TY - JOUR AU - Wu, Kai-Ze AU - Huang, Ze-Han AU - Zhong, Zhi-An AU - Liao, Hong-Tao AU - Zhou, Yi AU - Luo, Bing-Zheng AU - Anantha-Narayanan, Mahesh AU - Khouzam, Rami N. AU - Garg, Aakash AU - Vukcevic, Vladan AU - Kounis, Nicholas G. AU - Zhang, Bin AU - AME Cardiovascular Disease Collaborative Group, written on behalf of the PY - 2019 TI - Successful treatment of complex coronary chronic total occlusions improves midterm outcomes JF - Annals of Translational Medicine; Vol 7, No 9 (May 15, 2019): Annals of Translational Medicine Y2 - 2019 KW - N2 - Background: Data regarding outcomes of percutaneous coronary intervention (PCI) in patients with chronic total occlusion (CTO) is still limited. Our aim was to evaluate clinical outcomes in patients after successful CTO PCI when compared to patients with failed PCI. Methods: The cohort study enrolled 145 eligible patients with attempted PCI of CTO. Detailed baseline clinical and procedural data, and in-hospital complications were analyzed. The primary end point was occurrence of major adverse cardiac events (MACE). Results: Median follow-up was 11.49±2.01 months. Successful revascularization was associated with a significantly lower 1-year MACE compared to failed revascularization [hazard ratio (HR): 0.026; 95% confidence interval (CI): 0.004–0.176; P=0.0002]. A J-CTO score of ≥3 was associated with a significantly higher 1-year MACE compared with a J-CTO score of Conclusions: Among patients with CTOs, high J-CTO score was independently associated with worse clinical outcomes. Furthermore, successful PCI was associated with a lower risk of midterm MACE compared with failed revascularization of CTOs. UR - https://atm.amegroups.org/article/view/25635