Lisa Huang, Ph.D.
MEDICAL DIAGNOSTIC LABORATORY L.L.C., Hamilton, NJ
Dr. Huang’s major research interests, at Medical Diagnostic Laboratories LLC (MDL), are to identify biomarkers and to develop non-invasive assays using biomarkers for cancer diagnostic, prognosis, and therapeutics. She mainly focuses on prostate cancer, cervical cancer, and bladder cancer. Their goal as research team is to understand tumor progression and response to chemotherapy, to identify cancer biomarkers and drug targets, and to translate our discoveries into clinical tests and small compound therapeutics that will contribute to the diagnosis and treatment of cancer. In conjunction with the Research and Development teams and the clinical laboratory of Medical Diagnostic Laboratories LLC, they are applying strategies to discover and evaluate potential cancer biomarkers for use in clinical testing. Currently, they are focused on biomarkers for early detection and evaluation of gynecologic and urologic cancers from sources such as cervical brushes, urine and blood. They are interested in dissecting the regulation of tumor development, metastasis, and drug resistance in the interest of understanding their molecular mechanisms, finding potential drug targets, and developing assays amenable for high-throughput screening of small compound and siRNA libraries.
Dr. Huang has broad and solid background in cancer biology, molecular biology, virology, and immunology, have multiple publications in these fields, and have expertise in biomarker discovery and clinical diagnostic assay development. She was trained as a molecular virologist in the Cancer Research Center at Purdue University, IN, where she earned her Ph.D. degree. She was a key scientist on a $7M NIH grant and successfully expanded her career in the field of cancer research during my postdoctoral training at Stanford University School of Medicine, CA, where she generated transgenic mice and studied in vitro and in vivo function of the human granulysin gene for cancer therapy. Furthermore, she have gained expertise in biomarker research during my training at Cornell Medical College in NYC, which was awarded a multi-center research grant ($3.7 M/year DARPA grant) focused upon the intricate processes involved in wound healing and tissue restoration.