Article Abstract

The interplay between genetics, epigenetics and environment in modulating the risk of coronary heart disease

Authors: Giuseppe Lippi, Gianfranco Cervellin

Abstract

In the second decade of the 21st century, coronary heart disease (CHD) remains the leading cause of morbidity and mortality worldwide (1). Despite the overall prevalence of this condition has favourably declined over the last 10 years, the death rate remains high, accounting for approximately 1 of every 7 deaths in the United States (2), thus paving the way to additional research aimed at identifying reliable means of prevention and clinical management.