TY - JOUR AU - Dumas, Guillaume AU - Lemiale, Virginie AU - Demoule, Alexandre AU - Azoulay, Elie PY - 2019 TI - Improving survival in immunocompromised patients with hypoxemic acute respiratory failure JF - Annals of Translational Medicine; Vol 7, Supplement 8 (December 31, 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Over the last two decades, the number of patients living with immune deficiency has steadily increased (1). Even though a greater life expectancy could be achieved (2), immunocompromised patients still experience life- threatening complications warranting admission to the intensive care unit (ICU), chiefly for hypoxemic acute respiratory failure (ARF). Case fatality is high in ARF patients, especially when endotracheal intubation (ETI) is needed (3). Hence, oxygenation and ventilation strategies to avoid invasive mechanical ventilation have been widely evaluated in this setting. The single center trial from Hilbert et al. (4) which reported a significant reduction in intubation and mortality rates associated with noninvasive ventilation (NIV) has been challenged by larger and multicenter data (5,6). UR - https://atm.amegroups.org/article/view/31813