TY - JOUR AU - Ramchand, Jay AU - Desai, Milind Y. PY - 2019 TI - Clinical dilemmas in predicting the progression of pre-clinical hypertrophic cardiomyopathy—is MRI strain the solution? JF - Annals of Translational Medicine; Vol 7, Supplement 6 (September 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Hypertrophic cardiomyopathy (HCM) is one of the commonest inherited cardiac diseases, with an estimated prevalence of 1 in 500 (1). It is characterized by unexplained myocardial hypertrophy, which occurs in the absence of pressure overload (e.g., hypertension, aortic stenosis) or infiltration (e.g. amyloidosis) (2,3). Myocardial hypertrophy in HCM typically occurs in the interventricular septum but can also be apical, segmental, or concentric. HCM is primarily a genetic disease involving mutations in at least 14 genes (2,4). UR - http://atm.amegroups.com/article/view/28282