TY - JOUR AU - Bernhagen, Jürgen PY - 2018 TI - “Remote” myokine protects from pulmonary ischemia/reperfusion injury by a surprising “proximal” control mechanism JF - Annals of Translational Medicine; Vol 6, No 13 (July 13, 2018): Annals of Translational Medicine (Focus on “Quality in Gastrointestinal Endoscopy”) Y2 - 2018 KW - N2 - The concept of remote ischemic preconditioning (RIPC) was first conceived more than quarter of a century ago in the context of myocardial ischemia/reperfusion (I/R) injury. It was originally based on the principle of “intra”-myocardial protection, i.e., to reduce myocardial I/R damage by subjecting the heart to cycles of “sub-lethal” myocardial I/R prior to prolonged coronary artery occlusion, which however was clinically restricted to elective cardiac surgery settings (1). UR - https://atm.amegroups.org/article/view/19790