Focus on “State of the art in diagnostics of the Acute Coronary Syndrome” Guest Edited by Prof. Giuseppe Lippi and Prof. Gianfranco Cervellin

Posted On 2016-07-20 09:58:18

Welcome to this special issue of Annals of Translational Medicine (ATM). The acute coronary syndrome (ACS) is now recognized as the leading cause of death and disability worldwide. Incidentally, acute cardiac ischemia has been considered for decades as the culprit of a lifelong atherosclerotic chronic disease (1), which may persists undetected for long, but that can ultimately emerge in the form of an acute myocardial infarction (AMI), causing catastrophic consequences on heart structure and function, up to sudden death and/or severe and permanent hemodynamic deterioration (2). The clinical approach to patients with an ACS has engaged the minds of many scientists, but still many questions about the pathophysiology, diagnostics and therapeutic management of this condition remain unanswered (3). It is exactly for these reasons that this special issue of the journal has been though and scheduled.

Focus on State of the Art in Diagnostics of the Acute Coronary Syndrome

Acute coronary syndrome: many doubts, some answers
Giuseppe Lippi, Gianfranco Cervellin
High-density lipoprotein cholesterol values independently and inversely predict cardiac troponin T and I concentration
Giuseppe Lippi, Claudia Lo Cascio, Giorgio Brocco, Elisa Danese, Martina Montagnana, Antonella Bassi, Beatrice Caruso, Chiara Bovo, Gian Luca Salvagno
The relationship between ABO blood group and cardiovascular disease: results from the Cardiorisk program
Enrico Capuzzo, Carlo Bonfanti, Francesco Frattini, Paolo Montorsi, Rosalia Turdo, Maria Grazia Previdi, Elisa Turrini, Massimo Franchini
Lower mean corpuscular hemoglobin concentration is associated with poorer outcomes in intensive care unit admitted patients with acute myocardial infarction
Yuan-Lan Huang, Zhi-De Hu
The clinics of acute coronary syndrome
Gianfranco Cervellin, Gianni Rastelli
Genetics of the acute coronary syndrome
Massimo Franchini
Diagnostic algorithms for acute coronary syndrome—is one better than another?
Gianfranco Cervellin, Camilla Mattiuzzi, Chiara Bovo, Giuseppe Lippi
An historical approach to the diagnostic biomarkers of acute coronary syndrome
Elisa Danese, Martina Montagnana
Evidence and pitfalls in diagnosis and prognostication of acute coronary syndrome
Giuseppe Lippi, Gianfranco Cervellin

High-sensitivity cardiac troponin testing for primary care: analytical assay considerations required before widespread implementation
Alan H. B. Wu

Predictive significance of detectable cardiac troponin I measured with a contemporary-sensitive assay in a real life experience
Laura Bonfanti, Giuseppe Lippi, Irene Ciullo, Tiziana Meschi, Andrea Ticinesi, Rosalia Aloe, Francesco Di Spigno, Gianfranco Cervellin

Impact of gestational risk factors on maternal cardiovascular system
María Perales, Alejandro Santos-Lozano, Fabian Sanchis-Gomar, María Luaces, Helios Pareja-Galeano, Nuria Garatachea, Rubén Barakat, Alejandro Lucia

Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome
Gianni Turcato, Valentina Serafini, Alice Dilda, Chiara Bovo, Beatrice Caruso, Giorgio Ricci, Giuseppe Lippi

Coronary computed tomography angiography (CCTA) and cardiac magnetic resonance (CMR) imaging in the assessment of patients presenting with chest pain suspected for acute coronary syndrome
Massimo De Filippo, Raffaella Capasso

Epidemiology of coronary heart disease and acute coronary syndrome
Fabian Sanchis-Gomar, Carme Perez-Quilis, Roman Leischik, Alejandro Lucia

High-sensitivity cardiac troponin testing in routine practice: economic and organizational advantages
Claudio Galli, Giuseppe Lippi

Prognostic biomarkers in acute coronary syndrome
Gian Luca Salvagno, Chiara Pavan

Echocardiographic assessment of myocardial ischemia
Roman Leischik, Birgit Dworrak, Fabian Sanchis-Gomar, Alejandro Lucia, Thomas Buck, Raimund Erbel

Guest Editors: Prof. Giuseppe Lippi and Prof. Gianfranco Cervellin