TY - JOUR AU - Berger, Joseph R. PY - 2019 TI - PD-1 inhibition: a novel approach to the treatment of progressive multifocal leukoencephalopathy JF - Annals of Translational Medicine; Vol 7, Supplement 8 (December 31, 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the brain due to an ubiquitous polyoma virus, JC virus, was first recognized in 1958 (1). PML was initially described in individuals with B cell malignancies, chronic lymphocytic leukemia and Hodgkins lymphoma, though it occurred with other predisposing illnesses as well. UR - https://atm.amegroups.org/article/view/32468