Vol 6, No 10 (May 2018): Annals of Translational Medicine (Focus on “Translational Neurodegeneration”)

Original Article on Translational Neurodegeneration1

Meta-analysis of the association between CD33 and Alzheimer’s disease
Yu-Ting Jiang, Hai-Yan Li, Xi-Peng Cao, Lan Tan
The expression of KATP channel subunits in alpha-synucleintransfected MES23.5 cells
Shuai-Shuai Han, Qian Jiao, Ming-Xia Bi, Xi-Xun Du, Hong Jiang
The impact of GAB2 genetic variations on cerebrospinal fluid markers in Alzheimer’s disease
Xiao-Xiao Chen, Run-Rong Guo, Xi-Peng Cao, Lin Tan, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative
Association of lectin-like oxidized low density lipoprotein receptor 1 (OLR1) polymorphisms with late-onset Alzheimer disease in Han Chinese
Zuo-Teng Wang, Xiao-Ling Zhong, Meng-Shan Tan, Hui-Fu Wang, Chen-Chen Tan, Wei Zhang, Zhan-Jie Zheng, Ling-Li Kong, Lan Tan, Li Sun
Characterization of the locomotor activities of zebrafish larvae under the influence of various neuroactive drugs
Fei Li, Jia Lin, Xiuyun Liu, Wenhui Li, Yifeng Ding, Yunjian Zhang, Shuizhen Zhou, Ning Guo, Qiang Li
Adult-onset Krabbe disease in two generations of a Chinese family
Tongxia Zhan, Chuanzhu Yan, Kunqian Ji, Pengfei Lin, Lingyi Chi, Xiuhe Zhao, Yuying Zhao

Review Article on Translational Neurodegeneration1

Tau in neurodegenerative disease
Yong-Lei Gao, Nan Wang, Fu-Rong Sun, Xi-Peng Cao, Wei Zhang, Jin-Tai Yu
Microglial priming in Alzheimer’s disease
Jun-Wei Li, Yu Zong, Xi-Peng Cao, Lin Tan, Lan Tan
Innate immune activation in Alzheimer’s disease
Ming-Ming Wang, Dan Miao, Xi-Peng Cao, Lin Tan, Lan Tan
The role of UNC5C in Alzheimer’s disease
Quan Li, Bai-Ling Wang, Fu-Rong Sun, Jie-Qiong Li, Xi-Peng Cao, Lan Tan

Surgical Technique

Resection of esophageal diverticulum through uniportal video-assisted thoracoscopic surgery
Alfonso Fiorelli, Anna Cecilia Izzo, Ettore Arrigo, Francesco Sgalambro, Maria Antonietta Lepore, Massimo Cajozzo, Sergio Castorina, Attilio Ignazio Lo Monte, Mario Santini, Francesco Paolo Caroni

Big-data Clinical Trial Column3

Instrumental variable analysis in the presence of unmeasured confounding
Zhongheng Zhang, Md Jamal Uddin, Jing Cheng, Tao Huang


Aortic valve replacement in young patients: should the biological prosthesis be recommended over the mechanical?
Alberto Alperi, Daniel Hernandez-Vaquero, Isaac Pascual, Rocio Diaz, Iria Silva, Ruben Alvarez-Cabo, Pablo Avanzas, Cesar Moris
The choice of heart valve prosthesis for aortic valve replacement in the young: about choices and consequences
Thierry Bove
Bioprosthetic aortic valve replacement: a telltale from the young
Athanasios Antoniou, Amer Harky, John Yap, Kulvinder Kulvinder Lall, Mohamad Bashir
Can we exonerate GLP-1 receptor agonists from blame for adverse pancreatic events?
Conor F. Murphy, Carel W. le Roux
Translating patient related outcome measures into practice— lessons to be learnt
Waseem Majeed, Hood Thabit
Does continuous glucose monitoring during pregnancy improve glycaemic and health outcomes in women with type 1 diabetes?— what the CONCEPTT trial adds
Diane Farrar, Matthew D. Campbell
Improved outcome of bilateral compared to single internal thoracic artery grafting: patient’s selection or technical skill?
Antonio M. Calafiore, Carlo Maria De Filippo, Massimiliano Foschi, Michele Di Mauro
Untangling the bilateral versus single internal mammary coronary artery bypass grafting debate
Emile Voisine, Pierre Voisine
BPI fold-containing family a member 2 as a biomarker of acute kidney injury—close but no (clinical) cigar?
Patrick M. Honore, David De Bels, Herbert D. Spapen
Pioglitazone and cardiovascular risk in T2DM patients: is it good for all?
Muhammad Abdul-Ghani, Amin Jayyous, Nidal Asaad, Sherif Helmy, Jassim Al-Suwaidi
AdDIT Editorial comment—challenges in medication treatment of renal and cardiovascular diseases and risk factors in adolescents with type 1 diabetes
Fariba Ahmadizar, Anke H. Maitland-van der Zee
The role of glucagon-like peptide-1 receptor agonists in cardiovascular disease prevention in type 2 diabetes mellitus: evidence from the most recent clinical trials
S. John Weisnagel
Anti-diabetic agents and heart health: how to use new diabetes medications in a global strategy for the prevention of cardiovascular complications in type 2 diabetes
Carmine Gazzaruso, Adriana Coppola, Tiziana Montalcini, Colomba Falcone


1. The series “Translational Neurodegeneration” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

2. The series “Column in Laboratory Medicine” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.

3. The series “Big-data Clinical Trial Column” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding.