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Editorial

To repair or to replace: four decades in the making
Patpilai Kasinpila, Y. Joseph Woo
Can pancreatitis be treated by inhibiting Ca2+ signaling?
John A. Williams, David I. Yule
The surgeon thunderbolts in 2016 lung cancer literature
Luca Bertolaccini, Alessandro Pardolesi, Jury Brandolini, Piergiorgio Solli
Inconclusive evidence to support the use of minimally-invasive radiofrequency denervation against chronic low back pain
Andreas A. Argyriou, Garifallia G. Anastopoulou, Jordi Bruna

Review Article

Tidal volume in acute respiratory distress syndrome: how best to select it
Michele Umbrello, Antonella Marino, Davide Chiumello
The 8th TNM edition for lung cancer: a critical analysis
Paul E. Van Schil, Ramon Rami-Porta, Hisao Asamura
Digital chest tomosynthesis: the 2017 updated review of an emerging application
Arianna Ferrari, Luca Bertolaccini, Piergiorgio Solli, Paola Oriana Di Salvia, David Scaradozzi
Ground glass opacities management in the lung cancer screening era
Marcello Migliore, Mariaconcetta Fornito, Manuela Palazzolo, Alessandra Criscione, Mariapia Gangemi, Francesco Borrata, Enrica Monaco, Paolo Vigneri, Marco Nardini, Joel Dunning
Esophagectomy with gastric conduit reconstruction for benign disease: extreme but important
Wei Guo, Su Yang, Hecheng Li
Making progress in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer by surpassing resistance: third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)
Giannis Mountzios
Immune checkpoint pathways in non-small cell lung cancer
Young Kwang Chae, Ayush Arya, Wade Iams, Marcello Cruz, Nisha Mohindra, Victoria Villaflor, Francis J. Giles
Treating ALK-positive non-small cell lung cancer
Dimitrios C. Ziogas, Anna Tsiara, Georgios Tsironis, Maria Lykka, Michalis Liontos, Aristotelis Bamias, Meletios-Athanasios Dimopoulos
The emerging treatment landscape of advanced non-small cell lung cancer
Panagiota Economopoulou, Giannis Mountzios
Endobronchial ultrasound-transbronchial needle aspiration (EBUS/TBNA): a diagnostic challenge for mediastinal lesions
Duilio Divisi, Gino Zaccagna, Mirko Barone, Francesca Gabriele, Roberto Crisci
Tumor progression: the neuronal input
Marco Arese, Federico Bussolino, Margherita Pergolizzi, Laura Bizzozero, Davide Pascal
Surgical approach in the oligometastatic patient
Duilio Divisi, Mirko Barone, Gino Zaccagna, Francesca Gabriele, Roberto Crisci