Vol 5, No 24 (December 2017): Annals of Translational Medicine

Original Article

Evaluation bias in objective response rate and disease control rate between blinded independent central review and local assessment: a study-level pooled analysis of phase III randomized control trials in the past seven years
Jianrong Zhang, Yiyin Zhang, Shiyan Tang, Hengrui Liang, Difei Chen, Long Jiang, Qihua He, Yu Huang, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen, Wenhua Liang, Jianxing He
Temporal trends and outcomes of acute myocardial infarction in patients with cancer
Naga Venkata Pothineni, Nishi N. Shah, Yogita Rochlani, Marwan Saad, Swathi Kovelamudi, Konstantinos Marmagkiolis, Sabha Bhatti, Mehmet Cilingiroglu, Wilbert S. Aronow, Abdul Hakeem

Review Article

The management of a blood donor bitten by a snake
Giuseppe Marano, Massimo Franchini, Liviana Catalano, Stefania Vaglio, Simonetta Pupella, Giancarlo M. Liumbruno

Big-data Clinical Trial Column1

Comparing baseline characteristics between groups: an introduction to the CBCgrps package
Zhongheng Zhang, Alberto Alexander Gayle, Juan Wang, Haoyang Zhang, Pablo Cardinal-Fernández
Rainforest plots for the presentation of patient-subgroup analysis in clinical trials
Zhongheng Zhang, Michael Kossmeier, Ulrich S. Tran, Martin Voracek, Haoyang Zhang


Unravelling the mysterious onchocerciasis-nodding syndrome link: new developments and future challenges
Angelina Kakooza-Mwesige
On predicting clinical response to chemoradiotherapy in esophageal squamous cell carcinoma: additional evaluation by magnetic resonance imaging may help
Ta-Chen Huang, Chih-Hung Hsu
Challenges of quitting smoking and lung cancer screening
Giulia Carreras, Giuseppe Gorini
Tissue-nonspecific alkaline phosphatase: a promising target for pseudoxanthoma elasticum therapy
András Váradi,, Krisztina Fülöp, Tamás Arányi, Flóra Szeri
Transfer of altered behaviour and irritable bowel syndrome with diarrhea (IBS-D) through fecal microbiota transplant in mouse model indicates need for stricter donor screening criteria
Laura J. Craven, Michael Silverman, Jeremy P. Burton
Coronary artery bypass grafting versus percutaneous coronary intervention in complex coronary artery disease: looking beyond clinical end-points
Aakash Garg, Hitesh Raheja, Marc Cohen
Always hard to absorb: youngsters suicide from childhood adversity
Jianrong Zhang
Message from “real-world” data of transcatheter versus surgical aortic valve replacement
Tomo Ando, Luis Afonso
Ezh2-dependent therapies in bladder cancer: synthetic lethality
Cristina Segovia, Jesús M. Paramio
Insight from a large real-world cohort of patients: does it confirm the results of the randomized trials?
Nils Perrin, Stéphane Noble
The impact of thoracic endovascular aortic repair on long-term survival in type B aortic dissection
Christos D. Karkos, Ignacio Hernandez-Lahoz, Nikolaos Asaloumidis, Konstantinos O. Papazoglou
Antiangiogenic therapy and immune checkpoint blockade go hand in hand
Luis Felipe Campesato, Taha Merghoub
Is there a long-term survival benefit with on pump coronary artery bypass grafting?
Nicola King
Geospatial modelling in guiding health program strategies in resource-limited settings—the way forward
Diane Gu, Chawangwa Modongo, Sanghyuk S. Shin, Nicola M. Zetola
Switch-on the LAMP to spot Zika
Erick Mora-Cárdenas, Alessandro Marcello
Profiling of plasma-derived extracellular vesicles cargo for diagnosis of pancreatic malignancy
Theresa L. Whiteside
Surrogate end points in early prostate cancer clinical states: ready for implementation?
Christos E. Kyriakopoulos, Emmanuel S. Antonarakis
Definitive chemoradiation for resectable carcinoma of the cervical esophagus: do we need more evidence?
Antoine Adenis, Guillaume Piessen, David Azria
Poly(GP) proteins: a potential pharmacodynamic marker in ALS and FTD
Mauricio Budini, Alfredo Criollo
Semaglutide seems to be more effective the other GLP-1Ras
Jens Juul Holst, Sten Madsbad
Fecal microbiota transplantation as a possible treatment of irritable bowel syndrome
Anna C. Juncadella, Alan Moss
Editorial on “An automated smartphone-based diagnostic assay for point-of-care semen analysis”
Sarah Coleman Vij, Ashok Agarwal
Improving deep brain stimulation: timing makes all the difference
Jan Hirschmann, Alfons Schnitzler

Letter to the Editor

Diamonds are for men, too
Andrei P. Sommer


1. The series “Big-data Clinical Trial Column” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.