Vol 8, No 7 (April 2020): Annals of Translational Medicine

Editorial

The potential for microRNA-based therapeutics in retinal disorders
Joshua A. Chu-Tan, Riccardo Natoli
The potential of glioma-associated oncogene homolog 1 (GLI1) as a therapeutic target in endometriosis
Konstantinos Nirgianakis, Marc Spaanderman, Boris W. Kramer, Martin Mueller
Use of patient-reported data in determining factors contributing to internal jugular vein stenosis outcomes
Dejan Jakimovski, Robert Zivadinov
Preemptive kidney support: an optimal practice or a good theory?
Zaccaria Ricci, Fiorenza Ferrari, Stefano Romagnoli
Uniportal video-assisted thoracoscopic surgery using an intra-muscle closure during removal of drain
Kazuhito Funai
A novel suture technique in closing the single drainage tube hole in uni-portal video-assisted thoracoscopic surgery
Terumoto Koike, Seijiro Sato, Masanori Tsuchida
When is the optimal timing of frozen embryo transfer after controlled ovarian stimulation?
Hyun Joo Lee, Jong Kil Joo
A “Parasite” in bronchiectasis and COPD research
Joan B. Soriano, Rosa Girón
Usefulness of the mass screening program for colorectal cancer in China: further long-term validation is needed to confirm its value
Whi-An Kwon, Ho Kyung Seo
Risk of suicide among adolescents and young adults with cancer and a need for targeted interventions
Saki Harashima, Maiko Fujimori

Expert Consensus

Chinese expert brief consensus on newborn screening of inherited metabolic disorders during the novel coronavirus infection epidemic
Shan Liu, Dongjuan Wang, Kexing Wan, Hao Liu, Dayong Zhang, Jing Yang, Zhaojian Yuan, Xiaoyan He, Jie Wang, Mingcai Ou, Wenbin Zhu, Yiping Qu, Dehua Zhao, Weipeng Wang, Shiguo Liu, Maosheng Gu, Shuodan Huang, Zhiguo Wang, Lin Zou

Original Article

The effect of RAS blockers on the clinical characteristics of COVID-19 patients with hypertension
Zheyong Huang, Jiatian Cao, Yumeng Yao, Xuejuan Jin, Zhe Luo, Yuan Xue, Chouwen Zhu, Yanan Song, Ying Wang, Yunzeng Zou, Juying Qian, Kaihuan Yu, Hui Gong, Junbo Ge
Laparoscopic versus open hemihepatectomy: a 1:1 matched analysis
Yifan Wang, Jing Fang, Liumei Lin, Long Pan, Junjie Nan, Xinhua Cui, Hui Liu, Mingyu Chen, Qiuxia Gu, Xiujun Cai
An algorithm for one-stage malignant oncologic scalp reconstruction
Yuqiu Zhou, Zhenhua Jiang, Chao Li, Yongcong Cai, Ronghao Sun, Chunyan Shui, Changming An, Zhengqi Tang, Jianfeng Sheng, Dingrong Liu, Dingfen Zeng, Jian Jiang, Guiquan Zhu, Shaoxin Wang
MicroRNA-18a induces epithelial-mesenchymal transition like cancer stem cell phenotype via regulating RKIP pathway in pancreatic cancer
Honggang Kang, Dan Ma, Jing Zhang, Jun Zhao, Mengxiang Yang
A novel machine learning algorithm to predict disease free survival after resection of hepatocellular carcinoma
Markus Bo Schoenberg, Julian Nikolaus Bucher, Dominik Koch, Nikolaus Börner, Sebastian Hesse, Enrico Narciso De Toni, Max Seidensticker, Martin Kurt Angele, Christoph Klein, Alexandr V. Bazhin, Jens Werner, Markus Otto Guba
Ultrasonographic appearance of triple-negative invasive breast carcinoma is associated with novel molecular subtypes based on transcriptomic analysis
Jia-Wei Li, Na Li, Yi-Zhou Jiang, Yi-Rong Liu, Zhao-Ting Shi, Cai Chang, Zhi-Ming Shao
Comparison of functional and volumetric increase of the future remnant liver and postoperative outcomes after portal vein embolization and complete or partial associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
Fadi Rassam, Pim B. Olthof, Krijn P. van Lienden, Roel J. Bennink, Joris I. Erdmann, Rutger-Jan Swijnenburg, Olivier R. Busch, Marc G. Besselink, Thomas M. van Gulik
TRIB3 rs6037475 is a potential biomarker for predicting felodipine drug response in Chinese patients with hypertension
Fazhong He, Bao Sun, Ling Li, Mouze Liu, Weijie Lin, Lin Liu, Yinxiang Sun, Yuhong Luo, Lin Wu, Ligong Lu, Wei Zhang, Zhiling Zhou
Effectiveness and safety of benralizumab for severe asthma in clinical practice (J-BEST): a prospective study
Takehiro Izumo, Mari Tone, Naoyuki Kuse, Nobuyasu Awano, Atsuko Tanaka, Tatsunori Jo, Hanako Yoshimura, Jonsu Minami, Kohei Takada, Minoru Inomata
Surgical procedures including carotid-carotid crossover bypass and ring-stripping hybrid operation for Rile’s type 1A common carotid artery occlusion: an experience of 6 cases
Zhang-Yu Li, Chuan Chen, Cong Ling, Hai-Yong He, Lun Luo, Hao Li, Hui Wang
Quantum biology in low level light therapy: death of a dogma
Andrei P. Sommer, Peter Schemmer, Attila E. Pavláth, Horst-Dieter Försterling, Ádám R. Mester, Mario A. Trelles
Preoperative leukocytosis is associated with increased tumor-infiltrating neutrophil extracellular traps and worse outcomes in esophageal cancer
Hao Zhang, Hu Lv, Meilin Weng, Huihui Wang, Juan P. Cata, Wankun Chen, Changhong Miao
The effect of 6-gingerol on inflammatory response and Th17/Treg balance in DSS-induced ulcerative colitis mice
Yingyue Sheng, Tielong Wu, Yuanyuan Dai, Ke Ji, Yao Zhong, Yuzheng Xue
Clinical characteristics of Coronavirus Disease 2019 and development of a prediction model for prolonged hospital length of stay
Yucai Hong, Xinhu Wu, Jijing Qu, Yuandi Gao, Hao Chen, Zhongheng Zhang
Risk factors for cardiovascular disease from a population-based screening study in Tianjin, China: a cohort study of 36,215 residents
Yingyi Zhang, Hongliang Cong, Chen Man, Yu Su, Hongxia Sun, Hua Yang, Zhigang Guo
Objective secondhand smoke exposure in chronic obstructive pulmonary disease patients without active smoking: the U.S. National Health and Nutrition Examination Survey (NHANES) 2007–2012
Zhen Fu, Hongwei Jiang, Zhongyu Xu, Hongyu Li, Nanjin Wu, Ping Yin
Novel tumor mutation score versus tumor mutation burden in predicting survival after immunotherapy in pan-cancer patients from the MSK-IMPACT cohort
Yuan Li, Zuhua Chen, Long Wu, Weiping Tao
MicroRNA-34a deficiency leads to impaired wound closure by augmented inflammation in mice
Na Zhao, Guojian Wang, Shuang Long, Mengjia Hu, Jining Gao, Xinze Ran, Junping Wang, Yongping Su, Tao Wang
Imitation dynamics in the mitigation of the novel coronavirus disease (COVID-19) outbreak in Wuhan, China from 2019 to 2020
Shi Zhao, Lewi Stone, Daozhou Gao, Salihu S. Musa, Marc K. C. Chong, Daihai He, Maggie H. Wang
Development and trend in the field of valvular heart disease in China: an analysis based on the National Natural Science Foundation of China
Shuyu Wen, Weihua Qiao, Yuan Zhang, Nianguo Dong
Deep learning for detecting corona virus disease 2019 (COVID-19) on high-resolution computed tomography: a pilot study
Shuyi Yang, Longquan Jiang, Zhuoqun Cao, Liya Wang, Jiawang Cao, Rui Feng, Zhiyong Zhang, Xiangyang Xue, Yuxin Shi, Fei Shan
IntegrinB5 upregulated by HER2 in gastric cancer: a promising biomarker for liver metastasis
Qian Li, Ke Peng, Erbao Chen, Huiqin Jiang, Yan Wang, Shan Yu, Wei Li, Yiyi Yu, Tianshu Liu
Distinct secretion pattern of serum proinsulin in different types of diabetes
Yue Tong, Lin Yang, Feng Shao, Xiang Yan, Xia Li, Gan Huang, Yang Xiao, Zhiguang Zhou
Identification of a six-gene signature associated with tumor mutation burden for predicting prognosis in patients with invasive breast carcinoma
Feiran Wang, Chong Tang, Xuesong Gao, Junfei Xu
Timing for removing prophylactic drains after liver resection: an evaluation of drain removal on the third and first postoperative days
Akihiko Ichida, Yoshiharu Kono, Masumitsu Sato, Nobuhisa Akamatsu, Junichi Kaneko, Junichi Arita, Yoshihiro Sakamoto, Norihiro Kokudo, Kiyoshi Hasegawa
New peptidendrocins and anticancer chartreusin from an endophytic bacterium of Dendrobium officinale
Huimin Zhao, Xiabin Chen, Xiaoling Chen, Youjuan Zhu, Yichao Kong, Sifang Zhang, Xingyu Deng, Pengfei Ouyang, Wei Zhang, Shurong Hou, Xiachang Wang, Tian Xie
Two-dimensional speckle tracking echocardiography detected interventricular dyssynchrony predicts exercise capacity and disease severity in pre-capillary pulmonary hypertension
Bing-Yang Liu, Wei-Chun Wu, Qi-Xian Zeng, Zhi-Hong Liu, Li-Li Niu, Yue Tian, Xiao-Ling Cheng, Qin Luo, Zhi-Hui Zhao, Li Huang, Hao Wang, Jian-Guo He, Chang-Ming Xiong
Statistical analysis plan for aggressive hydraTion in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention to prevenT contrast-induced nephropathy (ATTEMPT) study
Jin Liu, Zhaodong Guo, Li Lei, Guoli Sun, Yibo He, Feier Song, Jiyan Chen, Ning Tan, Shiqun Chen, Yong Liu
The effect of blood lactate and NT-proBNP predict the survival in patients with invasive mechanical ventilation
Xiao-Jun Deng, Yan Zou, Jun Wu, Yan Liang, Shui-Yi Gu
Sam68 promotes aerobic glycolysis in colorectal cancer by regulating PKM2 alternative splicing
Jing Zhao, Jiuming Li, Waseem Hassan, Dongyan Xu, Xue Wang, Zhaohui Huang
The analysis of risk for peptic ulcer disease using Korean national health and nutrition examination survey: a cross-sectional analysis of a national survey sample
Kwang Yeol Paik, Hye Eun Seok, Jae Hee Chung
Aspirin use and endometrial cancer risk: a meta-analysis and systematic review
Yang Wang, Junda Zhao, Xing Chen, Feifei Zhang, Xin Li
Increased the risk of heart failure and comorbidities in patients with gout treatment: a population-based cohort study
Hsin-Hung Chen, Ming-Chia Hsieh, Chun-Wei Ho, Ching-Chu Chen, Sheng-Pang Hsu, Shih-Sheng Chang, Cheng-Li Lin, Chia-Hung Kao
Is a simplified TNM staging system more clinically relevant than the American Joint Committee on Cancer system for the follicular variant of papillary thyroid cancer?
Di Hu, Yueye Huang, Wen Zeng, Sichao Chen, Yihui Huang, Man Li, Wei Long, Jianglong Huang, Wei Wei, Chao Zhang, Zeming Liu, Liang Guo
Relationship between body mass index and the risk of periprosthetic joint infection after primary total hip arthroplasty and total knee arthroplasty
Junlong Zhong, Bin Wang, Yufeng Chen, Huizi Li, Nan Lin, Xianghe Xu, Huading Lu
Cell adhesion molecule 2 (CADM2) promotes brain metastasis by inducing epithelial-mesenchymal transition (EMT) in human non-small cell lung cancer
Lu Dai, Jian Zhao, Jun Yin, Wenfan Fu, Gang Chen
High RPS11 level in hepatocellular carcinoma associates with poor prognosis after curative resection
Chenhao Zhou, Jialei Sun, Zhiyuan Zheng, Jialei Weng, Manar Atyah, Qiang Zhou, Wanyong Chen, Yuan Zhang, Jiaxing Huang, Yirui Yin, Huarong Mao, Ziping Zhang, Yong Yi, Ning Ren
Heart transplantation in 47 children: single-center experience from China
Fei Li, Yixuan Wang, Yongfeng Sun, Jing Zhang, Ping Li, Nianguo Dong
The difference of distance stereoacuity measured with different separating methods
Lingzhi Zhao, Yu Zhang, Huang Wu, Jun Xiao
A CT-based radiomics signature for evaluating tumor infiltrating Treg cells and outcome prediction of gastric cancer
Xujie Gao, Tingting Ma, Shuai Bai, Ying Liu, Yuwei Zhang, Yupeng Wu, Hui Li, Zhaoxiang Ye
A new method for predicting survival in stage I non-small cell lung cancer patients: nomogram based on macrophage immunoscore, TNM stage and lymphocyte-to-monocyte ratio
Jiani Gao, Yijiu Ren, Haoyue Guo, Rui Mao, Huikang Xie, Hang Su, Yunlang She, Jiajun Deng, Minglei Yang, Biao Han, Yu Zhang, Jian Li, Dong Xie, Chang Chen
Poststroke Parkinsonism associates with an increased mortality risk in patients
Dorji Harnod, Tomor Harnod, Cheng-Li Lin, Chung Y. Hsu, Chia-Hung Kao
Reduction of FoxP3+ Tregs by an immunosuppressive protocol of rapamycin plus Thymalfasin and Huaier extract predicts positive survival benefits in a rat model of hepatocellular carcinoma
Lin Zhou, Li-Chao Pan, Yong-Gen Zheng, Xin-Xue Zhang, Zhi-Jia Liu, Xuan Meng, Hai-Da Shi, Guo-Sheng Du, Qiang He
Effects of epidural combined with general anesthesia versus general anesthesia alone in gastric cancer surgery: a propensity score matching analysis
Jun-Peng Pei, Chun-Dong Zhang, Yu Liang, Cheng Zhang, Kun-Zhe Wu, Zhe-Ming Zhao, Dong-Qiu Dai
Interaction between delivery mode and maternal age in predicting overweight and obesity in 1,123 Chinese preschool children
Shufang Liu, Jieping Lei, Jia Ma, Yanyan Ma, Shunan Wang, Yuan Yuan, Yu Shang, Zhixin Zhang, Wenquan Niu
Comprehensive management of breast augmentation with polyacrylamide hydrogel injection based on 15 years of experience: a report on 325 cases
Bei Qian, Lingyun Xiong, Ke Guo, Rongrong Wang, Jie Yang, Zhenxing Wang, Jing Tong, Jiaming Sun
Phenotype changes of subchondral plate osteoblasts based on a rat model of ovariectomy-induced osteoarthritis
Ai Jiang, Shan Gao, Zhenda Zhao, Qizhao Tan, Shang Sun, Chunli Song, Huijie Leng
Risk factors for uroseptic shock in hospitalized patients aged over 80 years with urinary tract infection
Chih-Yen Hsiao, Tsung-Hsien Chen, Yi-Chien Lee, Meng-Chang Hsiao, Peir-Haur Hung, Ming-Cheng Wang
Nine hub genes related to the prognosis of HBV-positive hepatocellular carcinoma identified by protein interaction analysis
Wenhui Xie, Bin Wang, Xiaoting Wang, Diyu Hou, Huiyan Su, Huifang Huang
Plasma vaspin is an effective biomarker for evaluation of future cardiovascular events in patients with chest pain: a 5-year retrospective observational study
Shuya Ji, Wenxin Kou, Peipei Luan, Weixia Jian, Jianhui Zhuang, Xiaopeng Xu, Yifan Zhao, Hailing Li, Wenhui Peng
Dezocine regulates the malignant potential and aerobic glycolysis of liver cancer targeting Akt1/GSK-3β pathway
Zi-Wen Zhong, Wen-Chang Zhou, Xing-Feng Sun, Qi-Chao Wu, Wan-Kun Chen, Chang-Hong Miao
A profiling analysis on the receptor ACE2 expression reveals the potential risk of different type of cancers vulnerable to SARS-CoV-2 infection
Yu-Jun Dai, Fang Hu, Huan Li, Han-Ying Huang, Da-Wei Wang, Yang Liang
Incidence of patients with bone metastases at diagnosis of solid tumors in adults: a large population-based study
Jin-Feng Huang, Jianfei Shen, Xiao Li, Ramesh Rengan, Nicola Silvestris, Minqi Wang, Lisa Derosa, Xuanqi Zheng, Andrea Belli, Xiao-Lei Zhang, Yan Michael Li, Aimin Wu
The JAK2/STAT3 pathway is involved in dexmedetomidine-induced myocardial protection in rats undergoing cardiopulmonary bypass
Sining Pan, Yanhua Chen, Xu Zhang, Yubo Xie
Differential microRNA expression profiles associated with microsatellite status reveal possible epigenetic regulation of microsatellite instability in gastric adenocarcinoma
Xiaofei Qu, Liqin Zhao, Ruoxin Zhang, Qingyi Wei, Mengyun Wang
Validation of the prognostic value of various lymph node staging systems for cervical squamous cell carcinoma following radical surgery: a single‐center analysis of 3,732 patients
Qinhao Guo, Jun Zhu, Yong Wu, Hao Wen, Lingfang Xia, Xingzhu Ju, Guihao Ke, Xiaohua Wu
Automatic classification of esophageal lesions in endoscopic images using a convolutional neural network
Gaoshuang Liu, Jie Hua, Zhan Wu, Tianfang Meng, Mengxue Sun, Peiyun Huang, Xiaopu He, Weihao Sun, Xueliang Li, Yang Chen
Age-adjusted Charlson Comorbidity Index predicts survival in intrahepatic cholangiocarcinoma patients after curative resection
Wei-Feng Qu, Pei-Yun Zhou, Wei-Ren Liu, Meng-Xin Tian, Lei Jin, Xi-Fei Jiang, Han Wang, Chen-Yang Tao, Yuan Fang, Yu-Fu Zhou, Shu-Shu Song, Zhen-Bin Ding, Yuan-Fei Peng, Zhi Dai, Shuang-Jian Qiu, Jian Zhou, Jia Fan, Zheng Tang, Ying-Hong Shi
The therapeutic effect of high-volume hemofiltration on sepsis: a systematic review and meta-analysis
Fan Yin, Fang Zhang, Shijian Liu, Botao Ning
Real-world impact of postmastectomy radiotherapy in T1–2 breast cancer with one to three positive lymph nodes
Feng-Yan Li, Chen-Lu Lian, Jian Lei, Jun Wang, Li Hua, Zhen-Yu He, San-Gang Wu
The expression change of OTUD3-PTEN signaling axis in glioma cells
Yi-Zhen Liu, Xi-Xun Du, Qi-Qi Zhao, Qian Jiao, Hong Jiang
The diagnostic yield of closed needle pleural biopsy in exudative pleural effusion: a retrospective 10-year study
Tianli Zhang, Bing Wan, Li Wang, Chuling Li, Yangyang Xu, Xiangdong Wang, Hongbing Liu, Yong Song, Dang Lin, Ping Zhan, Tangfeng Lv
The role of inflammation in a rat model of chronic thromboembolic pulmonary hypertension induced by carrageenan
Dawen Wu, Yunfei Chen, Wenfeng Wang, Hongli Li, Minxia Yang, Haibo Ding, Xiaoting Lv, Ningfang Lian, Jianming Zhao, Chaosheng Deng
Does the conventional dosage of linezolid necessitate therapeutic drug monitoring?—Experience from a prospective observational study
Jie Fang, Congqin Chen, Yan Wu, Min Zhang, Ying Zhang, Guochao Shi, Yijin Yao, Hong Chen, Xiaolan Bian
Serum levels of olfactomedin 4: a biomarker for asthma control state in asthmatics
Xingyuan Chen, Khan Khalid, Dandan Chen, Chen Qiu
Partially cystic thyroid cancer on conventional and elastographic ultrasound: a retrospective study and a machine learning—assisted system
Hai-Na Zhao, Jing-Yan Liu, Qi-Zhong Lin, Yu-Shuang He, Hong-Hao Luo, Yu-Lan Peng, Bu-Yun Ma
Characteristics of 43 multiple auricular deformity case families and auricle morphology in 463 microtia patients in South China
Hua-Song Zhang, Sui-Jun Chen, Hai-Cang Zeng, Hao Xiong, Jun-Feng Lin, Yao-Dong Xu, Hui-Ying Zhao, Yi-Qing Zheng

Review Article

Coronavirus disease 2019 (COVID-19): the portrait of a perfect storm
Giuseppe Lippi, Fabian Sanchis-Gomar, Brandon M. Henry
The challenges in colorectal cancer management during COVID-19 epidemic
Xianghai Ren, Baoxiang Chen, Yuntian Hong, Weicheng Liu, Qi Jiang, Jingying Yang, Qun Qian, Congqing Jiang
Molecular subtypes and precision treatment of triple-negative breast cancer
Shen Zhao, Wen-Jia Zuo, Zhi-Ming Shao, Yi-Zhou Jiang
A quality evaluation of guidelines on five different viruses causing public health emergencies of international concern
Siya Zhao, Jin Cao, Qianling Shi, Zijun Wang, Janne Estill, Shuya Lu, Xufei Luo, Junxian Zhao, Hairong Zhang, Jianjian Wang, Qi Wang, Yangqin Xun, Jingyi Zhang, Meng Lv, Yunlan Liu, Xiaomin Nie, Ling Wang, Xianzhuo Zhang, Weiguo Li, Enmei Liu, Xiaohui Wang, Yaolong Chen, on behalf of COVID-19 evidence and recommendations working group
Bridging the “last mile” gap between AI implementation and operation: “data awareness” that matters
Federico Cabitza, Andrea Campagner, Clara Balsano
Primary small cell carcinoma of the esophagus: progression in the last decade
Anqi Ji, Runsen Jin, Renquan Zhang, Hecheng Li

Study Protocol

Extubation strategies in neuro-intensive care unit patients and associations with outcomes: the ENIO multicentre international observational study
Raphaël Cinotti, Paolo Pelosi, Marcus J. Schultz, Ioakeimidou Aikaterini, Pablo Alvarez, Rafael Badenes, Victoria Mc Credie, Abdurrahmaan Suei Elbuzidi, Muhammed Elhadi, Daniel Agustin Godoy, Mohan Gurjar, Matthias Haenggi, Callum Kaye, Julio Cesar Mijangos-Méndez, Michael Piagnerelli, Romain Piracchio, Syed Tariq Reza, Robert D. Stevens, Ueno Yoshitoyo, Karim Asehnoune, on behalf of the ENIO Study Group

Editorial Commentary

Impact of renal impairment on light chain amyloidosis outcomes after autologous hematopoietic stem cell transplantation
Samer A. Srour, Muzaffar H. Qazilbash
Unicompartmental knee arthroplasty over total knee arthroplasty: a more cost-effective strategy for treating medial compartment arthritis
Samuel W. Carlson, Rafael J. Sierra
FLT3-IRAK dual targeting: an exciting new therapeutic option guided by adaptive activation of immune response pathways
Cara A. Rabik, Jiawan Wang, Christine A. Pratilas
Cost of cardiovascular disease prevention: towards economic evaluations in prevention programs
João Vasco Santos, Désirée Vandenberghe, Mariana Lobo, Alberto Freitas
Correlation between corticosteroid injections and surgical site infections in shoulder arthroscopy
Riccardo Compagnoni, Pietro Randelli
The role of gender disparities in kidney injury
Raymond C. Harris, Ming-Zhi Zhang
Symptomatic adult spinal deformity: implications for treatment and research
Fabio Zaina, Francesca Di Felice, Sabrina Donzelli, Stefano Negrini
No free lunch—the price of double versus triple antithrombotic therapy in patients with atrial fibrillation after ACS or PCI
Marco Valgimigli, Felice Gragnano
Keynote 42: Pembrolizumab, PD-L1, and where to draw the line
James Isaacs, Jeffrey Clarke, Neal Ready