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Micro-RNAs as promising biomarkers in cardiac diseases

  
@article{ATM13011,
	author = {Mariama Akodad and Mathias Mericskay and Fran├žois Roubille},
	title = {Micro-RNAs as promising biomarkers in cardiac diseases},
	journal = {Annals of Translational Medicine},
	volume = {4},
	number = {24},
	year = {2016},
	keywords = {},
	abstract = {miRNAs are endogenous, small (21-22 nucleotides), single-stranded, non-coding RNAs recently discovered (1). miRNAs complexed with Ago proteins (RISC complex) regulate gene expression by binding to reverse complementary sequences in their target mRNAs leading to mRNA degradation and/or repression of protein translation (2). Circulating miRNAs can be detected in serum or plasma and have been proposed as potential biomarkers for cardiovascular diseases, with high sensitivity (3).},
	issn = {2305-5847},	url = {http://atm.amegroups.com/article/view/13011}
}