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Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.


the Brazilian Society of Thoracic Surgery(SBCT)

the Brazilian Society of Thoracic Surgery(SBCT) the Bonnie J. Addario Lung Cancer Foundation (ALCF)

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Annals of Translational Medicine is sponsored by the Affiliated Nanjing Jiangning Hospital of Nanjing Medical University.

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Original Article

In vitro prediction of breast cancer therapy toxicity
Michael J. McKay, Jezzie Maneerat, Timothy M. McKay, Jeremy N. McKay, Reza Masoud-Rahbari
Bioaerosols in the lungs of subjects with different ages—Part 2: clearance modeling
Robert Sturm
Non-homologous end-joining protein expression screen from radiosensitive cancer patients yields a novel DNA double strand break repair phenotype
Michael J. McKay, Su Kak Goh, Jeremy N. McKay, Michael Chao, Timothy M. McKay
Is the SenseWear Armband accurate enough to quantify and estimate energy expenditure in healthy adults?
Alejandro Santos-Lozano, Adrián Hernández-Vicente, Raúl Pérez-Isaac, Fernanda Santín-Medeiros, Carlos Cristi-Montero, Jose Antonio Casajús, Nuria Garatachea
Survival of primary lung cancer patients in Brunei Darussalam, 1987–2012
Lin Naing, Amalina Abdullah, Syafiq Abdullah, Nurolaini Kifli
The effect of financial crisis on the profile of the patients examined at the surgical emergencies of an academic institution in Greece
Michael Kontos, Demetrios Moris, Spyridon Davakis, Dimitrios Schizas, Emmanouil Pikoulis, Theodoros Liakakos

Systematic Review and Meta-Analysis

Surgical prophylaxis with gentamicin and acute kidney injury: a systematic review and meta-analysis
Weeraporn Srisung, Jirapat Teerakanok, Pakpoom Tantrachoti, Amputch Karukote, Kenneth Nugent

Surgical Technique

Use of distal perfusion in peripheral extracorporeal membrane oxygenation
George Makdisi, Tony Makdisi, I-Wen Wang


High-flow nasal cannula is superior to noninvasive ventilation to prevent reintubation?
Masaji Nishimura
Is there a benefit to locally consolidative therapy for oligometastatic non-small cell lung cancer?
Lauren Boreta, Sue S. Yom
Neonatal Ebstein repair—where are we now?
Philip L. Wackel, Joseph A. Dearani, Frank Cetta
Liposteroid therapy for juvenile and adult dermatomyositis: efficacy and side effects
Hiroyuki Wakiguchi
Not all extracellular vesicles were created equal: clinical implications
Alberto Ortiz
Extra corporeal membrane oxygenation support: ethical dilemmas
Tony Makdisi, George Makdisi
Targeting the seeds of small cell lung cancer
Sylvia Mahara, Ron Firestein
Ultrasound to assess diaphragmatic function in the critically ill—a critical perspective
Mark Haaksma, Pieter Roel Tuinman, Leo Heunks
Future directions of extracellular vesicle-associated miRNAs in metastasis
Jesús Adrián López, Angelica Judith Granados-López
On vs. off pump coronary artery bypass grafting: the next chapter
Nicola King
Is the exosome a potential target for cancer immunotherapy?
Akihiko Yoshimura, Kenjiro Sawada, Tadashi Kimura
Next steps to improve disparities in lung cancer treatment clinical trial enrollment
Leah L. Zullig, William R. Carpenter, Christina D. Williams
Meta-analysis on extracorporeal life support during cardiac arrest: do not compare apples and oranges
Sacha Rozencwajg, Matthieu Schmidt


Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?
Jayoung Kim, Wun-Jae Kim
Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era
Kimberly J. Payne, Abigail Benitez, Sinisa Dovat
Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?
Kevin P. Daly
Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized
Mark R. Walter
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
γδ T cells and immunity to human malaria in endemic regions
Samarchith P. Kurup, John T. Harty
Apyrase as a novel therapeutic inhibitor of heterotopic ossification
Olin D. Liang, Anthony M. Reginato, Damian Medici
The CRISPR road: from bench to bedside on an RNA-guided path
Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort
Microbiome, a new dimension in cancer research
Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei
Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome
Irfana Muqbil, Ramzi M. Mohammad
Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?
Sarina Bains, Prasad S. Adusumilli
Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy
Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli
Radiotherapy: killing with complement
Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming
Getting to the core of fibrosis: targeting redox imbalance in aging
Louise Hecker, Victor J. Thannickal


Applications of iPSC-derived models of Gaucher disease
Daniel K. Borger, Elma Aflaki, Ellen Sidransky
The impact of sedation protocols on outcomes in critical illness
Benjamin Scott, Tobias Eckle

Review Article

Osteonecrosis of the knee: review
Ammar R. Karim, Jeffrey J. Cherian, Julio J. Jauregui, Todd Pierce, Michael A. Mont
Update in genetic susceptibility in melanoma
Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly

Original Article

Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari
Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers

Review Articles

Functional role of microvesicles in gastrointestinal malignancies
Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng
Effect of high fat-diet and obesity on gastrointestinal motility
Mazen Al Mushref, Shanthi Srinivasan
The physiological roles of secretin and its receptor
Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds
Noorjahan Panjwani

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test
Takahiro Uotani, David Y. Graham

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease
Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease
David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease
Christiane Reitz

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.


Paul A. J. Beckers, Paul E. Van Schil




Review Article

Original Article

Case Report


Review Article on Treatment for Hepatitis B