TY - JOUR AU - González, Javier AU - Ciancio, Gaetano PY - 2019 TI - Renal cell carcinoma response to checkpoint inhibitors may be predicted by senescence activity in tumor microenvironment JF - Annals of Translational Medicine; Vol 7, Supplement 3 (July 30, 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Renal cell carcinoma (RCC) represents a tailor’s box composed of different forms of disease, each of them characterized by a complex relationship scenario established between the different actors involved (i.e., tumor cells, immune cells, and their respective expression products or tumoral microenvironment). This panorama favors a wide variety of biological behaviors (covering the spectrum between the slow-indolent to aggressive-invasive growth patterns) that are difficult to predict exclusively from a clinical standpoint (1). UR - https://atm.amegroups.org/article/view/26445