Vol 6, No 3 (February 2018): Annals of Translational Medicine

Review Article

Microscopic colitis—microbiome, barrier function and associated diseases
Saskia van Hemert, Karolina Skonieczna-Żydecka, Igor Loniewski, Piotr Szredzki, Wojciech Marlicz
Thoracic perforations—surgical techniques
Atilla Eroglu, Yener Aydin, Omer Yilmaz
Peculiarities of intra-thoracic colon interposition—eso-coloplasty: indications, surgical management and outcomes
Lucile Gust, Henri De Lesquen, Ilies Bouabdallah, Geoffrey Brioude, Pascal-Alexandre Thomas, Xavier-Benoit D’journo

Big-data Clinical Trial Column2

Variable selection in Logistic regression model with genetic algorithm
Zhongheng Zhang, Victor Trevino, Sayed Shahabuddin Hoseini, Smaranda Belciug, Arumugam Manivanna Boopathi, Ping Zhang, Florin Gorunescu, Velappan Subha, Songshi Dai
Tutorial: development of an online risk calculator platform
Xinge Ji, Michael W. Kattan


Secondary analysis of electronic health records in critical care medicine
Sven Van Poucke, Alberto Alexander Gayle, Milan Vukicevic
LAMP assay for specific detection of Asian and African lineage Zika virus: will it meet the expectations?
Yaniv Lustig, Danit Sofer, Musa Hindiyeh, Ella Mendelson
CMTM6 stabilizes PD-L1 expression and refines its prognostic value in tumors
Emilie Mamessier, David J. Birnbaum, Pascal Finetti, Daniel Birnbaum, François Bertucci
Sodium-glucose cotransporter-2 inhibitors and cardiovascular outcomes: insights from the CVD-REAL study
Marwan Saad
Protease activated receptor 4: a backup receptor or a dark horse as a target in antiplatelet therapy?
Xu Han, Marvin T. Nieman
Osimertinib in first-line treatment—is a comparison not proof?
Jacques Cadranel
New insight into type 1 diabetes development: resolving early diabetogenic CD4+ T cell responses that precede seroconversion
Sonja Schallenberg, Karsten Kretschmer
Geospatial mapping to identify feasible HIV prevention and treatment strategies that target specific settings
Paula M. Frew, Chelsea S. Lutz, Ighovwerha Ofotokun, Vincent C. Marconi, Carlos del Rio
Lowering low-density lipoprotein cholesterol by PCSK9 inhibition in patients with diabetes on insulin therapy: is it efficacious and safe?
Michel Farnier
Osimertinib, the winner, but cannot yet take it all
Shinkyo Yoon, Jihoon Kang, Dae Ho Lee
First-line osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer
Byeong-Ho Jeong, Sang-Won Um
Insulin degludec U100 is associated with lower risk for severe and symptomatic hypoglycemia as compared with insulin glargine U100 in subjects with type 1 diabetes
Anastasios Tentolouris, Ioanna Eleftheriadou, Nikolaos Tentolouris
MucoJet: a novel noninvasive buccal mucosa immunization strategy
Hetron Mweemba Munang’andu
Risk models to select high risk candidates for lung cancer screening
Matthew B. Schabath
Treatment of thoracic aortic aneurysm
Wilbert S. Aronow


1. The series “Column in Hypertension” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

2. The series “Big-data Clinical Trial Column” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

3. The series “Meet the Professor” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.