TY - JOUR AU - Venkata Pothineni, Naga AU - Shah, Nishi N. AU - Rochlani, Yogita AU - Saad, Marwan AU - Kovelamudi, Swathi AU - Marmagkiolis, Konstantinos AU - Bhatti, Sabha AU - Cilingiroglu, Mehmet AU - Aronow, Wilbert S. AU - Hakeem, Abdul PY - 2017 TI - Temporal trends and outcomes of acute myocardial infarction in patients with cancer JF - Annals of Translational Medicine; Vol 5, No 24 (December 14, 2017): Annals of Translational Medicine Y2 - 2017 KW - N2 - Background: Data on outcomes of ST-elevation myocardial infarction (STEMI) in patients with cancer are scarce. We investigated the nationwide trends in admissions for STEMI, utilization of percutaneous coronary intervention (PCI), and in-hospital outcomes in patients with the three most common cancer diagnoses (lung, breast, and colon) compared to patients without cancer. Methods: We conducted an administrative database study using the Nationwide Inpatient Sample (NIS). All in-patient hospitalizations for STEMI from 2001 to 2011 were identified. Patients with concomitant diagnosis of lung, breast or colon cancer were identified using appropriate International classification of diagnosis (ICD 9-CM) codes. Primary outcome was utilization of PCI and in-hospital mortality in patients with cancer compared to those without cancer. Results: Utilization of PCI was 30.8% (1,191/3,871), 20.2% (4,541/22,480) and 17.3% (1,716/9,944) in patients with breast, lung and colon cancer, respectively. Among patients without any of these cancers, use of PCI was 49.6%. In-hospital mortality was highest in patients with lung cancer (57.1%) and lowest in patients without cancer (25.7%). Conclusions: Patients with cancer have significantly worse in-hospital mortality compared to those without cancer, partly due to a relatively lower rate of PCI utilization in cancer patients with STEMI. UR - https://atm.amegroups.org/article/view/17707