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Focus on “New Image Diagnostic and Therapeutic Modalities in Thoracic Surgery” More >>
Focus on “Inborn Errors of Metabolism” More >>
Focus on “Novel Aspects in Ventilator-associated Pneumonia” More >>

Endorsement

Annals of Translational Medicine is endorsed by the Bonnie J. Addario Lung Cancer Foundation (ALCF), the Ming-Yi Medical Charity Foundation of Guangdong Province, the international Inspire2Live Patient Advocates organization, and the Hellenic Cooperative Oncology Group.

Endorsement
Endorsement
Endorsement

the Brazilian Society of Thoracic Surgery(SBCT)

the Brazilian Society of Thoracic Surgery(SBCT) the Bonnie J. Addario Lung Cancer Foundation (ALCF)

Original Article

Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland
Hannes Halldorsson, Andri Wilberg Orrason, Gudrun Nina Oskarsdottir, Astridur Petursdottir, Bjorn Mar Fridriksson, Magnus Karl Magnusson, Steinn Jonsson, Tomas Gudbjartsson
Systematic identification of key genes and pathways in clear cell renal cell carcinoma on bioinformatics analysis
Zhao-Hui Tian, Cheng Yuan, Kang Yang, Xing-Liang Gao
Preoperative thromboprophylactic administration of low-molecular-weight-heparin significantly decreased the risk of intraoperative bleeding compared with heparin in patients undergoing video-assisted lobectomy for lung cancer
Gu-Ha A-Lai, Yun-Ke Zhu, Gang Li, Me-Wu-Jia Mai-Ji, Han-Yu Deng, Jun Luo, Ze-Guo Zhuo, Xu Shen, Yi-Dan Lin
Co-expression of CD44/MyD88 is a poor prognostic factor in advanced epithelial ovarian cancer
Yi Zhu, Hongtao Zhang, Guonan Zhang, Yu Shi, Jianming Huang
Mid-term outcomes of titanium modular neck femoral stems in revision total hip arthroplasty
Hervé Ouanezar, Thomas Jalaguier, Florent Franck, Vincent Pibarot, Hugo Bothorel, Mo Saffarini, Jean-Pierre Piton
Significant association of CD4+CD25+Foxp3+ regulatory T cells with clinical findings in patients with systemic lupus erythematosus
Xiaofan Yang, Weiwen Wang, Juan Xu, Ming-Shun Zhang, Huanping Mei, Youxuan Shen, Miao-Jia Zhang, Xiaohui Ji, Huijuan Wang
Association between carotid plaque and Parkinson’s disease
Lan-Yun Yan, Qing-Fang He, Min-Yan Lu, Sheng-Long Wang, Zhi-Qiang Qi, Hai-Rong Dong
Clinical significance of pretreatment tumor growth rate for locally advanced non-small cell lung cancer
Benedict Osorio, Nikhil Yegya-Raman, Sinae Kim, Charles B. Simone II, Christina Theodorou Ross, Matthew P. Deek, Dakim Gaines, Wei Zou, Liyong Lin, Jyoti Malhotra, Ke Nie, Joseph Aisner, Salma K. Jabbour
Protective effect of intraoperative re-dose of prophylactic antibiotics on surgical site infection in diabetic patients: a retrospective cohort study
Xu Zhang, Tan Li, Yan Li, Miao He, Ya-Qi Liu, Meng-Ying Wang, Shi-Jie Xin, Qun Zhao
Intermittent hypoxia enhances the tumor programmed death ligand 1 expression in a mouse model of sleep apnea
Mao-Hong Huang, Xiao-Bin Zhang, Hui-Ling Wang, Liu-Xia Li, Yi-Ming Zeng, Miao Wang, Hui-Qing Zeng
Is severe re-expansion pulmonary edema still a lethal complication of closed thoracostomy or thoracic surgery?
Sang Kwon Lee, Jung Joo Hwang, Mi Hee Lim, Joo Hyung Son, Do Hyung Kim
Probiotics improve glucose and lipid metabolism in pregnant women: a meta-analysis
Man-Man Han, Jin-Fang Sun, Xiang-Hui Su, You-Fan Peng, Hemant Goyal, Chun-Hua Wu, Xiang-Yun Zhu, Ling Li
Clinicopathological characteristics and treatment strategies for young lung cancer patients
Remi Yoneyama, Hisashi Saji, Yasufumi Kato, Yujin Kudo, Yoshihisa Shimada, Masakazu Kimura, Masaru Hagiwara, Masatoshi Kakihana, Kuniharu Miyajima, Naohiro Kajiwara, Tatsuo Ohira, Harubumi Kato, Norihiko Ikeda
Broncholithiasis: retrospect of 15 surgical treatment patients
Dongliang Bian, Peng Zhang, Huibiao Zhang, Ke Fei
Outcomes of transcatheter aortic valve replacement in bicuspid aortic valve stenosis
Tamunoinemi Bob-Manuel, Mark R. Heckle, Ikechukwu A. Ifedili, Jiajing Wang, Uzoma N. Ibebuogu
Risk factors associated with prolonged air leak after video-assisted thoracic surgery pulmonary resection: a predictive model and meta-analysis
Huiyu Pan, Ruimin Chang, Yanwu Zhou, Yang Gao, Yuanda Cheng, Chunfang Zhang
Which induction chemotherapy regimen followed by cisplatin-based concurrent chemoradiotherapy is the best choice among PF, TP and TPF for locoregionally advanced nasopharyngeal carcinoma?
Yan He, Tao Guo, Jingjing Wang, Yu Sun, Hui Guan, Shaoyong Wu, Xingchen Peng

Review Article

NK-mediated antibody-dependent cell-mediated cytotoxicity in solid tumors: biological evidence and clinical perspectives
Cristiana Lo Nigro, Marco Macagno, Dario Sangiolo, Luca Bertolaccini, Massimo Aglietta, Marco Carlo Merlano

Case Report

Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report
Laura Bender, Guillaume Meyer, Elisabeth Quoix, Bertrand Mennecier
Hemorrhagic bulla: a rare presentation of scabies
Lan-Ying Li, Hong Sun, Xiao-Ying Li, Juan-Hua Liu, Wen-Xing Liu, Di-Qing Luo
A case of recurrent hemoptysis caused by pulmonary actinomycosis diagnosed using transbronchial lung biopsy after bronchial artery embolism and a brief review of the literature
Manabu Suzuki, Kyoko Araki, Sachi Matsubayashi, Konomi Kobayashi, Eriko Morino, Jin Takasaki, Motoyasu Iikura, Shinyu Izumi, Yuichiro Takeda, Haruhito Sugiyama

Letter to the Editor

Beneficiality of levosimendan for Takotsubo syndrome remains uncertain
Josef Finsterer, Claudia Stöllberger

Editorial

Will the 40-gene expression classifier predict responders to EGFR targeted chemotherapy for the invasive bladder cancer patients?
Jayoung Kim, Wun-Jae Kim
Translating basic science discoveries to clinical practice—Let us not repeat the naiveté of the pre-omics era
Kimberly J. Payne, Abigail Benitez, Sinisa Dovat
Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?
Kevin P. Daly
Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized
Mark R. Walter
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
γδ T cells and immunity to human malaria in endemic regions
Samarchith P. Kurup, John T. Harty
Apyrase as a novel therapeutic inhibitor of heterotopic ossification
Olin D. Liang, Anthony M. Reginato, Damian Medici
The CRISPR road: from bench to bedside on an RNA-guided path
Benjamin Garcia-Bloj, Colette Moses, Pilar Blancafort
Microbiome, a new dimension in cancer research
Antonio Galvao Neto, Azore-Dee Bradshaw, Zhiheng Pei
Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome
Irfana Muqbil, Ramzi M. Mohammad
Is spread through alveolar spaces, the newly recognized pattern of invasion, a potential game changer in lung adenocarcinoma?
Sarina Bains, Prasad S. Adusumilli
Significance of IASLC/ATS/ERS classification for early-stage lung adenocarcinoma patients in predicting benefit from adjuvant chemotherapy
Yusuke Takahashi, Takashi Eguchi, Sarina Bains, Prasad S. Adusumilli
Radiotherapy: killing with complement
Jean F. Regal, Kenneth J. Dornfeld, Sherry D. Fleming
Getting to the core of fibrosis: targeting redox imbalance in aging
Louise Hecker, Victor J. Thannickal
The Art of War and oncology: applying the principles of strategy and tactics to greater effect in the era of targeted therapy
Emil Lou
Protecting functional β cells with a therapeutic peptide
Meghan L. Marré, Jon D. Piganelli, Eddie A. James
Acidosis and citrate: provocative interactions
Kathleen S. Hering-Smith, L. Lee Hamm

Commentary

Applications of iPSC-derived models of Gaucher disease
Daniel K. Borger, Elma Aflaki, Ellen Sidransky
The impact of sedation protocols on outcomes in critical illness
Benjamin Scott, Tobias Eckle

Review Article

Osteonecrosis of the knee: review
Ammar R. Karim, Jeffrey J. Cherian, Julio J. Jauregui, Todd Pierce, Michael A. Mont
Update in genetic susceptibility in melanoma
Miriam Potrony, Celia Badenas, Paula Aguilera, Joan Anton Puig-Butille, Cristina Carrera, Josep Malvehy, Susana Puig
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly
Colorectal cancer genomics and designing rational trials
Sebastian Mondaca, Rona Yaeger
Emerging application of genomics-guided therapeutics in personalized lung cancer treatment
Aubhishek Zaman, Trever G. Bivona
Aminoquinoline antimalarial therapy in dermatomyositis—are we missing opportunities with respect to comorbidities and modulation of extracutaneous disease activity?
Richard D. Sontheimer

Original Article

Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari
Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
Melissa A. Goddard, David L. Mack, Stefan M. Czerniecki, Valerie E. Kelly, Jessica M. Snyder, Robert W. Grange, Michael W. Lawlor, Barbara K. Smith, Alan H. Beggs, Martin K. Childers

Review Articles

Functional role of microvesicles in gastrointestinal malignancies
Kelly McDaniel, Robert Correa, Tianhao Zhou, Christopher Johnson, Heather Francis, Shannon Glaser, Julie Venter, Gianfranco Alpini, Fanyin Meng
Effect of high fat-diet and obesity on gastrointestinal motility
Mazen Al Mushref, Shanthi Srinivasan
The physiological roles of secretin and its receptor
Syeda Afroze, Fanyin Meng, Kendal Jensen, Kelly McDaniel, Kinan Rahal, Paolo Onori, Eugenio Gaudio, Gianfranco Alpini, Shannon S. Glaser

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds
Noorjahan Panjwani

Helicobacter Pylori

Diagnosis of Helicobacter pylori using the rapid urease test
Takahiro Uotani, David Y. Graham

Review Article on MicroRNAs, Signalling Pathways and Diseases

MicroRNAs in congenital heart disease
Tanya Smith, Cha Rajakaruna, Massimo Caputo, Costanza Emanueli

Review Article on Toward Precision Medicine in Neurological Diseases

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease
David D. Bushart, Geoffrey G. Murphy, Vikram G. Shakkottai

Focus on Toward Precision Medicine in Neurological Diseases

Toward precision medicine in Alzheimer’s disease
Christiane Reitz

Editorial on Cardiovascular Disease and Cardiometabolic Risk: Advances in Understanding Pathophysiology, Public Health Burden and Clinical Care

Advances in resistant hypertension
David A. Calhoun

Below are the latest Annals of Translational Medicine articles published online ahead of print publication.

Editorial Commentary