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Focus on “New Image Diagnostic and Therapeutic Modalities in Thoracic Surgery” More >>
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Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.


the Brazilian Society of Thoracic Surgery(SBCT)

the Brazilian Society of Thoracic Surgery(SBCT) the Bonnie J. Addario Lung Cancer Foundation (ALCF)

Original Article

High performance of intravoxel incoherent motion diffusion MRI in detecting viral hepatitis-b induced liver fibrosis
Hua Huang, Nazmi Che-Nordin, Li-Fei Wang, Ben-Heng Xiao, Olivier Chevallier, Yong-Xing Yun, Sheng-Wen Guo, Yì Xiáng J. Wáng
Non-intubated thoracoscopic surgery for lung cancer in patients with impaired pulmonary function
Man-Ling Wang, Ming-Hui Hung, Hsao-Hsun Hsu, Kuang-Cheng Chan, Ya-Jung Cheng, Jin-Shing Chen
Medium-term outcome of cementless, mobile-bearing, unicompartmental knee arthroplasty
Radosław Stempin, Kacper Stempin, Wiesław Kaczmarek
Receptor-interacting protein kinase 3 as a predictive adjuvant chemotherapy marker after lung adenocarcinoma resection
Jae Heun Chung, Seong Hoon Yoon, Yong Jung Kang, Yun Seong Kim, Bong Soo Son, Ryuk Jun Kwon, Jun Hee Han, Do Hyung Kim
Pulmonary nodular lymphoid hyperplasia: a rare benign disease with malignant mask
Likui Fang, Jinming Xu, Luming Wang, Zhehao He, Wang Lv, Jian Hu
Predictive risk factors of acute kidney injury after on-pump coronary artery bypass grafting
Jin-Tae Kwon, Tae-Eun Jung, Dong-Hyup Lee
Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis
Fuqiang Li, Yijun Wu, Liang Chen, Liang Hu, Xiaosun Liu
Predictors of blood transfusion and in-hospital outcomes in patients with gastric antral vascular ectasia (GAVE): a nationwide population-based analysis
Upenkumar Patel, Rupak Desai, Jiten Desai, Nanush Damarlapally, Dipen Zalavadia, Mohamad Yousef, Roxana Coman, Pardeep Bansal, Hemant Goyal
An evaluation of adult critical result policies in haematology in a teaching hospital in China
Dagan Yang, Qian Cai, Xinglun Qi, Lili Xu, Yunxian Zhou
Short-term outcomes after anatomic total shoulder arthroplasty in patients with osteoarthritis versus osteonecrosis
Sergio M. Navarro, Heather S. Haeberle, Anton Khlopas, Jared M. Newman, Jaret M. Karnuta, Michael A. Mont, Prem N. Ramkumar

Case Report

Left lower lobe sleeve resection for endobronchial schwannoma
Hu Liao, Wenpeng Song, Nan Chen, Fengning Chen, Chengwu Liu, Feng Lin
Rare paraneoplastic erythroderma associated with ectopic neuron-specific enolase deposition in basal cells
Lei Wang, Ting Guo, Hao Zhang, Weimiao Li, Yifang Zhu, Haihua Guo, Feng Yang, Yitong Guo, Zhipei Zhang, Yong Han, Daixing Zhong, Xiaofei Li, Lijun Huang
A rare presentation of pleomorphic carcinoma of lung mimic empyema
Kuo-Ming Yang, En-Kuei Tang, Yih-Gang Goan, Yen-Chiang Tseng
Cardiac penetrating injury: a rare complication associated with the lung nodule localization by hookwire
Zhe Shi, Yuxing Jin, Chang Chen
Aprepitant for gefitinib-induced refractory pruritus in Chinese malignancy population
Haifeng Qin, Fang Wang, Ke Wang, Hui Liu, Rui Guo, Zhen Zeng, Xin Pan, Xiaofeng Fu, Ting Zhang, Hongjun Ga


Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?
Jayoung Kim, Wun-Jae Kim
Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era
Kimberly J. Payne, Abigail Benitez, Sinisa Dovat
Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?
Kevin P. Daly
Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized
Mark R. Walter
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
γδ T cells and immunity to human malaria in endemic regions
Samarchith P. Kurup, John T. Harty
Apyrase as a novel therapeutic inhibitor of heterotopic ossification
Olin D. Liang, Anthony M. Reginato, Damian Medici
The CRISPR road: from bench to bedside on an RNA-guided path
Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort
Microbiome, a new dimension in cancer research
Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei
Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome
Irfana Muqbil, Ramzi M. Mohammad
Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?
Sarina Bains, Prasad S. Adusumilli
Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy
Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli
Radiotherapy: killing with complement
Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming
Getting to the core of fibrosis: targeting redox imbalance in aging
Louise Hecker, Victor J. Thannickal
The Art of War and oncology: applying the principles of strategy and tactics to greater effect in the era of targeted therapy
Emil Lou
Protecting functional β cells with a therapeutic peptide
Meghan L. Marré, Jon D. Piganelli, Eddie A. James
Acidosis and citrate: provocative interactions
Kathleen S. Hering-Smith, L. Lee Hamm


Applications of iPSC-derived models of Gaucher disease
Daniel K. Borger, Elma Aflaki, Ellen Sidransky
The impact of sedation protocols on outcomes in critical illness
Benjamin Scott, Tobias Eckle

Review Article

Osteonecrosis of the knee: review
Ammar R. Karim, Jeffrey J. Cherian, Julio J. Jauregui, Todd Pierce, Michael A. Mont
Update in genetic susceptibility in melanoma
Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly
Colorectal cancer genomics and designing rational trials
Sebastian Mondaca, Rona Yaeger
Emerging application of genomics-guided therapeutics in personalized lung cancer treatment
Aubhishek Zaman, Trever G. Bivona
Aminoquinoline antimalarial therapy in dermatomyositis—are we missing opportunities with respect to comorbidities and modulation of extracutaneous disease activity?
Richard D. Sontheimer

Original Article

Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari
Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers

Review Articles

Functional role of microvesicles in gastrointestinal malignancies
Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng
Effect of high fat-diet and obesity on gastrointestinal motility
Mazen Al Mushref, Shanthi Srinivasan
The physiological roles of secretin and its receptor
Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds
Noorjahan Panjwani

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test
Takahiro Uotani, David Y. Graham

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease
Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease
David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease
Christiane Reitz

Editorial on Cardiovascular Disease and Cardiometabolic Risk: Advances in Understanding Pathophysiology, Public Health Burden and Clinical Care

Advances in resistant hypertension
David A. Calhoun

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.




Review Article

Original Article

Case Report

Letter to the Editor

Surgical Technique

Expert Consensus