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Surrogate study endpoints in the era of cancer immunotherapy

   
@article{ATM21385,
	author = {Tsuyoshi Hamada and Keisuke Kosumi and Yousuke Nakai and Kazuhiko Koike},
	title = {Surrogate study endpoints in the era of cancer immunotherapy},
	journal = {Annals of Translational Medicine},
	volume = {6},
	number = {Suppl 1},
	year = {2018},
	keywords = {},
	abstract = {The choice of a primary endpoint is a matter of ongoing debate in the design of clinical oncology trials testing new treatment regimens. Overall survival (OS) time of patients serves as a gold-standard endpoint in phase III clinical trials testing first-line chemotherapy for cancers, because this outcome variable ultimately represents survival benefits from chemotherapy regimens and has minimal measurement errors.},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/21385}
}