@article{ATM9241,
author = {Atreyee Basu and Shashi Seth and Ashok K. Chauhan and Nupur Bansal and Kanchan Arora and Anuradha Mahaur},
title = {Comparative study of tumor markers in patients with colorectal carcinoma before and after chemotherapy},
journal = {Annals of Translational Medicine},
volume = {4},
number = {4},
year = {2016},
keywords = {},
abstract = {Background: Colorectal carcinoma (CRC), the second leading cause of cancer-related deaths in US, has a rising time-trend in India. Tumour markers in CRC are extensively researched, and there’s still debate on their diagnostic and prognostic values.
Methods: In this hospital-based longitudinal study in north India, 51 male diagnosed CRC cases (pre-chemotherapy) were contrasted against 50 age and sex matched controls. Nine biomarkers: carcinoembryonic antigen (CEA), prolactin (PRL), alfa feto protein (AFP), total human chorionic gonadotropin (hCG), cancer antigen-125 (CA-125), serum testosterone, prostate specific antigen (PSA) and ferritin were measured by direct chemiluminescence technique. Further, follow-up was done on 47 cases after treatment with six cycles of 5-flurouracil (5-FU) and oxaliplatin.
Results: Mean serum CEA (case: 5.94±8.27 ng/mL, control: 2.5±0.79 ng/mL, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/9241}
}