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Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.


the Brazilian Society of Thoracic Surgery(SBCT)

the Brazilian Society of Thoracic Surgery(SBCT) the Bonnie J. Addario Lung Cancer Foundation (ALCF)

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Annals of Translational Medicine is sponsored by the Affiliated Nanjing Jiangning Hospital of Nanjing Medical University.

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Preface on Quality in Gastrointestinal Endoscopy

Quality in gastrointestinal endoscopy: the preface
Konstantinos Triantafyllou, Spyridon Michopoulos, Cesare Hassan

Review Article on Quality in Gastrointestinal Endoscopy

Critical appraisal of guidelines for screening and surveillance of Barrett’s esophagus
Spyridon Michopoulos
What defines quality in small bowel capsule endoscopy
Ioannis V. Mitselos, Dimitrios K. Christodoulou
Quality in upper gastrointestinal endoscopic submucosal dissection
Flaminia Purchiaroni, Guido Costamagna, Cesare Hassan
Ten quality indicators for endoscopic submucosal dissection: what should be monitored and reported to improve quality
Lorenzo Fuccio, Pradeep Bhandari, Roberta Maselli, Leonardo Frazzoni, Thierry Ponchon, Franco Bazzoli, Alessandro Repici

Original Article on Quality in Gastrointestinal Endoscopy

Monitoring of colonoscopy quality indicators in an academic endoscopy facility reveals adherence to international recommendations
Stefanos Karamaroudis, Aliki Stamou, Stamatia C. Vorri, Paraskevas Gkolfakis, Vasilios Papadopoulos, Georgios Tziatzios, Aikaterini Karagouni, Panagiota Katsouli, George D. Dimitriadis, Konstantinos Triantafyllou

Review Article on Quality in Gastrointestinal Endoscopy

Quality in endoscopy training—the endoscopic retrograde cholangiopancreatography case
Ivan Jovanovic, Klaus Mönkemüller
How to measure quality in endoscopic retrograde cholangiopancreatography (ERCP)
Alexander Krumov Katzarov, Zdravko Ivanov Dunkov, Ivan Popadiin, Krum Sotirov Katzarov
How to measure quality in endoscopic ultrasound
Antonio Facciorusso, Rosario Vincenzo Buccino, Nicola Muscatiello

Case Report on Quality in Gastrointestinal Endoscopy

Full spectrum endoscopy for an easy and adequate visualization of Vater’s papilla
Ioannis S. Papanikolaou, Georgios Tziatzios, Paraskevas Gkolfakis, Konstantinos Triantafyllou
Adhering to quality medical care: a case report of upper gastrointestinal bleeding due to self-expandable metal stent placed for benign duodenal obstruction
Polychronis Gatos-Gatopoulos, Georgios Tziatzios, Paraskevas Gkolfakis, Konstantinos Triantafyllou

Original Article

Use of lung-protective strategies during one-lung ventilation surgery: a multi-institutional survey
Biniam Kidane, Stephen Choi, Dalilah Fortin, Turlough O’Hare, George Nicolaou, Neal H. Badner, Richard I. Inculet, Peter Slinger, Richard A. Malthaner
Health-related quality of life measure distinguishes between low and high clinical T stages in esophageal cancer
Biniam Kidane, Amir Ali, Joanne Sulman, Rebecca Wong, Jennifer J. Knox, Gail E. Darling
DUSP2 methylation is a candidate biomarker of outcome in head and neck cancer
Cristiana Lo Nigro, Daniela Vivenza, Nerina Denaro, Laura Lattanzio, Mirella Fortunato, Tim Crook, Marco Carlo Merlano

Case Report

Management of ruptured liver segment IV hepatocellular carcinoma: is transarterial embolization (TAE) superior to chemoembolization (TACE)? —the jury is still out
Anargyros Bakopoulos, Nikolaos Koliakos, Diamantis I. Tsilimigras, Dimitrios Schizas, Demetrios Moris, Argiris Angelopoulos, Spyridon Spanakos, Eleftherios Spartalis, Pavlos Patapis, Panagiotis Skandalakis, Theodoros Troupis


Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?
Jayoung Kim, Wun-Jae Kim
Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era
Kimberly J. Payne, Abigail Benitez, Sinisa Dovat
Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?
Kevin P. Daly
Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized
Mark R. Walter
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
γδ T cells and immunity to human malaria in endemic regions
Samarchith P. Kurup, John T. Harty
Apyrase as a novel therapeutic inhibitor of heterotopic ossification
Olin D. Liang, Anthony M. Reginato, Damian Medici
The CRISPR road: from bench to bedside on an RNA-guided path
Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort
Microbiome, a new dimension in cancer research
Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei
Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome
Irfana Muqbil, Ramzi M. Mohammad
Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?
Sarina Bains, Prasad S. Adusumilli
Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy
Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli
Radiotherapy: killing with complement
Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming
Getting to the core of fibrosis: targeting redox imbalance in aging
Louise Hecker, Victor J. Thannickal


Applications of iPSC-derived models of Gaucher disease
Daniel K. Borger, Elma Aflaki, Ellen Sidransky
The impact of sedation protocols on outcomes in critical illness
Benjamin Scott, Tobias Eckle

Review Article

Osteonecrosis of the knee: review
Ammar R. Karim, Jeffrey J. Cherian, Julio J. Jauregui, Todd Pierce, Michael A. Mont
Update in genetic susceptibility in melanoma
Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly

Original Article

Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari
Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers

Review Articles

Functional role of microvesicles in gastrointestinal malignancies
Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng
Effect of high fat-diet and obesity on gastrointestinal motility
Mazen Al Mushref, Shanthi Srinivasan
The physiological roles of secretin and its receptor
Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds
Noorjahan Panjwani

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test
Takahiro Uotani, David Y. Graham

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease
Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease
David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease
Christiane Reitz

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.



Review Article

Original Article