TY - JOUR AU - Shaw, Jacqueline A. AU - Stebbing, Justin PY - 2013 TI - Circulating free DNA in the management of breast cancer JF - Annals of Translational Medicine; Vol 2, No 1 (January 25, 2014): Annals of Translational Medicine Y2 - 2013 KW - N2 - Circulating cell-free DNA (cfDNA) is now under investigation as a “liquid biopsy” in the real time management of cancer. In The New England Journal of Medicine Dawson et al. reported a proof of concept investigation of tumour specific alterations in cfDNA and demonstrate that this fraction termed “circulating tumour DNA” (ctDNA) shows greater correlation with changes in tumour burden than two other circulating biomarkers (CA 15-3 and circulating tumor cell counts) in individuals with metastatic breast cancer receiving therapy. UR - https://atm.amegroups.org/article/view/2930