Vol 7, Supplement 1 (March 2019): Annals of Translational Medicine

Editorial Commentary

Patient centered care for prostate cancer—how can artificial intelligence and machine learning help make the right decision for the right patient?
Nathan C. Wong, Bobby Shayegan
Meningeal lymphatics in aging and Alzheimer’s disease
Russell J. Jaffe, Rajnish S. Dave, Siddappa N. Byrareddy
Pembrolizumab in advanced gastric cancer: pioneering or prosaic?
Sarbajit Mukherjee, Steven N. Hochwald
Improving detection combined with targeted therapy for small hepatocellular carcinoma
Shengyang Qiu, Long R. Jiao
Is the onset of adverse effects of immunotherapy always bad news for the patients…?—certainly not!
Paul Hofman
Fluorescence-guided surgery in cancer treatment: current status and future perspectives
Yongchang Zheng, Huayu Yang, Henan Wang, Kai Kang, Wenkai Zhang, Gang Ma, Shunda Du
Blocking the PD-1/PD-L1 axis in advanced prostate cancer: are we moving in the right direction?
Andre P. Fay, Emmanuel S. Antonarakis
Pathophysiology of pain in patients with peritoneal endometriosis
Simone Ferrero, Valerio Gaetano Vellone, Fabio Barra
Lessons learned by features of pancreatic ductal adenocarcinoma and its tumor microenvironment
Alex B. Blair, Vincent P. Groot, Jin He
American Joint Committee on Cancer 8th edition staging—an improvement in prognostication in HPV-associated oropharyngeal cancer?
Jon Mallen-St Clair, Allen S. Ho
Eighth edition of the American Joint Committee on Cancer staging system for soft tissue sarcoma of the trunk and extremity: in search of a better staging system
Kazuhiro Tanaka, Hiroshi Tsumura
Cancer staging for rare cancers: should the American Joint Committee on Cancer have a separate staging classification for external auditory canal cancer?
Jonathan Robert Clark, Hubert Low, Ruta Gupta
Mitochondrial cytochrome c oxidase is not the primary acceptor for near infrared light—it is mitochondrial bound water: the principles of low-level light therapy
Andrei P. Sommer
Pembrolizumab for recurrent/metastatic head and neck cancer: equally promising for Asian patients?
Wenda Ye, Nicole C. Schmitt
Single nucleotide polymorphisms in angiogenesis-related genes and outcomes from antiangiogenic therapies in renal cell carcinoma: really a step towards personalized oncology, or not at all?
Camillo Porta, Laura Cosmai, Mimma Rizzo, Mario Melazzini
Ultrasound patterns of pulmonary edema
Gino Soldati, Marcello Demi, Libertario Demi
There is another new method for cryopreserving small numbers of human sperm cells
Alessio Paffoni, Simone Palini
Revisiting AJCC TNM staging for renal cell carcinoma: quest for improvement
Umang Swami, Roberto H. Nussenzveig, Benjamin Haaland, Neeraj Agarwal
Monocyte-platelet cross-talk in peripheral artery disease—how much does the pathogenesis of atherosclerosis depend on anatomical location?
Richard A. Brown, Gregory Y. H. Lip
The variables of force generation and application to cartilage, ligaments and bone remain to be defined
Robert A. Teitge
Orphan noncoding RNAs: novel regulators and cancer biomarkers
Mona Teng, Lydia Y. Liu, Junjie Tony Hua, Sujun Chen, Housheng Hansen He
Immunotherapeutic strategies in patients with advanced head and neck squamous cell carcinoma
Maysaloun Merhi, Afsheen Raza, Varghese Inchakalody, Abdul Rahman Zar, Shahab Uddin, Said Dermime
Important caveats of KEYNOTE-045: relevance of these findings in the current and future therapeutic paradigm
Julio Slongo, Rohit K. Jain, Philippe E. Spiess
The use of baseline tumor size to prognosticate overall survival in stage IV melanoma patients treated with the PD-1 inhibitor pembrolizumab
Philip Friedlander
Norepinephrine, more than a vasopressor
Emilio Daniel Valenzuela Espinoza, Glenn Hernandez, Jan Bakker
A nomogram for predicting survival of patients with locally advanced pancreatic cancer treated with chemoradiotherapy: an editorial comment
Joyce Wong
Electronic health records, physician workflows and system change: defining a pathway to better healthcare
Carla M. Pugh
Nephron repair: powered by anaerobic energy metabolism
Brooke E. Chambers, Rebecca A. Wingert
Nanoparticles as theranostic vehicles in prostate cancer
Rafael Morales-Barrera, Cristina Suárez, Joaquín Mateo, Macarena González, Joan Carles
Mind the gap: renal tubule responses to injury and the role of Cxcl12 and Myc
Veronika Sander, Richard W. Naylor, Alan J. Davidson
Anterior knee pain as a functional problem of complex dynamic inter-play of living structures
Werner Müller
Is an immune checkpoint inhibitor really a hopeless therapeutic choice for EGFR-mutant non-small cell lung cancer (NSCLC) patients?
Kei Kunimasa, Kazumi Nishino, Toru Kumagai
Strengthening the foundation of kidney cancer treatment and research: revising the AJCC staging system
Hiren V. Patel, Arnav Srivastava, Brian Shinder, Evita Sadimin, Eric A. Singer
Anatomy is not enough: the crucial role of biology and genetics in AJCC eighth edition of the TNM classification for breast cancer
Francesca Magnoni, Giuseppe Accardo, Elisabetta Rossi, Paolo Veronesi, Giovanni Corso
When survival curves cross: are we at a crossroads of immunotherapy in gastric cancer?
Jun Gong, Joseph Chao
Editorial on “Risk prediction models for cancer-specific survival following cytoreductive nephrectomy in the contemporary era”
Yasmin Abu-Ghanem, Jacob Ramon
The potential role of germline single nucleotide polymorphisms for selecting the ideal candidates for sunitinib therapy in patients with locally-advanced renal cell carcinoma
Alberto Martini, Reza Mehrazin
Adjuvant therapy in renal cell carcinoma—is pharmacogenomics assessment another element to select our patients?
Vincenzo Di Nunno, Veronica Mollica, Lidia Gatto, Matteo Santoni, Giulia Sorgentoni, Nicola Battelli, Francesco Massari
Optimizing renal function and outcome of patients with cT2 renal cell carcinoma
Matteo Santoni, Giada Maiorani, Luca Faloppi, Vincenzo Di Nunno, Lidia Gatto, Francesco Massari, Nicola Battelli
Stem cell therapy in diabetic men with erectile dysfunction: a step closer to safe and effective regenerative technology
Eric Chung
UICC and AJCC 8th edition tumor-nodes-metastasis (TNM) classifications for patients treated with radical prostatectomy: reliable but not infallible prognostic tools
Marco Bandini, Felix Preisser
Chronic obstructive pulmonary disease alters immune cell composition and immune checkpoint inhibitor efficacy in non-small cell lung cancer
Marcos Magalhães Filho, Pedro N. Aguiar Jr, Ramon Andrade de Mello
Fine-tuning autophagy in pancreatic adenocarcinoma: full blockage is required
Nicolas Jonckheere, Isabelle Van Seuningen
Is smoking causally-associated with hepatitis B virus-related hepatocellular carcinoma?
Kyrillus S. Shohdy, Omar Abdel-Rahman
Predicting renal function after kidney cancer surgery: a tool for clinical decision making
Natalie R. Swavley, Alessandro Veccia, Riccardo Autorino
Potential biological and clinical benefit of prostate-directed interventions in patients with metastatic prostate cancer
Makito Miyake, Takuya Owari, Nobumich Tanaka, Kiyohide Fujimoto
What is the most durable construct for a forefoot amputation, traditional transmetatarsal amputation or a medial ray sparing procedure?
Lawrence A. Lavery, Peter A. Crisologo, Metin Yavuz
Systemic therapy of elderly patients with advanced non-small cell lung cancer—individualized treatment is key
Robert Pirker
Thyroid cancer staging and genomics
Ashok R. Shaha, R. Michael Tuttle
Encouraging early outcomes in cancer and leukemia group B (CALGB)/Alliance 140503: patient selection, not extent of resection, is the key to perioperative success
Kyle G. Mitchell, Mara B. Antonoff
Implementation of staging systems in clinical practice for cutaneous squamous cell carcinoma
Javier Cañueto
Eighth edition of the American Joint Committee on Cancer staging system: are we getting closer to the ideal classification for gastric cancer?
Karen Elizabeth Padilla-Leal, Heriberto Medina-Franco
An extended overall survival analysis of pemetrexed and carboplatin with or without pembrolizumab as first-line therapy for advanced non-squamous non-small cell lung cancer
Muhammad Zubair Afzal, Konstantin H. Dragnev, Keisuke Shirai
Pathological nodal staging score for renal cell carcinoma: how to build reliable therapeutic choices basing on assumptions
Melissa Bersanelli, Sebastiano Buti, Matteo Santoni, Francesco Ziglioli, Umberto Maestroni