective study of quality of life after lung cancer resection
Kathleen G. Hopkins, Peter F. Ferson, Manisha R. Shende, Neil A. Christie, Matthew J. Schuchert, Arjun Pennathur
Probiotics for prevention of urinary stones
John C. Lieske
Variations in mRNA and protein levels of Ikaros family members in pediatric T cell acute lymphoblastic leukemia
Julie L. Mitchell, Thomas M. Yankee
Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers
Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari

Review Article

Emerging biomarkers in autism spectrum disorder: a systematic review
Richard E. Frye, Sarah Vassall, Gurjot Kaur, Christina Lewis, Mohammand Karim, Daniel Rossignol
Pompe disease gene therapy: neural manifestations require consideration of CNS directed therapy
Barry J. Byrne, David D. Fuller, Barbara K. Smith, Nathalie Clement, Kirsten Coleman, Brian Cleaver, Lauren Vaught, Darin J. Falk, Angela McCall, Manuela Corti
Liver depot gene therapy for Pompe disease
Priya S. Kishnani, Dwight D. Koeberl
Genetics and epigenetic factors of Wilson disease
Valentina Medici, Janine M. LaSalle
Ventilator-induced lung injury and lung mechanics
Jason H. T. Bates, Bradford J. Smith
Precision oncology in liver cancer
Kevin M. Sullivan, Heidi L. Kenerson, Venu G. Pillarisetty, Kimberly J. Riehle, Raymond S. Yeung
Emerging application of genomics-guided therapeutics in personalized lung cancer treatment
Aubhishek Zaman, Trever G. Bivona
Aminoquinoline antimalarial therapy in dermatomyositis—are we missing opportunities with respect to comorbidities and modulation of extracutaneous disease activity?
Richard D. Sontheimer
Surveillance versus esophagectomy in esophageal cancer patients with a clinical complete response after induction chemoradiation
Tara R. Semenkovich, Bryan F. Meyers
Inhalation therapies in acute respiratory distress syndrome
Antonio Artigas, Marta Camprubí-Rimblas, Neus Tantinyà, Josep Bringué, Raquel Guillamat-Prats, Michael A. Matthay
The female urinary microbiota, urinary health and common urinary disorders
Linda Brubaker, Alan J. Wolfe
The association between bacteria and urinary stones
Andrew L. Schwaderer, Alan J. Wolfe
PDX1 associated therapy in translational medicine
Juehua Yu, Shi-He Liu, Robbi Sanchez, John Nemunaitis, Enrique Rozengurt, F. Charles Brunicardi
Biomarkers of risk to develop lung cancer in the new screening era
Thomas Atwater, Pierre P. Massion
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly
Update in genetic susceptibility in melanoma
Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig

Column in Changemakers in Patient-Oriented Translational Clinical Investigation

James Neil Gilliam, MD—the career arc of a patient-oriented translational clinical investigation changemaker in rheumatologic skin disease
Richard D. Sontheimer

Technical Note

Laparoscopic suture training curricula and techniques
Xin Wang, Yongbin Li, Yunqiang Cai, Lingwei Meng, He Cai, Xubao Liu, Bing Peng

Commentary

Vinculin at the heart of aging
William H. Bradford, Jeffrey H. Omens, Farah Sheikh
MET signaling promotes DNA repair and radiation resistance in glioblastoma stem-like cells
Pavlina Krasimirova Todorova, Bipasha Mukherjee, Sandeep Burma
Uncovering the influence of the FGFR1 pathway on glioblastoma radiosensitivity
Karen K. Sayal, Geoffrey S. Higgins, Ester M. Hammond
Epigenetic therapy in a new era of medicine: creating and integrating molecular profiles of patients
Ebrahim Afshinnekoo, Christopher E. Mason
Patellar resurfacing after endoprosthetic replacement for primary or secondary bone tumors
Alexander D. Liddle
A sensible approach to targeting STAT3-mediated transcription
Neil E. Bhola, Daniel E. Johnson, Jennifer R. Grandis
Circulating fibrocytes serve as a marker for clinical diagnosis
Thuy Cao, Sheeja Rajasingh, Johnson Rajasingh
Collagen and fibronectin: threads linking obesity and breast cancer
Lesley G. Ellies
Abrupt versus gradual smoking cessation with pre-cessation nicotine replacement therapy for cigarette smokers motivated to quit
Elias M. Klemperer, Karl O. Fagerstrom, John R. Hughes
Quantification of lung recruitment by respiratory mechanics and CT imaging: what are the clinical implications?
Andrew C. McKown, Lorraine B. Ware
TGFβ signaling: a friend or a foe to hepatic fibrosis and tumorigenesis
Dragana Kopanja, Pradip Raychaudhuri
Applications of iPSC-derived models of Gaucher disease
Daniel K. Borger, Elma Aflaki, Ellen Sidransky
Significance of microRNA-based biomarkers for pancreatic cancer
Sukhwinder Kaur, Shiv Ram Krishn, Satyanarayana Rachagani, Surinder K. Batra

Health Service and Policy Research

Health Services & Policy Research in translational medicine
Nengliang (Aaron) Yao

Editorials

Circulating free DNA in the management of breast cancer
Jacqueline A. Shaw, Justin Stebbing

Review Articles

The physiological roles of secretin and its receptor
Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser
Effect of high fat-diet and obesity on gastrointestinal motility
Mazen Al Mushref, Shanthi Srinivasan
Functional role of microvesicles in gastrointestinal malignancies
Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds
Noorjahan Panjwani

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test
Takahiro Uotani, David Y. Graham

Health Service and Policy Research Column

Diabetes management before and after cancer diagnosis: missed opportunity
Nengliang Yao, Fabian T. Camacho, Askar S. Chukmaitov, Steven T. Fleming, Roger T. Anderson
The real difficulty in improving concordance of clinical practice with guidelines
Nengliang Yao, Abram Recht

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease
Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease
David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease
Christiane Reitz

Review Article on Innovations and Technology in Surgery

Surgical applications of three-dimensional printing: a review of the current literature & how to get started
Don Hoang, David Perrault, Milan Stevanovic, Alidad Ghiassi

Review Article on MET as Actionable Target in Cancer Therapy

MET: roles in epithelial-mesenchymal transition and cancer stemness
Hye-Min Jeon, Jeongwu Lee
Effective implementation of novel MET pharmacodynamic assays in translational studies
Apurva K. Srivastava, Tony Navas, William G. Herrick, Melinda G. Hollingshead, Donald P. Bottaro, James H. Doroshow, Ralph E. Parchment

Perspective on Mesothelioma

Novel immunotherapy clinical trials in malignant pleural mesothelioma
Zachary E. Tano, Navin K. Chintala, Xiaoyu Li, Prasad S. Adusumilli

Review Article on Mesothelioma

Mesothelioma: recent highlights
Michele Carbone, Haining Yang
Environmental asbestos exposure and risk of mesothelioma
Curtis W. Noonan

Original Article on Translational Neurodegeneration

The impact of GAB2 genetic variations on cerebrospinal fluid markers in Alzheimer’s disease
Xiao-Xiao Chen, Run-Rong Guo, Xi-Peng Cao, Lin Tan, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative

Review Article on Molecular Hepatology

Fibroblast growth factors 19 and 21 in acute liver damage
Zhao Shan, Gloria Alvarez-Sola, Iker Uriarte, María Arechederra, Maite G. Fernández-Barrena, Carmen Berasain, Cynthia Ju, Matías A. Avila

Editorial on Cardiovascular Disease and Cardiometabolic Risk: Advances in Understanding Pathophysiology, Public Health Burden and Clinical Care

Advances in resistant hypertension
David A. Calhoun

Review Article on Cardiopulmonary Interactions

Heart-lung interactions during mechanical ventilation: the basics
Syed S. Mahmood, Michael R. Pinsky

Review Article on Inborn Errors of Metabolism

Congenital disorders of glycosylation
Irene J. Chang, Miao He, Christina T. Lam

Review Article on Health and Medicine: a new era

Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy
Sachin Kumar Deshmukh, Sanjeev Kumar Srivastava, Teja Poosarla, Donna Lynn Dyess, Nicolette Paolaungthong Holliday, Ajay Pratap Singh, Seema Singh

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.

Case Report


Editorial


Original Article


Review Article


Consensus

2020 expert consensus statement on neuro-protection after cardiac arrest in China
Qingbian Ma, Liqun Feng, Tao Wang, Yongqiu Li, Zhenzhong Li, Bin Zhao, Xiuchuan Qin, Qingxi Li, Shizheng Wu, Hongbin Sun, Jun Yuan, Lan Chu, Jian Wu, Yuxiang Gu, Peter Pang, Zhi Chen, Dongsheng Fan, on behalf of the Brain and Vascular Branch & First Aid and Resuscitation Branch of the Chinese Society of Cardiothoracic and Vascular Anaesthesiology