Vol 4, No 14 (July 2016): Annals of Translational Medicine (Immunotherapy in cancer: the clinical impact of immune response and targeting)


Overview of advances in cancer immunotherapy
Vassiliki Kotoula, George Fountzilas

Review Article

Harnessing the immune system to improve cancer therapy
Nikos E. Papaioannou, Ourania V. Beniata, Panagiotis Vitsos, Ourania Tsitsilonis, Pinelopi Samara
Neoantigen-based cancer immunotherapy
Sara Bobisse, Periklis G. Foukas, George Coukos, Alexandre Harari
Towards tumor immunodiagnostics
Helen Kourea, Vassiliki Kotoula
DNA damage, tumor mutational load and their impact on immune responses against cancer
Michalis Liontos, Ioannis Anastasiou, Aristotelis Bamias, Meletios-Athanasios Dimopoulos
The dual role of complement in cancer and its implication in anti-tumor therapy
Ioannis Kourtzelis, Stavros Rafail
Optimized tumor cryptic peptides: the basis for universal neo-antigen-like tumor vaccines
Jeanne Menez-Jamet, Catherine Gallou, Aude Rougeot, Kostas Kosmatopoulos
The European Organization for Research and Treatment of Cancer perspective on designing clinical trials with immune therapeutics
Jessica Menis, Saskia Litière, Konstantinos Tryfonidis, Vassilis Golfinopoulos
Immunotherapy in non-small cell lung cancer: the clinical impact of immune response and targeting
Giannis Mountzios, Helena Linardou, Paris Kosmidis
Melanoma immunotherapy dominates the field
Panagiotis Diamantopoulos, Helen Gogas
Immunobiology and immunotherapy in genitourinary malignancies
Marinos Tsiatas, Petros Grivas
The significance of tumor-associated immune response in molecular taxonomy, prognosis and therapy of colorectal cancer patients
Andreas Nearchou, George Pentheroudakis
Toxicity management of immunotherapy for patients with metastatic melanoma
Helena Linardou, Helen Gogas


Future perspectives in cancer immunotherapy
Marinos Tsiatas, Giannis Mountzios, Giuseppe Curigliano


The focused issue“Immunotherapy in cancer: the clinical impact of immune response and targeting”was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding. Vassiliki Kotoula and George Fountzilas served as the unpaid Guest Editors for the focused issue.