Vol 6, Supplement 1 (November 2018): Annals of Translational Medicine

Editorial

The new basal insulin analog glargine U-300 enables flexible injection schedule
Uru Nezu Osada, Yasuo Terauchi
Molecular imaging in large vessel vasculitis has come to stay
Isabel Martínez-Rodríguez, Miguel A. González-Gay, Diana Prieto-Peña, Ignacio Banzo
Local modalities for inoperable hepatocellular carcinoma: radiofrequency ablation versus stereotactic body radiotherapy
Sun Hyun Bae, Hee Chul Park
Calcium and/or vitamin D supplementation: could they affect your risks of colorectal cancer development or progression?
Lynnette R. Ferguson
Search for a reliable biomarker of acute kidney injury: to the heart of the problem
Luca Di Lullo, Biagio Raffaele Di Iorio, Claudio Ronco, Antonio Bellasi
Tumor inactivation of E-cadherin: a new tool for breast cancer treatment?
Giovanni Corso, Bernardo Bonanni, Paolo Veronesi
HLA-B*58:01 is not the only risk factor associated with allopurinol-induced severe cutaneous adverse drug reactions
Margarida Gonçalo
TBX20 and the PROK2-PROKR1 pathway—new kid on the block in angiogenesis research
Michael Lichtenauer, Christian Jung
Is B-type natriuretic peptide (BNP) similarly associated with mortality in patients with and without heart failure?
Norihide Fukushima
Durability of mitral valve repair for degenerative mitral regurgitation: is it gold all that glitters?
Antonio M. Calafiore, Antonio Totaro, Massimiliano Foschi, Michele Di Mauro
The benefits of youth sports participation should outweigh the risks
Carola F. van Eck, Freddie H. Fu
Ifi204/p204, a new piece in the sepsis puzzle
Gayatri Subramanian, Ritu Chakravarti, Saurabh Chattopadhyay
Validating innovations to improve recovery after heart surgery
Ali Fatehi Hassanabad, Paul W. M. Fedak
Genetics in systemic lupus erythematosus: entering the borough of cardiovascular risk
Giuseppe A. Ramirez
Self-condensation culture for vascularized organoid
Shoichiro Sumi
Anticoagulation after mechanical aortic valve implantation: is it time to act after PROACT?
Mevlüt Çelik, Andras P. Durko, Stuart J. Head
Cardiac troponin I—more than a biomarker for myocardial ischemia?
Li Ni, Xander H. T. Wehrens
The status of medical expulsive therapy in the age of evidence-based medicine
Julian Veser, Christian Seitz
Osteochondral lesions of the talus: are we ready for metal?
Riccardo D’Ambrosi, Federico Giuseppe Usuelli
Extracorporeal membrane oxygenation in acute respiratory distress syndrome: why is the EOLIA trial important?
Nicolas Persico, Christophe Guervilly, Antoine Roch, Laurent Papazian
Fusion heals the broken-hearted
Daniel A. Zuppo, Michael Tsang
Evaluation of kinematic changes of intervertebral discs and the space available for the cord
Federico Canavese, Yann Philippe Charles, Alain Dimeglio
Immunoscore—has it scored for colon cancer precision medicine?
Robert N. Jorissen, Anuratha Sakthianandeswaren, Oliver M. Sieber
High-density lipoprotein lifts the “dark web” cast by neutrophils
Diego Lucero, Edward B. Neufeld, Alan T. Remaley
The hemodynamic effects of norepinephrine: far more than an increase in blood pressure!
Pierre Foulon, Daniel De Backer
Screening of three-dimensional spheroids of ovarian cancer: identification of novel therapeutics targeting stemness and chemoresistance
Neveen Said
Surrogate study endpoints in the era of cancer immunotherapy
Tsuyoshi Hamada, Keisuke Kosumi, Yousuke Nakai, Kazuhiko Koike
LXRs are finally being adequately targeted in atherosclerosis
Julio Buñay, Silvère Baron, Jean-Marc A. Lobaccaro
EBOV-RNA test with RT-PCR in ocular fluids of Ebola survivors can help to safely perform cataract surgery
Leopoldo Spadea, Nicola Iozzo
Reforming disease classification system—are we there yet?
Mikhail G. Dozmorov
Treatment of induction in resectable NSCLC with chemotherapy, followed by surgery and erlotinib
Fernando Franco, Mariano Provencio
The answer is cilia, whatever the question may be!
Andrew Bush, Claire Hogg
Standardising measures in pediatric rheumatology: the experience of the international consensus dataset for juvenile dermatomyositis
Giovanni Filocamo
Treating atherosclerosis: targeting risk factors should not be the only option
Montserrat Fibla, Anna Hernández-Aguilera, Jordi Camps, Javier A. Menendez, Jorge Joven
Silent myocardial infarction and risk of heart failure
Timir K. Paul, Debabrata Mukherjee
We should not avoid diclofenac in the treatment of spondyloarthritis
Gerhard Zingler, Thomas Herdegen
Endoscopic saphenous vein harvesting and surgical site infections after coronary artery bypass surgery
Antonio Salsano, Giovanni Mariscalco, Francesco Santini
Host-pathogen interactions in typhoid fever: the model is the message
Verónica Urdaneta, Josep Casadesús
Ebola virus and persistent chronic infection: when does replication cease?
John V. Forrester
Pacific Rim redux: lorlatinib, the ultimate Jaeger?
Viola W. Zhu, Sai-Hong Ignatius Ou
Re-biopsy in lupus nephritis
Hans-Joachim Anders
Neuropathic pain models and outcome measures: a dual translational challenge
Robert D. E. Sewell
Simulation modeling for clinical trials evaluating radiotherapy omission in low-risk early breast cancer
Pierfrancesco Franco, Umberto Ricardi
Discovering the genetic contribution to cardiovascular diseases in patients affected by autoimmune diseases
Cinzia Ciccacci
The fecal microbiome directly drives immune activation in HIV infection
Camilla Tincati, Giuseppe Ancona, Giulia Marchetti
Risk of peripheral artery disease in human immunodeficiency virus infected individuals
Kevin Belgrave, Kashif Shaikh, Matthew J. Budoff
The different path of T790M-positive EGFR-mutant lung cancer
Shinkyo Yoon, Chang Min Choi, Jae Cheol Lee
Non-invasive assessment of tumor PD-L1 status with circulating tumor cells
Bryan C. Ulrich, Nicolas Guibert
Targeting selected extracellular matrix components to attenuate cardiac fibrosis
Simranjit S. Pattar, Ali Fatehi Hassanabad, Paul W. M. Fedak
Cardiovascular risk prediction in older adults with the use of biomarkers
Alexandros Briasoulis, Rabea Asleh
Radiologic features of small pulmonary nodules detected in initially negative screening CT examinations: a step towards personalized screening strategies?
Gorka Bastarrika, Juan Pablo de-Torres, Javier J. Zulueta
Progressive nature of myocardial fibrosis in pediatric hypertrophic cardiomyopathy: from mutation carrier to myocardial fibrosis
Hong-Mi Choi, Hyung-Kwan Kim
Epithelial plasticity is crucial for pancreatic cancer metastatic organotropism
Aleksandra Adamska, Marco Falasca
Issues in implementing lung cancer screening in United States and Europe
Giuseppe Gorini, Giulia Carreras
Cholesterol homeostasis, macrophage malfunction and age-related macular degeneration
Mei Chen, Chi-Chao Chan, Heping Xu
New highlight in breast cancer development: the key role of hepcidin and iron metabolism
Manuel Scimeca, Elena Bonanno
MK-2206 window of opportunity study in breast cancer
Argun Akcakanat, Funda Meric-Bernstam
Cerebrovascular contribution to dementia development after traumatic brain injury: promises and problems
Lyndsey Collins-Praino, Frances Corrigan
Office-based spirometry to stratify the risk of postoperative complications
Shigeki Suzuki, Yusuke Takahashi
Dasatinib in breast cancer: Src-ing for response in all the wrong kinases
Laura C. Kennedy, Vijayakrishna Gadi
Cardioprotective effects of autophagy induction in sepsis
Mahmoud Abdellatif, Simon Sedej, Frank Madeo, Guido Kroemer
Targeting properdin in the treatment of atypical haemolytic uraemic syndrome: better than eculizumab?
Kate Smith-Jackson, Kevin J. Marchbank
Microbial marauders: pancreatic microbiota and its impact on carcinogenesis
Ryan M. Thomas, Maria Zajac-Kaye
Prediction of therapeutic effects of human cardiomyocytes in myocardial infarction using non-human primates model
Hyun-Min Cho, Je-Yoel Cho
Concurrent chemoradiotherapy for stage III non-small cell lung cancer: correct clinical management as the basis to move beyond
Guilherme Jorge Costa, Carlos Gil Ferreira, Luiz Claudio Santos Thuler
The risk factors for brain metastases in patients with non-small cell lung cancer
Jun Hyeok Lim, Sang-Won Um
Inferior vena cava variation predicts fluid responsiveness during dysrhythmias: a rational rearrangement of chairs on The Titanic
Rory J. Spiegel, Michael T. McCurdy
Effect of sodium-glucose cotransporter type 2 inhibitors on liver fat in patients with type 2 diabetes: hepatic beyond cardiovascular and renal protection?
André J. Scheen
Laparoscopic Roux-en-Y gastric bypass or vertical sleeve gastrectomy: a weighty decision
Emma J. Osland, Muhammed Ashraf Memon
Understanding the link between traumatic brain injury and Alzheimer’s disease
Brandon Lucke-Wold
Novel mediators of breast cancer bone metastasis—insights from studies of gene-regulation and the global proteome
Janet E. Brown, Steven L. Wood
Patient friendly intensification of basal insulin
Sanjay Kalra
Out of darkness comes light—is there a role for light masks in treatment of diabetic macular oedema?
Mali Okada, Jay Chhablani
Cardiovascular disease in the youngest: is it time for precision prevention?
Giovanni Veronesi, Andrea M. Maresca
A pathogenic hierarchy for synovial fibroblasts in rheumatoid arthritis
Mohammed H. Abuwarwar, Konstantin Knoblich, Anne L. Fletcher
Health-related quality of life after curative-intent treatment of nonsmall cell lung cancer: can exercise lessen the burden?
Rosie Twomey, Gwyn Bebb, S. Nicole Culos-Reed
Look around your target: a new approach to early diagnosis of lung cancer
Vito R. Papapietro, Gianluca Milanese, Andrea Borghesi, Nicola Sverzellati, Mario Silva
Sphingolipid metabolism products: potential new players in the pathogenesis of bortezomib-induced neuropathic pain
Albert Alé, Andreas A. Argyriou, Jordi Bruna
Pharmacotherapy for gestational diabetes mellitus: still insulin, or what about sulfonylureas?
Angelo Maria Patti, Rosaria Vincenza Giglio, Kalliopi Pafili, Manfredi Rizzo, Nikolaos Papanas
Simulation modeling approaches to answer clinically relevant questions in breast cancer low-risk populations
Ana Calin, Miguel Martin, Sara Lopez-Tarruella
Biomarker combination is necessary for the assessment of Gaucher disease?
Pilar Giraldo, Laura López de Frutos, Jorge J. Cebolla
Cardiovascular disease in patients with rheumatoid arthritis: impact of classic and disease-specific risk factors
Giulio Cavalli, Ennio Giulio Favalli
Mid-term results of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy compared—results of the SLEEVEPASS and SM-BOSS trials
David Benaiges, Elisenda Climent, Albert Goday, Helena Julià, Juana A. Flores-Le Roux, Juan Pedro-Botet
Post-immunotherapy new onset diabetes (PINOD)—underrecognized etiology, unexplored presentation
Sanjay Kalra
Testosterone replacement in androgen insensitivity: is there an advantage?
Rafael Loch Batista, Berenice Bilharinho Mendonca
Minimally invasive surgery for early stage lung cancers: satisfactory, but we can do better
Dominique Gossot
TAILORing targeted therapies to the right patient at the right time: how close are we?
George Zarkavelis, George Pentheroudakis
Is there a relation between preserved renal function and oncological outcomes in patients undergoing partial nephrectomy for renal cell carcinoma?
Alessandro Veccia, Riccardo Autorino
Liquid biopsy in tumors: opportunities and challenges
Yi Bai, Haitao Zhao