TY - JOUR AU - Schild, Steven E. PY - 2019 TI - The PEMBRO-RT phase II randomized trial and the evolution of therapy for metastatic non-small cell lung cancer: a historical perspective JF - Annals of Translational Medicine; Vol 7, Supplement 8 (December 31, 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Lung cancer kills more individuals than any other malignancy. In the United States alone, it is estimated that 142,670 patients with die of this disease during 2019 (1). In 1995, Hellman and Weichselbaum proposed the existence of “ a clinically significant state of disease termed oligometastases that was in between purely localized and widely metastatic .” (2). This term was to be used to describe patients with “metastases to a single or a limited number of organs”. UR - https://atm.amegroups.org/article/view/31841