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Prevalent osteoporotic vertebral fractures more likely involve the upper endplate than the lower endplate and even more so in males

  
@article{ATM22209,
	author = {Nazmi Che-Nordin and Min Deng and James F. Griffith and Jason C. S. Leung and Anthony W. L. Kwok and Yue-Qi Zhu and Richard H. Y. So and Timothy C. Y. Kwok and Ping Chung Leung and Yì Xiáng J. Wáng},
	title = {Prevalent osteoporotic vertebral fractures more likely involve the upper endplate than the lower endplate and even more so in males},
	journal = {Annals of Translational Medicine},
	volume = {6},
	number = {22},
	year = {2018},
	keywords = {},
	abstract = {Background: While the importance of identifying osteoporotic vertebral endplate fracture (EPF) is being recognized; the pathophysiological understanding of EPF till now remain insufficient. In this population-based cross-sectional radiograph study, we aim to investigate the anatomic location characteristics of osteoporotic EPF.
Methods: This study analyzed the anatomical location of osteoporotic EPFs in elderly Chinese population (age ≥65 years). The T4–L4 radiographs of 1,954 elderly Chinese men (mean: 72.3 years) and 1,953 elderly Chinese women (mean: 72.5 years) were evaluated to identify EPF, and vertebral bodies were graded according to Genant’s vertebral deformity criteria. 
Results: Of the 101,582 endplates analyzed, there were 505 EPFs (males: 27.7%; females: 72.3%). Excluding those with both upper endplate and lower endplate involvements, the ratio of upper EPF to lower EPF was 9.63 for males and 4.3 for females (P},
	issn = {2305-5847},	url = {http://atm.amegroups.com/article/view/22209}
}