%0 Journal Article %T Role of lipoprotein (a) in peripheral arterial disease %A Kosmas, Constantine E. %A Silverio, Delia %A Sourlas, Andreas %A Peralta, Richard %A Montan, Peter D. %A Guzman, Eliscer %A Garcia, Mario J. %J Annals of Translational Medicine %D 2019 %B 2019 %9 %! Role of lipoprotein (a) in peripheral arterial disease %K %X Lipoprotein (a) [Lp(a)] is a complex polymorphic lipoprotein synthesized by the liver, which is structurally similar to low-density lipoprotein (LDL). Like the LDL molecule, Lp(a) is composed of apolipoprotein B-100 (ApoB-100) but differs in that its ApoB-100 molecule is attached to apolipoprotein (a) [apo(a)], a polymorphic glycoprotein not found in the LDL molecule (1). Plasma levels of Lp(a) are primarily genetically determined by the LPA gene locus, independently of dietary or environmental factors (2). %U https://atm.amegroups.org/article/view/28740 %P S242 %@ 2305-5847