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Cytoreductive nephrectomy following treatment with anti-vascular endothelial growth factor-targeted agents: is it surgically safe?

   
@article{ATM29775,
	author = {Hideaki Miyake},
	title = {Cytoreductive nephrectomy following treatment with anti-vascular endothelial growth factor-targeted agents: is it surgically safe?},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {Suppl 8},
	year = {2019},
	keywords = {},
	abstract = {In the era of cytokine therapy, 2 prospective randomized clinical trials (RCTs) demonstrated significantly more superior overall survival (OS) of metastatic renal cell carcinoma (mRCC) patients receiving cytoreductive nephrectomy followed by interferon-α (IFN-α) than of those treated with IFN-α alone (1,2); therefore, it has been recognized as a standard therapeutic approach for mRCC patients to perform cytoreductive nephrectomy prior to the introduction of systemic therapy.},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/29775}
}