%0 Journal Article %T Serial bipolar androgen therapy (sBAT) using cyclic supraphysiologic testosterone (STP) to treat metastatic castration-resistant prostate cancer (mCRPC) %A Isaacs, John T. %A Brennen, W. Nathaniel %A Denmeade, Samuel R. %J Annals of Translational Medicine %D 2019 %B 2019 %9 %! Serial bipolar androgen therapy (sBAT) using cyclic supraphysiologic testosterone (STP) to treat metastatic castration-resistant prostate cancer (mCRPC) %K %X During prostate carcinogenesis, molecular changes occur in prostate epithelial cells such that their Androgen Receptor (AR) protein expression increases significantly (i.e. >5 fold). %U https://atm.amegroups.org/article/view/31303 %P S311 %@ 2305-5847