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ALPPS for hepatocarcinoma under cirrhosis: a feasible alternative to portal vein embolization

	author = {Victor Lopez-Lopez and Ricardo Robles-Campos and Roberto Brusadin and Asunción Lopez-Conesa and Jesus de la Peña and Albert Caballero and Julio Arevalo-Perez and Alvaro Navarro-Barrios and Paula Gómez and Pascual Parrilla-Paricio},
	title = {ALPPS for hepatocarcinoma under cirrhosis: a feasible alternative  to portal vein embolization},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {22},
	year = {2019},
	keywords = {},
	abstract = {Hepatocellular carcinoma (HCC) is one of the most common and malignant tumors. Preoperative portal vein embolization (PVE) is currently the most accepted treatment before major hepatic resection for HCC in patients with liver fibrosis or cirrhosis and associated insufficient future liver remnant (FLR). In the last decade, associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) technique has been described to obtain an increase of volume regarding PVE and a decrease of drop out. The initial excessive morbidity and mortality of this technique have decreased drastically due to a better selection of patients, the learning curve and the use of less aggressive variations of the original technique in the first stage. For both techniques a complete preoperative assessment of the FLR is the most important issue and only patients with and adequate FLR should be resected. ALPPS could be a feasible technique in very selected patients with HCC and cirrhosis. As long as it is performed in an experienced center could be used as a first choice technique versus PVE or could be used as a rescue technique in case of PVE failure.},
	issn = {2305-5847},	url = {}