Home - Annals of Translational Medicine

Focus on “Mesothelioma” guest edited by Drs. Andrea S. Wolf and Raja M. Flores

This special issue of the Annals of Translational Medicine details an in-depth description of the most relevant topics on malignant pleural mesothelioma (MPM). The discussions include fascinating discoveries that deepened our understanding of the environmental and genetic exposures that cause this aggressive disease, reviews of traditional and novel approaches to staging it, and the complex multimodality therapies that have improved outcomes from no long-term survival to 15–24% 5-year-survival with treatment. Up-to-date reviews of radiation therapy are presented, including the latest results and commentary on induction radiation and hemithoracic radiation after pleurectomy/decortication (P/D)...

Focus on “Capsule Endoscopy” guest edited by Drs. Anastasios Koulaouzidis and Mark E. McAlindon

In this issue devoted to small bowel capsule endoscopy, we reflect on how far we have come since the first models were introduced and what future practice might look like. Contributions also include reviews of small bowel bleeding and coeliac disease, two of the commonest indications for capsule endoscopy, articles on capsule retention and a perspective of one nation's experience in the field.

Impact of sleep apnea on in-hospital outcomes after transcatheter aortic valve replacement: insight from National Inpatient Sample database 2011–2014

Sleep apnea is associated with worse outcomes following various kinds of surgeries. There is a paucity of data on the association of sleep apnea with clinical outcomes after transcatheter aortic valve replacement (TAVR).

MDA5 autoantibody—another indicator of clinical diversity in dermatomyositis

Allenbach and colleagues have recently reported for the first time the results of an intriguing study of the histopathologic, immunopathologic and gene expression differences in muscle biopsy tissue from adult dermatomyositis (DM) patients who do and do not have circulating MDA5 autoantibodies (anti-MDA5). Anti-MDA5 were originally identified in a clinically-defined subset of DM patients whose disease was expressed predominately in the skin for unusually long periods of time without accompanying muscle weakness [i.e., “clinically-amyopathic DM” (CADM)] and were at risk for acute, rapidly-progressive form of interstitial lung disease (ILD)...

Message from the APCHG 2017 Organizing Committee

Dear friends/delegates,

Greetings from the Organizing Committee of the 12th Asia-Pacific Conference on Human Genetics (APCHG 2017).

On behalf of the local organizing committee, we are pleased to invite you to participate in the 12th Asia-Pacific Conference on Human Genetics (APCHG 2017) to be held from November 8 (Wednesday) -10 (Friday), 2017 at the Royal Orchid Sheraton Hotel & Towers in Bangkok, Thailand.

Welcome to the Ninth Postgraduate Course on “Surgery of The Thoracic Aorta”!

The Ninth Postgraduate Course on “Surgery of The Thoracic Aorta” is going to take place in Bologna from 13th to 14th November 2017.

This interactive meeting will focus on open, hybrid, transcatheter and endovascular techniques employed during operations on the thoracic aorta.

2016 Annual Report of ATM

Greetings from Profs. Jianxing He, Rafael Rosell, Xuehao Wang, and Editorial Office of ATM！

We are glad to present the 2016 Annual Report of ATM here. In 2016, ATM progressed fast and smoothly under the join-efforts of experts worldwide. The total citation number has significantly increased from 309 in January to 1294 in December. The journal was exhibited in some international meetings, to attract wider attention and exposure. More information is shown in the Annual Report.

We would like to express sincere appreciation for the enthusiastic and vigorous support and contributions from all board members, guest editors, reviewers, authors, readers, etc. We wish you a happy, healthy and prosperous 2017! Read More>>

Testimonials for ATM from Eminent Experts Worldwide

In less than two months, ATM has received about 30 supporting letters from the prominent experts worldwide, who are editorial board members, authors and readers knowing ATM well. This is encouraging. We are grateful for their vigorous support to the journal.

Below abstracts some parts from their supporting letters.

Asian Society of Thoracic Surgery (ASTS) was officially launched: collaborate across Asia and the world

On July 31, the 2^nd Consultative Meeting on Asian Cooperation in Thoracic Surgery was successfully held in Beijing. The panel for the meeting include Prof. Jie He (Chairman & Host), the President of Cancer Hospital Chinese Academy of Medical Sciences and Director of National Cancer Center of China, Academician of Chinese Academcy of Sciences; Prof. Alan Sihoe (Moderator) from University of Hong Kong; Prof. Jose Luis Danguilan, Prof. Shugeng Gao, Porf. Diego Gonzalez-Rivas, Prof. Jheon Sanghoon, Prof. Ali Zamir Khan, Prof. Lee Jang-Ming, Prof. Toriaki Morikawa, Prof. Meinoshin Okumura, Prof. Punnarerk Thongcharoen and Mr. Stephen Wang.

‹ ›

Vol 5, No 12 (June, 2017)

About atm

Manuscript Submission

Advertising

Contact us

General editorial enquiries:
Email: editor@atmjournal.org
Copyright related contact:
Email: permissions@amegroups.com
Commercial Sales contact (Reprints, advertising, etc.):
Email: sales@amegroups.com

Focused Issues more

Focus on “Capsule Endoscopy” More >>

Focus on “Mesothelioma” More >>

Focus on “The Human Microbiome in Urologic Health and Disease” More >>

Endorsement

Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.

the Brazilian Society of Thoracic Surgery(SBCT)

the Bonnie J. Addario Lung Cancer Foundation (ALCF)

Preface on From Microbe to Microbiome: New Implication in Respiratory & Critical Care Medicine

Human microbiome in respiratory diseases

Maria Ruiz-Rodriguez, Jordi Rello

PDF HTML

Review Article on From Microbe to Microbiome: New Implication in Respiratory & Critical Care Medicine

Insights into study design and statistical analyses in translational microbiome studies

Jyoti Shankar

PDF HTML

The respiratory microbiome in idiopathic pulmonary fibrosis

Richard J. Hewitt, Philip L. Molyneaux

PDF HTML

Microbiome in chronic obstructive pulmonary disease

Eduard Monsó

PDF HTML

Original Article

Obesity among Sudanese adults with diabetes: a population-based survey

Yasmeen A. Ali, Ahmed O. Almobarak, Heitham Awadalla, Wadie M. Elmadhoun, Mohamed H. Ahmed

PDF HTML

Computer tomography guided lung biopsy using interactive breath-hold control: a randomized study

Haseem Ashraf, Shella Krag-Andersen, Matiullah Naqibullah, Valentina Minddal, Annette Nørgaard, Therese Maria Henriette Naur, Peter Sand Myschetzky, Paul Frost Clementsen

PDF HTML

Barriers and enablers to proper diabetic foot care amongst community dwellers in an Asian population: a qualitative study

Andrew Arjun Sayampanathan, Amit Nirmal Cuttilan, Christopher J. Pearce

PDF HTML

Influence of ABO blood group on sports performance

Giuseppe Lippi, Giorgio Gandini, Gian Luca Salvagno, Spyros Skafidas, Luca Festa, Elisa Danese, Martina Montagnana, Fabian Sanchis-Gomar, Cantor Tarperi, Federico Schena

PDF HTML

Review Article

Abdominal aortic aneurysm: pictorial review of common appearances and complications

Yogesh Kumar, Kusum Hooda, Shuo Li, Pradeep Goyal, Nishant Gupta, Melkamu Adeb

PDF HTML

Column in Laboratory Medicine

Overcoming preanalytical issues for diagnosing diabetes with fasting plasma glucose

Martina Montagnana, Giuseppe Lippi

PDF HTML

Editorial

Exosomes derived from stimulated monocytes promote endothelial dysfunction and inflammation in vitro

Javier Roig-Arcos, Daniel López-Malo, Manuel Díaz-Llopis, Francisco J. Romero

PDF HTML

Hypertension and cognitive impairment

Wilbert S. Aronow

PDF HTML

Personalised information for improving the uptake of smoking cessation programs

Monika Semwal, Gemma Taylor, Josip Car

PDF HTML

Diabetes mellitus and multivessel coronary artery disease: an ongoing battle for an ideal treatment strategy

Laura S. Kerkmeijer, Serdar Farhan, Roxana Mehran, George D. Dangas

PDF HTML

Sternal wound management after bilateral internal thoracic artery grafting: a significant detail

Giuseppe Gatti

PDF HTML

Extracellular vesicle isolation: present and future

Istvan Furi,, Fatemeh Momen-Heravi, Gyongyi Szabo

PDF HTML

Atherosclerotic renal artery stenosis

Wilbert S. Aronow

PDF HTML

Atezolizumab in non-small cell lung cancer: the era of precision immuno-oncology

James Chung Hang Chow, Ka Man Cheung, William Chi Shing Cho

PDF HTML

Hypertensive disorders in pregnancy

Wilbert S. Aronow

PDF HTML

Meet the Professor

Interview with Prof. Bo Shen: the current status of pouch

Jessie Zhong, Maxine Feng

PDF HTML

Review Articles

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology

Antonio Franchitto, Paolo Onori, Anastasia Renzi, Guido Carpino, Romina Mancinelli, Domenico Alvaro, Eugenio Gaudio

The significance of genetics for cholangiocarcinoma development

Luca Maroni, Irene Pierantonelli, Jesus M. Banales, Antonio Benedetti, Marco Marzioni

Functional role of microvesicles in gastrointestinal malignancies

Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng

The fetal liver as cell source for the regenerative medicine of liver and pancreas

Rossella Semeraro, Vincenzo Cardinale, Guido Carpino, Raffaele Gentile, Cristina Napoli, Rosanna Venere, Manuela Gatto, Roberto Brunelli, Eugenio Gaudio, Domenico Alvaro

Editorial

Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?

Jayoung Kim, Wun-Jae Kim

Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era

Kimberly J. Payne, Abigail Benitez, Sinisa Dovat

Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?

Kevin P. Daly

Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized

Mark R. Walter

Safe anticoagulation when heart and lungs are “on vacation”

Marina A. Dobrovolskaia, Scott E. McNeil

γδ T cells and immunity to human malaria in endemic regions

Samarchith P. Kurup, John T. Harty

Apyrase as a novel therapeutic inhibitor of heterotopic ossification

Olin D. Liang, Anthony M. Reginato, Damian Medici

The CRISPR road: from bench to bedside on an RNA-guided path

Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort

Microbiome, a new dimension in cancer research

Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei

Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome

Irfana Muqbil, Ramzi M. Mohammad

Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?

Sarina Bains, Prasad S. Adusumilli

Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy

Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli

Radiotherapy: killing with complement

Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming

Getting to the core of fibrosis: targeting redox imbalance in aging

Louise Hecker, Victor J. Thannickal

Perspective

Integrating bevacizumab and radiation treatment of brain metastasis: is there sense and sensibility in this approach?

Emil Lou, Paul W. Sperduto

Commentary

Applications of iPSC-derived models of Gaucher disease

Daniel K. Borger, Elma Aflaki, Ellen Sidransky

The impact of sedation protocols on outcomes in critical illness

Benjamin Scott, Tobias Eckle

Review Article

Osteonecrosis of the knee: review

Ammar R. Karim, Jeffrey J. Cherian, Julio J. Jauregui, Todd Pierce, Michael A. Mont

Update in genetic susceptibility in melanoma

Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig

State of the art management of metastatic gastroesophageal cancer

Adrian G. Murphy, David Lynch, Ronan J. Kelly

Original Article

Hyaluronan expression in primary and secondary brain tumors

Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari

Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy

Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers

Letter to the Editor

Gene replacement rescues severe muscle pathology and prolongs survival in myotubularin-deficient mice and dogs

Martin K. Childers, Alan H. Beggs, Ana Buj-Bello

Review Articles

Functional role of microvesicles in gastrointestinal malignancies

Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng

Effect of high fat-diet and obesity on gastrointestinal motility

Mazen Al Mushref, Shanthi Srinivasan

The physiological roles of secretin and its receptor

Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds

Noorjahan Panjwani

Editorial: Diabetes Mellitus

A look at the trend in diabetes-related complications in the U.S. over the past two decades: looking ahead

Chee W. Chia, Luigi Ferrucci

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test

Takahiro Uotani, David Y. Graham

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease

Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease

David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease

Christiane Reitz

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.

Preface

Cancer diagnostics: current concepts and future perspectives

Martina Montagnana, Giuseppe Lippi

Editorial

Secondary analysis of electronic health records in critical care medicine

Sven Van Poucke, Alberto Alexander Gayle, Milan Vukicevic

Favorable outcomes for female patients undergoing transcatheter aortic valve replacement?

Masahiko Asami

The gender paradox in TAVR

Anat Berkovitch, Israel M. Barbash

Lessons from the arterial revascularization trial

Hugh S. Paterson, Paul G. Bannon

A sweet decision: treatment of stable coronary artery disease in patients with diabetes mellitus

Christoph Sinning, Dirk Westermann

Is it time to get some SHUT-i?

Jason G. Ellis, Julie Seed, Celyne H. Bastien, Michael A. Grandner

CBT-I and the short sleep duration insomnia phenotype: a comment on Bathgate, Edinger and Krystal

Celyne H. Bastien, Jason G. Ellis, Michael Grandner

Classification criteria in Sjögren’s syndrome

Chiara Baldini, Francesco Ferro, Stefano Bombardieri

Evolving treatment options for valve and aortic disease with bicuspid aortic valve

Nicholas S. Burris, Michael D. Hope

Another passenger for the TAVR speeding train

Chiara Fraccaro,, Daisuke Ueshima,, Giuseppe Tarantini

To repair or to replace: four decades in the making

Patpilai Kasinpila, Y. Joseph Woo

Ethical challenges and terminal deactivation of left ventricular assist device

Tony Makdisi, George Makdisi

Sex differences in outcomes with transcatheter aortic valve replacement

Feng Qian, Edward L. Hannan

Searching for the perfect lymphadenectomy

Federico Venuta, Daniele Diso, Erino A. Rendina, Marco Anile

Positron emission tomography imaging in diffuse intrinsic pontine glioma

Norbert Galldiks, Carina Stegmayr, Antje Willuweit, Karl-Josef Langen

Radial artery and right internal thoracic artery: jousting for the throne of coronary artery bypass grafting

Massimo Baudo, Mario Gaudino

Exosomes may play a crucial role in HIV dendritic cell immunotherapy

Benjamin Wolfson, Justine E. Yu, Qun Zhou

Transcatheter mitral valve replacement: still a long way to go!

Thierry Carrel

Shared decision making in the treatment of stage I non small cell lung cancer—a choice which should equally involve both sides

Aurel Ottlakan, Jozsef Furak, Gaetano Rocco

Drug-induced causes of secondary hypertension

Wilbert S. Aronow

Lung cancer prognosis: can histological patterns and morphological features have a role in the management of lung cancer patients?

Silvia Rinaldi, Rossana Berardi

Population health’s unanimity on lung cancer screening: far ahead of medical advice

Bruce Pyenson, Claudia I. Henschke, David F. Yankelevitz

Perspective

The subtypes of microscopic colitis from a pathologist’s perspective: past, present and future

Peter Johan Heiberg Engel, Anne-Marie Kanstrup Fiehn, Lars Kristian Munck, Martin Kristensson

Appropriateness of tumor marker request: a case of study

Massimo Gion, Chiara Trevisiol, Aline S. C. Fabricio

BRCA population screening for predicting breast cancer: for or against?

Giuseppe Lippi, Camilla Mattiuzzi, Martina Montagnana

Commentary

Integrative research agenda for diagnosis in sepsis

Katie Nolan, Ruth O’Leary, Lieuwe Bos, Ignacio Martin-Loeches

Review Article

Microscopic colitis—microbiome, barrier function and associated diseases

Saskia van Hemert, Karolina Skonieczna-Żydecka, Igor Loniewski, Piotr Szredzki, Wojciech Marlicz

Thoracic perforations—surgical techniques

Atilla Eroglu, Yener Aydin, Omer Yilmaz

What are the ethical aspects surrounding the collegial decisional process in limiting and withdrawing treatment in intensive care?

Jean-Pierre Quenot, Fiona Ecarnot, Nicolas Meunier-Beillard, Auguste Dargent, Audrey Large, Pascal Andreu, Jean-Philippe Rigaud

A few realistic questions raised by organ retrieval in the intensive care unit

Olivier Lesieur, Liliane Genteuil, Maxime Leloup

Circulating biomarkers in epithelial ovarian cancer diagnosis: from present to future perspective

Martina Montagnana, Marco Benati, Elisa Danese

Ablation of long-standing persistent atrial fibrillation

Behram P. Mody, Anoshia Raza, Jason Jacobson, Sei Iwai, Daniel Frenkel, Rhadames Rojas, Wilbert S. Aronow

Type 2 diabetes mellitus and risk of hepatocellular carcinoma: spotlight on nonalcoholic fatty liver disease

Alessandro Mantovani, Giovanni Targher

Ethical challenges involved in obtaining consent for research from patients hospitalized in the intensive care unit

Fiona Ecarnot, Jean-Pierre Quenot, Guillaume Besch, Gaël Piton

What are the ethical issues in relation to the role of the family in intensive care?

Jean-Pierre Quenot, Fiona Ecarnot, Nicolas Meunier-Beillard, Auguste Dargent, Audrey Large, Pascal Andreu, Jean-Philippe Rigaud

Epigenetics of colorectal cancer: emerging circulating diagnostic and prognostic biomarkers

Elisa Danese, Martina Montagnana

A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi

Georgios Karaolanis, Demetrios Moris, Chris Bakoyiannis, Diamantis I. Tsilimigras, Viktoria-Varvara Palla, Eleftherios Spartalis, Dimitrios Schizas, Sotirios Georgopoulos

Liquid biopsies in lung cancer—time to implement research technologies in routine care?

Linda Köhn, Mikael Johansson, Kjell Grankvist, Jonas Nilsson

Circulating microRNAs as emerging non-invasive biomarkers for gliomas

Alessandra Santangelo, Anna Tamanini, Giulio Cabrini, Maria Cristina Dechecchi

The role of reactive oxygen species in myocardial redox signaling and regulation

Demetrios Moris, Michael Spartalis, Eleni Tzatzaki, Eleftherios Spartalis, Georgia-Sofia Karachaliou, Andreas S. Triantafyllis, Georgios I. Karaolanis, Diamantis I. Tsilimigras, Stamatios Theocharis

Establishing an evaluation mode with multiple primary outcomes based on combination of diseases and symptoms in TCM clinical trials

Jing Hu, Shuo Liu, Weihong Liu, Huina Zhang, Jing Chen, Hongcai Shang

Molecular mechanisms of programmed cell death-1 dependent T cell suppression: relevance for immunotherapy

Miren Zuazo, Maria Gato-Cañas, Noelia Llorente, María Ibañez-Vea, Hugo Arasanz, Grazyna Kochan, David Escors

Predictors of treatment failure and clinical stability in patients with community acquired pneumonia

Deirdre Morley, Antoni Torres, Catia Cillóniz, Ignacio Martin-Loeches

Prognostic value of red blood cell distribution width in hepatocellular carcinoma

Goyal Hemant, Zhi-De Hu

Overcoming resistance to BRAF inhibitors

Imanol Arozarena, Claudia Wellbrock

Neopterin as a biomarker of immune response in cancer patients

Bohuslav Melichar, Martina Spisarová, Marie Bartoušková, Lenka Kujovská Krčmová, Lenka Javorská, Hana Študentová

Prone positioning acute respiratory distress syndrome patients

Claude Guérin

Spontaneous breathing: a double-edged sword to handle with care

Tommaso Mauri, Barbara Cambiaghi, Elena Spinelli, Thomas Langer, Giacomo Grasselli

Original Article

Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes

Elisa Danese, Giuseppe Lippi, Ruggero Buonocore, Marco Benati, Chiara Bovo, Chiara Bonaguri, Gian Luca Salvagno, Giorgio Brocco, Dirk Roggenbuck, Martina Montagnana