%0 Journal Article %T Simulation modeling for clinical trials evaluating radiotherapy omission in low-risk early breast cancer %A Franco, Pierfrancesco %A Ricardi, Umberto %J Annals of Translational Medicine %D 2018 %B 2018 %9 %! Simulation modeling for clinical trials evaluating radiotherapy omission in low-risk early breast cancer %K %X Adjuvant whole breast radiation therapy (WBI) is regarded as a standard approach for early-stage breast cancer (EBC) patients after breast conservation surgery (BCS) (1,2). It is able to halve the 10–year rate of any breast cancer recurrence (absolute reduction: 15.7%) and to reduce by about 1/6 th the 15-year breast cancer-related mortality (absolute reduction: 3.8%) (3). %U https://atm.amegroups.org/article/view/21701 %P S43 %@ 2305-5847