Alexander Dobrovic, PhD
Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia
Associate Professor Alexander Dobrovic has a PhD and is an active researcher in cancer molecular genetics and pathology. He leads the Translational Genomics and Epigenomics Laboratory at the Olivia Newton-John Cancer Centre in Melbourne, Australia. The lab has a focus on personalized medicine including developing clinically relevant innovative diagnostic methodologies. This includes tests for detection of KRAS, BRAF and TP53 mutations that have entered routine diagnostics. A major research interest is in the emerging field examining the role of epigenetics in cancer predisposition, in particular the constitutional mosaic methylation of hereditary cancer and recessive cancer genes. This requires the development of methods of DNA methylation analysis that are both accurate and sensitive.