TY - JOUR AU - Budini, Mauricio AU - Criollo, Alfredo PY - 2017 TI - Poly(GP) proteins: a potential pharmacodynamic marker in ALS and FTD JF - Annals of Translational Medicine; Vol 5, No 24 (December 14, 2017): Annals of Translational Medicine Y2 - 2017 KW - N2 - Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. The genetic factor chromosome 9 open reading frame 72, C9ORF72 , has been closely associated not only with the development of ALS, but also with frontotemporal dementia (FTD) characterized by a progressive cognitive decline, altered personality and impairment in language (1,2). UR - https://atm.amegroups.org/article/view/17665