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Pre-treatment systemic immune-inflammation represents a prognostic factor in patients with advanced non-small cell lung cancer

  
@article{ATM29653,
	author = {Rossana Berardi and Matteo Santoni and Silvia Rinaldi and Marc Bower and Michela Tiberi and Francesca Morgese and Miriam Caramanti and Agnese Savini and Consuelo Ferrini and Mariangela Torniai and Ilaria Fiordoliva and Thomas Newsom-Davis},
	title = {Pre-treatment systemic immune-inflammation represents a prognostic factor in patients with advanced non-small cell lung cancer},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {20},
	year = {2019},
	keywords = {},
	abstract = {Background: Inflammation plays an important role in pathogenesis, development and progression of lung cancer. The aim of the study is to assess the prognostic role of Systemic Immune-Inflammation Index (SII), obtained by analyzing the neutrophil, lymphocyte and platelet counts, and to design prognostic models for patients receiving first-line chemo- or targeted therapy for advanced non-small cell lung cancer (NSCLC). 
Methods: We conducted an analysis on 311 patients with advanced NSCLC, treated with first line chemoor targeted therapy till June 2015 at our Institution. Patients were stratified in two groups with SII ≥1,270 (Group A) vs. SII },
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/29653}
}