TY - JOUR AU - Perales, María AU - Santos-Lozano, Alejandro AU - Sanchis-Gomar, Fabian AU - Luaces, María AU - Pareja-Galeano, Helios AU - Garatachea, Nuria AU - Barakat, Rubén AU - Lucia, Alejandro PY - 2016 TI - Impact of gestational risk factors on maternal cardiovascular system JF - Annals of Translational Medicine; Vol 4, No 13 (July 15, 2016): Annals of Translational Medicine (Focus on “State of the art in diagnostics of the Acute Coronary Syndrome”) Y2 - 2016 KW - N2 - Background: Scarce evidence is available on the potential cardiovascular abnormalities associated with some common gestational complications. We aimed to analyze the potential maternal cardiac alterations related to gestational complications, including body mass index (BMI) >25 kg/m 2 , gaining excessive weight, or developing antenatal depression. Methods: The design of this study was a secondary analysis of a randomized controlled trial. Echocardiography was performed to assess cardiovascular indicators of maternal hemodynamic, cardiac remodeling and left ventricular (LV) function in 59 sedentary pregnant women at 20 and 34 weeks of gestation. Results: Starting pregnancy with a BMI >25 kg/m 2 , gaining excessive weight, and developing antenatal depression had no cardiovascular impact on maternal health (P value >0.002). Depressed women were more likely to exceed weight gain recommendations than non-depressed women (P value Conclusions: The evaluated gestational complications seem not to induce cardiovascular alterations in hemodynamic, remodeling and LV function indicators. However, developing antenatal depression increases the risk of an excessive weight gain. This finding is potentially important because excessive weight gain during pregnancy associates with a higher risk of cardiovascular diseases (CVD) later in life. UR - https://atm.amegroups.org/article/view/10870