TY - JOUR AU - Çelik, Mevlüt AU - Durko, Andras P. AU - Head, Stuart J. PY - 2018 TI - Anticoagulation after mechanical aortic valve implantation: is it time to act after PROACT? JF - Annals of Translational Medicine; Vol 6, Supplement 1 (November 29, 2018): Annals of Translational Medicine Y2 - 2018 KW - N2 - Anticoagulation management after mechanical prosthetic heart valve (PHV) implantation should find the delicate balance between effectively preventing valve-related thromboembolic events while not substantially increasing the risk of bleeding (1). Mechanical PHVs traditionally require lifelong anticoagulation with vitamin K antagonists (VKAs). UR - https://atm.amegroups.org/article/view/21247