Vol 4, Supplement 1 (October 2016): Annals of Translational Medicine


The hunt for fatal myocardial infarction biomarkers: predictive circulating microRNAs
Francesco Russo, Milena Rizzo, Kirstine Belling, Søren Brunak, Lasse Folkersen
Acquisition of carbapenem-resistant Acinetobacter baumannii in the intensive care unit: just a question of time?
Ahmed Elkalioubie, Saad Nseir
Another promise against ischemia reperfusion injury: every success raises new questions
Dennis V. Cokkinos Dennis V. Cokkinos
Live-attenuated vaccination increases the diversity of pathogen-specific T cell repertoire triggered in chronic infection responses
Alexandre Morrot
Immunotherapy in small-cell lung cancer: at what point are we?
Antonio Rossi
Is macitentan not a treatment option for digital ulcers in systemic sclerosis?
Yoshihide Asano
The AMPK-SKP2-CARM1 axis links nutrient sensing to transcriptional and epigenetic regulation of autophagy
Ziheng Xu, Daniel J. Klionsky
Sofosbuvir and velpatasvir: a stellar option for patients with decompensated hepatitis C virus (HCV) cirrhosis
Joel V. Chua, Shyam Kottilil
Immune checkpoint inhibition in patients with brain metastases
Tanner Johanns, Saiama N. Waqar, Daniel Morgensztern
Osteoporosis and strontium-substituted hydroxyapatites
Nikolaos Kourkoumelis
Na+ homeostasis by epithelial Na+ channel (ENaC) and Nax channel (Nax): cooperation of ENaC and Nax
Yoshinori Marunaka, Rie Marunaka, Hongxin Sun, Toshiro Yamamoto, Narisato Kanamura, Akiyuki Taruno
C-WORTHY: the beginning of the rise of elbasvir and grazoprevir for the treatment of hepatitis C genotype 1 mono and HIV co-infected patients
Dost Sarpel, Douglas T. Dieterich
Grazoprevir plus elbasvir and other treatment options in hepatitis C infected patients with stage 4–5 chronic kidney disease
Kalyan Ram Bhamidimarri
ASSURE vs. S-TRAC: conflicting results of adjuvant treatments for kidney cancer in the era of targeted agents and genomics
Camillo Porta, Silvia Chiellino
A liberal glycemic target in critically ill patients with poorly controlled diabetes?
Jan Gunst, Greet Van den Berghe
Can xerostomia be further reduced by sparing parotid stem cells?
Avraham Eisbruch
Transapical beating-heart mitral valve repair using a cordal implantation device—are we ready to open our minds?
Talal Al-Atassi, Vinod H. Thourani
The role of glutamate transport and SLC7A11 expression in tumor-associate seizures and survival in patients with malignant gliomas
Joseph R. Keen, Sharon A. Swanger, Stephen F. Traynelis, Jeffrey J. Olson
Modifying therapy in patients with advanced Hodgkin’s lymphoma by integrating early metabolic response by interim PET-CT
Ulrike Bacher, Mascha Binder
A canine model for neuronal ceroid lipofuscinosis highlights the promise of gene therapy for lysosomal storage diseases
Jonathan E. Phillips, Richard H. Gomer
The Ross procedure is under-used although long-term results show superior results to those obtained following mechanical aortic valve replacement
Thierry Carrel
Hospital-acquired pneumonia and community-acquired pneumonia: two guys?
Thomas Tschernig
Connecting enterovirus infection to dystrophin dysfunction in dilated cardiomyopathy
Qiongling Wang, Xander H. T. Wehrens
Tumor vaccines and cellular immunotherapies
John Nemunaitis, Neil Senzer, Leah Plato
Measuring soluble CD40 ligand: it is a fancy prognostic biomarker in STEMI-patients?
Alberto Dominguez-Rodriguez
The case for preoperative aspirin administration in patients undergoing elective CABG: is it open or closed?
Regina Kayse, Richard C. Becker
Interventional therapies in ischemic ventricular dysfunction: facts and versions!
Paulo Cury Rezende, Diogo Freitas Cardoso de Azevedo, Whady Hueb
Towards a cure for Fibrodysplasia ossificans progressiva
Gonzalo Sanchez-Duffhues, David J. J. de Gorter, Peter ten Dijke
Narcolepsy and influenza vaccination—the inappropriate awakening of immunity
Anoma Nellore, Troy D. Randall
Circulating micro ribonucleic acids in cardiovascular disease: a look beyond myocardial injury
Johannes Mair


Afatinib plus chemotherapy versus chemotherapy alone after progression on afatinib: new insights on old question?
Priyanka Bhateja, Neelesh Sharma
Rhythm is a dancer: the immediate management of postoperative atrial fibrillation following cardiac surgery
Martin I. Sigurdsson, Simon C. Body
Branching pattern of the lateral femoral cutaneous nerve at the proximal thigh: a commentary on a recent published cadaveric study
Yasuhiro , Homma, Yu Ozaki
Continuing aspirin before coronary artery bypass grafting surgery: old fears challenged by new evidences
Massimo Chello, Antonio Nenna
The prostate-specific protein, transglutaminase 4 (TG4), is an autoantigen associated with male subfertility
Siiri E. Iismaa
Should trochanteric osteotomy be always avoided during safe hip dislocation?
Alessandro Aprato, Chiara Baroni, Alessandro Massè
The anterolateral ligament: a closed chapter?
Willem A. Kernkamp, Guoan Li, Samuel K. Van de Velde
Circulating fibrocytes serve as a marker for clinical diagnosis
Thuy Cao, Sheeja Rajasingh, Johnson Rajasingh
Robotics accuracy in orthopaedics: is it enough for a well-working knee replacement?
Francesco Mancuso, Hemant Pandit
Robotic unicondylar knee arthroplasty: a commentary on a recently published level 1 study
Alexander H. Jinnah, Ashley Multani, Riyaz H. Jinnah, Johannes F. Plate
The potential of anti-VEGF (Vasotide) by eye drops to treat proliferative retinopathies
Jennifer L. Wilkinson-Berka, Devy Deliyanti
The emerging role of sST2 blocking in the therapy of graft-versus-host disease
Yifan Xiao, Fang Zheng
Time to progression ratio: promising new metric or just another metric?
Ming-Wen An, Sumithra J. Mandrekar
PTK2/FAK: a new predictive biomarker for response to radiotherapy in head and neck squamous cell carcinoma
Emma J. de Ruiter, Stefan M. Willems
Azoramide: a new drug for the treatment of type 2 diabetes?
Carlos Guillen
Severe ischemic cardiomyopathy—a new answer in management?
Brian C. Case, Monvadi B. Srichai
Vasopressin versus noradrenaline as initial therapy in septic shock. Is vasopressin-related renal protection doomed to “vanish” in the haze?
Patrick M. Honore, Rita Jacobs, Elisabeth De Waele, Inne Hendrickx, Herbert D. Spapen
Statins barely touch the heart but bite the kidneys after cardiac surgery. Coenzyme Q10 deficiency in the dock?
Patrick M. Honore, Rita Jacobs, Inne Hendrckx, Herbert D. Spapen
Less invasive approach in knee arthroplasty: everybody on board?
Guilherme Moreira Abreu-e-Silva, Thiago Scherr Dias, Marco Antônio Percope de Andrade
Collagen and fibronectin: threads linking obesity and breast cancer
Lesley G. Ellies
Playing with nanoparticle shapes and laser powers to decide which route to take during photothermal therapy: apoptosis or necrosis?
Claudia Tortiglione, Roberta Iachetta
Hybrid approach to multivessel coronary artery disease: a commentary
Alberto Repossini
Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation
Didier Bouscary
Magnetic resonance imaging-guided stratified selection of patients for nano-therapy
Zhen Zheng, Gaolin Liang
Ischemia-reperfusion injury: evidences for translational research
Francesco Bellanti
Cross-talk between cancer-initiating cells and immune cells: considerations for combination therapies
Amy S. Codd, Saly Al-Taei, Zsuzsanna Tabi
A sensible approach to targeting STAT3-mediated transcription
Neil E. Bhola, Daniel E. Johnson, Jennifer R. Grandis
Preclinical randomized controlled multicenter trials in translational stroke research
Sergio Amaro, Laura Llull
Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes
Jason P. Lynch, Manuel A. Ferreira, Simon Phipps
Circulating extracellular vesicles containing miRNAs may have utility as early biomarkers for cardiac injury
Bethany Doran, Deepak Voora
Precision medicine with electronic medical records: from the patients and for the patients
Losiana Nayak, Indrani Ray, Rajat K. De
Epidermal growth factor as a prognostic biomarker in chronic kidney diseases
Yoshitaka Isaka
Therapeutic illusion: another frontier in Ménière’s disease
Nicolas Pérez-Fernández, Eduardo Martín-Sanz
Application of liquid biopsies to identify genomic factors associated with therapy resistance in castration resistant prostate cancer
Daniel J. Crona, Young E. Whang
Second line treatment of small cell lung cancer: more is better?
Michael S. Humeniuk, Michael John Kelley
Has moderate ischemic mitral regurgitation to be corrected?—Analysis of a randomized trial
Antonio Maria Calafiore, Sotiris Prapas, Walid Abukoudair, Michele Di Mauro
Did the beneficial renal outcomes with vasopressin VANISH?
Gretchen L. Sacha, Simon W. Lam, Seth R. Bauer
The state of the art in prediction of breast cancer relapse using cell-free circulating tumor DNA liquid biopsies
Niklas Loman, Lao H. Saal


The supplement was published without any sponsorship or funding.