Tranexamic acid and total hip arthroplasty: optimizing the administration method

Jean-Edern Ollivier, Stéphane Van Driessche, Fabien Billuart, Julien Beldame, Jean Matsoukis


Total hip arthroplasty (THA) is associated with significant peri-operative bleeding that can cause hematomas and sometimes acute anemia requiring blood transfusion with potential risks and costs. Theses complications will delay a patient’s functional recovery and discharge. Blood-sparing strategies are one element of the rapid recovery protocols used for joint replacement surgery. Tranexamic acid (TXA) has its rightful place in this context.