Vol 6, No 11 (June 2018): Annals of Translational Medicine

Original Article

Blood pressure targets for hypertension in patients with type 2 diabetes
Wilbert S. Aronow, Tatyana A. Shamliyan
Trends of snowboarding-related fractures that presented to emergency departments in the United States, 2010 to 2016
Aleksey Seleznev, Neil V. Shah, Rohan Desai, Cuong Le, Patrick Cleary, Qais Naziri, Niladri N. Basu, Barbara J. Freeman, William P. Urban, Jared M. Newman
The efficacy of first-line chemotherapy in recurrent or metastatic nasopharyngeal carcinoma: a systematic review and metaanalysis
Shu-Xiang Ma, Ting Zhou, Yan Huang, Yun-Peng Yang, Jian-Hua Zhan, Ya-Xiong Zhang, Zhong-Han Zhang, Yuan-Yuan Zhao, Wen-Feng Fang, Yu-Xiang Ma, Li-Kun Chen, Hong-Yun Zhao, Li Zhang
Cervical or thoracic anastomosis for patients with cervicothoracic esophageal squamous cell carcinoma
Ran Mo, Chen Chen, Liang Pan, Ao Yu, Tao Wang
Compensatory hyperhidrosis after different surgeries at the same sympathetic levels: a meta-analysis
Xiaojun Du, Xu Zhu, Tao Wang, Xiao Hu, Peng Lin, Yin Teng, Chao Fan, Jianglun Li, Yang Xi, Jiarong Xiao, Wen Liu, Jian Zhang, Haiyu Zhou, Dan Tian, Shizhang Yuan
Short-term outcomes for total knee arthroplasty patients with active extension lag
Tanner L. McGinn, Jennifer I. Etcheson, Chukwuweike U. Gwam, Nicole E. George, Nequesha S. Mohamed, Jaydev B. Mistry, Ugochi Ananaba, Anil Bhave
Physical activity levels are low in patients with pulmonary hypertension
Laura González-Saiz, Alejandro Santos-Lozano, Carmen Fiuza-Luces, Paz Sanz-Ayán, Carlos A. Quezada-Loaiza, Ana Ruiz-Casado, Lidia B. Alejo, Angela Flox-Camacho, María Morán, Alejandro Lucia, Pilar Escribano-Subías
Impact of polymyxin B hemoperfusion in the treatment of patients with sepsis and septic shock: a meta-analysis of randomized controlled trials
Akira Kuriyama, Morihiro Katsura, Seigo Urushidani, Tadaaki Takada
Increasing clinical resistance rate of Shigella sonnei to cefotaxime in Jiangsu Province, China, between 2012 and 2015
Huimin Qian, Guoye Liu, Yin Chen, Ping Ma, Xiaoxiao Kong, Lu Zhou, Jie Hong, Changjun Bao, Bing Gu
Study on factors affecting local peak strain results in automatic functional imaging of transthoracic echocardiography
Na Li, Linbin Meng, Yichen Wang, Kailing Xiong, Junxuan He, Yang Wang, Yifu Qiao, Attila Nemes, Raffaele Giordano, Lang Qiao, written on behalf of AME Echocardiography Collaborative Group
miR-486 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells
Jin Li, Qiulian Zhou, Yajun Liang, Wen Pan, Yihua Bei, Yuhui Zhang, Jinhua Wang, Zheng Jiao

Review Article

Surgery for intrathoracic tracheoesophageal and bronchoesophageal fistula
Benoit Jacques Bibas, Paulo Francisco Guerreiro Cardoso, Helio Minamoto, Paulo Manoel Pêgo-Fernandes

Surgical Technique

Development and clinical applications of glasses-free three-dimensional (3D) display technology for thoracoscopic surgery
Jun Liu, Fei Cui, Jingpei Li, Wenlong Shao, Wei Wang, Jun Li, Muchun Liu, Jianxing He

Technical Note

Laparoscopic suture training curricula and techniques
Xin Wang, Yongbin Li, Yunqiang Cai, Lingwei Meng, He Cai, Xubao Liu, Bing Peng

Big-data Clinical Trial Column1

Opening the black box of neural networks: methods for interpreting neural network models in clinical applications
Zhongheng Zhang, Marcus W. Beck, David A. Winkler, Bin Huang, Wilbert Sibanda, Hemant Goyal, written on behalf of AME Big-Data Clinical Trial Collaborative Group


Aspirin and diabetes mellitus in primary prevention: the Endless Conundrum
Rubén Casado-Arroyo
Low-dose aspirin for primary cardiovascular prevention in diabetic patients: the issue to believe it or not
Priscilla Lamendola, Angelo Villano, Augusto Fusco, Massimo Leggio
Quality of life and treatment satisfaction are highly relevant patient-reported outcomes in type 2 diabetes mellitus
Didac Mauricio
Multi-drug therapy in breast cancer: are there any alternatives?
Partha Mitra
Which criteria should we use to evaluate the efficacy of immunecheckpoint inhibitors?
Yuki Kataoka, Katsuya Hirano
An important piece of the puzzle for understanding the benefits of concomitant ablation of atrial fibrillation in cardiac surgery
Anders Albåge
Policy and governance solutions for ensuring equitable access to cancer medicines in low- and middle-income countries
Raphael E. Cuomo, Tim K. Mackey
The uremic solute-AHR-tissue factor axis in vascular cells, mouse models and thrombosis in chronic kidney disease patients
Nigel Mackman, Jonathan H. Erlich
Is effective the hyperbaric oxygen therapy for the treatment of ischemic lower extremity ulcers?—new insights from a multicenter study
Bruno Rivas-Santiago
Building a cultural alliance for the prevention of fragility fractures among high risk older adults
Marta Baroni, Valentina Prenni, Carmelinda Ruggiero
Hyperbaric oxygen for treatment of diabetic foot ulcers: love you more than I can say
Qinan Wu
Optimal regimen of cisplatin in squamous cell carcinoma of head and neck yet to be determined
Xiuning Le, Ehab Y. Hanna
Gene-expression signature may be useful for the prediction of lymph node metastasis in esophageal cancer
Yoshifumi Baba, Hideo Baba
The search for surrogate endpoints for immunotherapy trials
Marc Buyse, Tomasz Burzykowski, Everardo D. Saad
BLU-285—the breakthrough in treatment of patients with aggressive systemic mastocytosis and gastrointestinal stromal tumor
Regine Schneider-Stock
Noninvasive cancer biomarkers in solid malignancies: circulating tumor DNA—clinical utility, current limitations and future perspectives
Debora de Melo Gagliato, Denis L. Fontes Jardim
Unmask the genetic backbone of ibrutinib-relapsed chronic lymphocytic leukemia progression and Richter transformation
Wei-Ge Wang, Xiao-Yan Zhou, Xiao-Qiu Li
The promise and challenges of chimeric antigen receptor T cells in relapsed B-cell acute lymphoblastic leukemia
Zhi-Chun Ding
Different prevalence and clinical outcome of Epstein-Barr virus positive diffuse large B-cell lymphoma between North American and non-Western populations
Lihui Yin, Zijun Y. Xu-Monette, Jay Brock, Yong Li, Ken H. Young
Revolutionary changes in salvage treatment for Hodgkin lymphoma: toward a chemotherapy-free future
Jiawen Chen, Wei Yang, Zimu Gong
Is there a place for the combination of brentuximab vedotin and bendamustine in treatment of patients with relapsed/refractory Hodgkin lymphoma?
Robert W. Chen


1. The series “Big-data Clinical Trial Column” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

2. The series “Column in Changemakers in Patient-Oriented Translational Clinical Investigation” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.