Vol 6, No 19 (October 2018): Annals of Translational Medicine (Focus on “Respiratory Mechanics in Mechanically Ventilated Patients with and without Lung injury”)

Review Article

The basics of respiratory mechanics: ventilator-derived parameters
Pedro Leme Silva, Patricia R. M. Rocco
Technical aspects of bedside respiratory monitoring of transpulmonary pressure
Francesco Mojoli, Francesca Torriglia, Anita Orlando, Isabella Bianchi, Eric Arisi, Marco Pozzi
Ventilator-induced lung injury and lung mechanics
Jason H. T. Bates, Bradford J. Smith
Respiratory mechanics during general anaesthesia
Lorenzo Ball, Federico Costantino, Martina Fiorito, Sara Amodio, Paolo Pelosi
Mechanical ventilation management during cardiothoracic surgery: an open challenge
Elena Bignami, Francesco Saglietti, Antonio Di Lullo
Management and weaning from mechanical ventilation in neurologic patients
Raphaël Cinotti, Marwan Bouras, Antoine Roquilly, Karim Asehnoune
Respiratory mechanics in patients with acute respiratory distress syndrome
Vincenzo Russotto, Giacomo Bellani, Giuseppe Foti
Interpretation of the transpulmonary pressure in the critically ill patient
Michele Umbrello, Davide Chiumello
Effects of patient positioning on respiratory mechanics in mechanically ventilated ICU patients
Mehdi Mezidi, Claude Guérin
Regional distribution of transpulmonary pressure
Pedro Leme Silva, Marcelo Gama de Abreu
Mechanical ventilation and respiratory monitoring during extracorporeal membrane oxygenation for respiratory support
Nicolò Patroniti, Giulia Bonatti, Tarek Senussi, Chiara Robba
Assessing breathing effort in mechanical ventilation: physiology and clinical implications
Heder de Vries, Annemijn Jonkman, Zhong-Hua Shi, Angélique Spoelstra-de Man, Leo Heunks
Dead space in acute respiratory distress syndrome
Massimo Ferluga, Umberto Lucangelo, Lluis Blanch
Should we titrate ventilation based on driving pressure? Maybe not in the way we would expect
Paolo Pelosi, Lorenzo Ball


Is the mechanical power the final word on ventilator-induced lung injury?—we are not sure
Francesco Vasques, Eleonora Duscio, Iacopo Pasticci, Federica Romitti, rancesco Vassalli, Michael Quintel, Luciano Gattinoni


The focused issue “Respiratory Mechanics in Mechanically Ventilated Patients with and without Lung injury” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding. Paolo Pelosi and Lorenzo Ball served as the unpaid Guest Editors for the focused issue.