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Tumor deposit indicates worse prognosis than metastatic lymph node in gastric cancer: a propensity score matching study

  
@article{ATM31705,
	author = {Jianan Tan and Bin Yang and Zhimeng Xu and Shengning Zhou and Zhitao Chen and Jing Huang and Han Gao and Senyou Zheng and Liqiang Wen and Fanghai Han},
	title = {Tumor deposit indicates worse prognosis than metastatic lymph node in gastric cancer: a propensity score matching study},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {22},
	year = {2019},
	keywords = {},
	abstract = {Background: The prognostic value of tumor deposit (TD) in gastric cancer is controversial. This study aims to investigate the prognostic value of TD.
Methods: The consecutive patients diagnosed with gastric cancer from October 2007 to October 2012 were selected. The patients were divided by whether they suffered TD into two groups. The basic data were comparable between the two groups after propensity score matching (PSM), then survival analysis [overall survival (OS) and cancer-specific survival (CSS)] was applied in two groups. After that, all the patients were divided by pN staging and survival analysis were applied in each subgroup. At last, all patients were divided into TD group, pN1 stage group, pN2 stage group, pN3a, and pN3b stage group, OS and CSS were compared between them. Multivariable competing risk analyses tested association of TD with OS and CSS, before and after PSM.
Results: Eight hundred and three patients were concluded. After PSM, 137 patients with TD and 274 patients without TD were selected, the 5-year OS and CSS rates of patients with TD were significantly worse than patients without TD (OS: 19.7% vs. 42.0%, P},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/31705}
}