TY - JOUR AU - Xu, Fengrui AU - Wang, Xiaodi AU - Jiang, Zefei PY - 2019 TI - A right atrium metastasis of breast cancer after long-term endocrine therapy JF - Annals of Translational Medicine; Vol 7, No 22 (November 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - We report a case of right atrial metastasis in a 66-year-old female patient with breast cancer. The patient presented with palpitation and dyspnea after long-term endocrine therapy. A large echo-dense mass was found in the right atrium after the examination. In order to relieve the symptoms, the patient underwent a resection of the atrial lesion, and the pathology confirmed that it was metastatic breast cancer. Next-generation sequencing (NGS) of the entire exon was taken to explore the gene expression of the metastatic lesion. Forty-eighty genes were identified with mutations, and the mutations of ATM and ESR1 were considered to be associated with the development and metastasis of breast cancer in this case. UR - http://atm.amegroups.com/article/view/30057