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Predictive role of intraoperative clinicopathological features of the central compartment in estimating lymph nodes metastasis status

  
@article{ATM28118,
	author = {Rong-Hao Sun and Chao Li and Yu-Qiu Zhou and Yong-Cong Cai and Chun-Yan Shui and Wei Liu and Xu Wang and Din-Fen Zeng and Jian Jiang and Jing-Qiang Zhu},
	title = {Predictive role of intraoperative clinicopathological features of the central compartment in estimating lymph nodes metastasis status},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {18},
	year = {2019},
	keywords = {},
	abstract = {Background: To explore the feasibility of immediate assessment, which focuses on clinicopathological characteristics of central lymph nodes (LNs) during operation. Moreover, to analyze the predictive effect of various evaluated indicators on the nature, quantities, and ratios of central lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC), to provide the basis for precise individualized central lymph node dissection (LND). 
Methods: According to the inclusion and exclusion criteria, 1,271 PTC patients were selected in this cohort study. In the study, the clinical and pathological characteristics of the central LNs were evaluated by the treatment groups during the operation, which had a similar therapeutic experience. The parameters including the texture, volume, maximum/vertical meridian, extracapsular infiltration, adhesion or fusion, and nano-carbon staining status of the central LNs were collected. According to the pathological results after the operation, the nature, quantities, and rate of LNM in the central compartment were counted. The relationship between these parameters and metastatic nature, quantities, and ratios was analyzed and compared. 
Results: Univariate analysis showed that when the larger size of LNs (especially the maximum meridian >0.9 cm), extracapsular infiltration, adhesion and fusion being found, A higher possibility of LNM in the central compartment (P},
	issn = {2305-5847},	url = {http://atm.amegroups.com/article/view/28118}
}