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Review Article

Determination of copper poisoning in Wilson’s disease using laser ablation inductively coupled plasma mass spectrometry
Sabine Weiskirchen, Philipp Kim, Ralf Weiskirchen
Wilson disease—treatment perspectives
Tomasz Litwin, Karolina Dzieżyc, Anna Członkowska
Clinical practice guidelines in Wilson disease
Chiara Saroli Palumbo, Michael L. Schilsky
Genetics and epigenetic factors of Wilson disease
Valentina Medici, Janine M. LaSalle
Cerebrospinal fluid leaks after spine tumor resection: avoidance, recognition and management
Sean M. Barber, Jared S. Fridley, Sanjay Konakondla, Jonathan Nakhla, Adetokunbo A. Oyelese, Albert E. Telfeian, Ziya L. Gokaslan
Systematic review on the utility of magnetic resonance imaging for operative management and follow-up for primary sarcoma—lessons from extremity sarcomas
Zach Pennington, A. Karim Ahmed, Ethan Cottrill, Erick M. Westbroek, Matthew L. Goodwin, Daniel M. Sciubba
Clinical features of Wilson disease
Wolfgang Stremmel, Uta Merle, Ralf Weiskirchen
Classification and differential diagnosis of Wilson’s disease
Wieland Hermann
Lactate and cancer: spinal metastases and potential therapeutic targets (part 2)
Zach Pennington, Matthew L. Goodwin, Erick M. Westbroek, Ethan Cottrill, A. Karim Ahmed, Daniel M. Sciubba
Total en bloc resection of primary and metastatic spine tumors
Elizabeth P. Howell, Theresa Williamson, Isaac Karikari, Muhammad Abd-El-Barr, Melissa Erickson, Matthew L. Goodwin, Jeremy Reynolds, Daniel M. Sciubba, C. Rory Goodwin
Clinical management of Wilson disease
Peter Hedera
Lactate and cancer: a “lactatic” perspective on spinal tumor metabolism (part 1)
Matthew L. Goodwin, Zach Pennington, Erick M. Westbroek, Ethan Cottrill, A. Karim Ahmed, Daniel M. Sciubba
Preclinical models of Wilson’s disease, why dogs are catchy alternatives
Hedwig S. Kruitwagen, Louis C. Penning
The role of endobronchial ultrasound transbronchial needle aspiration for programmed death ligand 1 testing and next generation sequencing in advanced non-small cell lung cancer
Udit Chaddha, D. Kyle Hogarth, Septimiu Murgu
Challenges in the diagnosis of Wilson disease
Aurélia Poujois, France Woimant
Current anti-copper therapies in management of Wilson disease
Isabelle Mohr, Karl Heinz Weiss
Liquid biopsy for lung cancers: an update on recent developments
Alberto E. Revelo, Alvaro Martin, Ricardo Velasquez, Prarthna Chandar Kulandaisamy, Jean Bustamante, Sevak Keshishyan, Gregory Otterson
Clinical manifestations of Wilson disease in organs other than the liver and brain
Karolina Dzieżyc-Jaworska, Tomasz Litwin, Anna Członkowska
New tools for Wilson’s disease diagnosis: exchangeable copper fraction
France Woimant, Nouzha Djebrani-Oussedik, Aurélia Poujois
Neurologic impairment in Wilson disease
Petr Dusek, Tomasz Litwin, Anna Członkowska
Placement of markers to assist minimally invasive resection of peripheral lung lesions
Ricardo Velasquez, Alvaro Martin, Mohammad Abu Hishmeh, Lawrence DeLorenzo, Samjot Singh Dhillon, Kassem Harris
Population screening and diagnostic strategies in screening family members of Wilson’s disease patients
Huamei Li, Ran Tao, Lifang Liu, Shiqiang Shang
Innovations in functional and rehabilitative knee bracing
Jim Hewlett, John Kenney
Diagnosis and management of peripheral lung nodule
Taha Khan, Yasir Usman, Tony Abdo, Fawad Chaudry, Jean I. Keddissi, Houssein A. Youness
Pros and cons of different ways to address dysfunctional autophagy in Pompe disease
Jeong-A Lim, Naresh Kumar Meena, Nina Raben
Anesthetic considerations for lung resection: preoperative assessment, intraoperative challenges and postoperative analgesia
Debra Lederman, Jasmeet Easwar, Joshua Feldman, Victoria Shapiro
Contemporary approach to the patient with malignant pleural effusion complicating lung cancer
Oleg Epelbaum, Najib M. Rahman
Molecular genetics of Pompe disease: a comprehensive overview
Paolo Peruzzo, Eleonora Pavan, Andrea Dardis

Original Article

Deep neural networks could differentiate Bethesda class III versus class IV/V/VI
Yi Zhu, Qiang Sang, Shijun Jia, Ying Wang, Timothy Deyer
Detecting insertion, substitution, and deletion errors in radiology reports using neural sequence-to-sequence models
John Zech, Jessica Forde, Joseph Titano, Deepak Kaji, Anthony Costa, Eric Karl Oermann
Machine learning for semiautomated classification of glioblastoma, brain metastasis and central nervous system lymphoma using magnetic resonance advanced imaging
Nathaniel C. Swinburne, Javin Schefflein, Yu Sakai, Eric K. Oermann, Joseph J. Titano, Iris Chen, Sayedhedayatollah Tadayon, Amit Aggarwal, Amish Doshi, Kambiz Nael
Random forest can accurately predict the development of end-stage renal disease in immunoglobulin a nephropathy patients
Xin Han, Xiaonan Zheng, Ying Wang, Xiaoru Sun, Yi Xiao, Yi Tang, Wei Qin
Tumor location is an independent prognostic factor of esophageal adenocarcinoma based on the eighth edition of TNM staging system in Chinese patients
Han-Yu Deng, Xi Zheng, Guha Alai, Gang Li, Jun Luo, Ze-Guo Zhuo, Yi-Dan Lin
Intra- and interobserver reliability of the Spinal Instability Neoplastic Score system for instability in spine metastases: a systematic review and meta-analysis
Zach Pennington, A. Karim Ahmed, Ethan Cottrill, Erick M. Westbroek, Matthew L. Goodwin, Daniel M. Sciubba
Exploring the intraoperative lung protective ventilation of different positive end-expiratory pressure levels during abdominal laparoscopic surgery with Trendelenburg position
Yun Wang, Hong Wang, Huijuan Wang, Xiao Zhao, Shitong Li, Lianhua Chen
The correlation between patient reported outcomes and biomarkers for knee osteoarthritis
Bumsup Lee, Martin Wang, Soo-Hyun Lew, Jung Jong Cho, Tae Won Kim, Nipun Sodhi, Hiba K. Anis, Michael A. Mont
Effect of chromatic contrast on stereoacuity measurement with computer-aided three-dimensional technology
Lingzhi Zhao, Huang Wu
The difference in stereoacuity testing: contour-based and random dot-based graphs at far and near distances
Lingzhi Zhao, Huang Wu
Obese patients have higher risk of breast cancer-related lymphedema than overweight patients after breast cancer: a meta-analysis
Ruxing Wu, Xiaoyuan Huang, Xiyuan Dong, Hanwang Zhang, Liang Zhuang
Ultrasound-guided preoperative single-dose erector spinae plane block provides comparable analgesia to thoracic paravertebral block following thoracotomy: a single center randomized controlled double-blind study
Bin Fang, Zhaomin Wang, Xiaojing Huang
SF3B1 mutation predicts unfavorable treatment-free survival in Chinese chronic lymphocytic leukemia patients
Yi Miao, Yi-Xin Zou, Dan-Ling Gu, Hong-Cheng Zhu, Hua-Yuan Zhu, Li Wang, Jin-Hua Liang, Yi Xia, Jia-Zhu Wu, Chun-Lin Shao, Lei Fan, Zhen Zhang, Wei Xu, Jian-Yong Li
Clinical outcomes after absorbable suture fixation of patellar osteochondral fracture following patellar dislocation
Zu-Xi Li, Huang-He Song, Qing Wang, Dun-Ming Guo
Effects of sub-chronic, low-dose cadmium exposure on kidney damage and potential mechanisms
Qiling Liu, Rongqiang Zhang, Xiang Wang, Xiangli Shen, Peili Wang, Na Sun, Xiangwen Li, Xinhui Li, Chunxu Hai
The relationship between preliminary efficacy and prognosis after first-line EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment of advanced non-small cell lung cancer
Dongfang Chen, Tianqing Chu, Qing Chang, Yanwei Zhang, Liwen Xiong, Rong Qiao, Jiajun Teng, Baohui Han, Runbo Zhong
Astym® therapy improves FOTO® outcomes for patients with musculoskeletal disorders: an observational study
Leah S. Harris, Suzanne Freeman, Ying-Chih Wang
Long non-coding RNA IQCJ-SCHIP1 antisense RNA 1 is downregulated in colorectal cancer and inhibits cell proliferation
Jia Zhang, Zehua Bian, Guoying Jin, Yuhang Liu, Min Li, Surui Yao, Jing Zhao, Yuyang Feng, Xue Wang, Yuan Yin, Bojian Fei, Xiaofeng Han, Zhaohui Huang
Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts
Guochun Zhang, Yulei Wang, Bo Chen, Liping Guo, Li Cao, Chongyang Ren, Lingzhu Wen, Kai Li, Minghan Jia, Cheukfai Li, Hsiaopei Mok, Xiaoqing Chen, Guangnan Wei, Jiali Lin, Zhou Zhang, Ting Hou, Han Han-Zhang, Chenglin Liu, Hao Liu, Jing Liu, Charles M. Balch, Funda Meric-Bernstam, Ning Liao
Dexmedetomidine versus midazolam and propofol for sedation in critically ill patients: Mining the Medical Information Mart for Intensive Care data
Yiyan Song, Shaowei Gao, Wulin Tan, Zeting Qiu, Huaqiang Zhou, Yue Zhao

Case Report

Management of presacral schwannomas—a 10-year multi-institutional series
Zach Pennington, Clemens Reinshagen, A. Karim Ahmed, Sean Barber, Matthew L. Goodwin, Ziya Gokaslan, Daniel M. Sciubba
Difficulties in diagnosis and treatment of Wilson disease—a case series of five patients
Anna Członkowska, Karolina Dzieżyc-Jaworska, Bożena Kłysz, Rędzia-Ogrodnik Barbara, Tomasz Litwin
First-line application of apatinib combined with S-1 based on peripheral circulating tumor cell screening to treat advanced gastric adenocarcinoma: a case report
Weikai Chen, Jianping Yu, Yanan Zhang, Wenjie Wang, Wenwen Yu, Xin Shi, Zipeng Xu, Hongbin Liu
Acute exacerbation of interstitial lung disease after radical surgery for lung cancer: a case report
Manni Zhu, Chaojie Wu, Zhenzhen Wu, Guangming Ren, Ningfei Ji, Mingshun Zhang, Mao Huang
The interesting case—orphan diseases—double trouble
Ulrike Reuner, Wolfgang Stremmel, Ralf Weiskirchen
A case of pseudomembranous tracheitis caused by Mycoplasma pneumoniae in an immunocompetent patient
Yong Hoon Lee, Hyewon Seo, Seung Ick Cha, Chang Ho Kim, Jaehee Lee
Aggressive mycobacterium abscessus on repeated exogenous lipoid pneumonia in the right middle lobe
Bo Mi Gil, Myung Hee Chung, Young-Du Kim, Yong Hyun Kim, Hye Seon Kang, Il Jung Kim

Surgical Technique

Extracorporeal radiation and reimplantation: a safe and viable option for reconstruction after sacral tumor resection?
Matthew L. Goodwin, Manit K. Gundavda, Rajeev Reddy, Kedar Deogaonkar, Murad Lala, Amresh Baliarsing, Daniel M. Sciubba, Kevin B. Jones, Manish Agarwal

Editorial Commentary

A deeper understanding of the tumor microenvironment in pancreatic cancer: the key to developing effective immunotherapies
Patrick W. Underwood, Jose G. Trevino
Is bilateral radiation an option for BRCA mutation carriers with unilateral breast cancer?
Steven A. Narod
Does alfacalcidol reduce cardiovascular complications in hemodialysis patients?
Louis-Charles Desbiens, Fabrice Mac-Way
Inflammatory lymphadenopathies predicting renal cell carcinoma prognosis: association not so convincing yet
Rizwan Ishtiaq, Zubair Khan
Which role for renal tumor ablation and which factors can influence long-term oncologic outcomes?
Roberto Iezzi, Riccardo Manfredi
VCAM-1+ macrophage subset as ‘educators’ in fetal liver for transition to definitive hematopoiesis
Pranela Rameshwar
Beyond the predictors of lymph node metastases in patients undergoing lymph node dissection for renal cell carcinoma: the impact of tumour side and location
Riccardo Campi, Francesco Sessa, Andrea Mari, Marco Carini, Sergio Serni, Andrea Minervini
Identification of the right cell sources for the production of therapeutically active extracellular vesicles in ischemic stroke
Bernd Giebel, Dirk M. Hermann
Glucocorticoids: novel agents to stimulate beta-cell neogenesis?
Mark A. Russell, Pia Leete
Early-stage non-small cell lung cancer: the required type of resection (lobar vs. sublobar) remains unanswered
Natalie Baldes, Michael Eberlein, Servet Bölükbas
SELECTing adjuvant treatment in early stage epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer
Fabrizio Tabbò, Maria Lucia Reale, Enrico Ruffini, Silvia Novello, Francesco Guerrera
Metachronous renal cell carcinoma: An unbeatable leviathan?
Alessandro Antonelli, Alessandro Veccia, Riccardo Autorino
Inflammatory lymphadenopathy in renal cell carcinoma: prognostic tool?
Purnima Malhotra, Hemant Goel, Ashwani Kumar Mishra
Immunotherapy for head and neck cancer: where are we now and where are we going?
Joshua M. Bauml, Charu Aggarwal, Roger B. Cohen
Combining immunotherapy and epidermal growth factor receptor kinase inhibitors: worth the risk?
Hira Latif, Stephen V. Liu
Renal function after kidney surgery: “it’s tough to make predictions, especially about the future”
John M. DiBianco, Patrick T. Gomella, Mark W. Ball
A novel macrophage subtype directs hematopoietic stem cell homing and retention
Marcin Wysoczynski, Joseph B. Moore IV, Shizuka Uchida
Depth of invasion for prognostic stratification in oral cavity cancer: do we need further validation?
Cesare Piazza, Lorenzo Bresciani, Lorenzo Giannini
Coupled biosynthesis of cordycepin and pentostatin in Cordyceps militaris: implications for fungal biology and medicinal natural products
Peter A. D. Wellham, Dong-Hyun Kim, Matthias Brock, Cornelia H. de Moor
Editorial commentary: the multiligament injured knee: current controversies and strategies for improving outcomes
Adnan Saithna
Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis
Xiaobo Zhu, Kaijia Zhang, Ke Lu, Tianshu Shi, Siyu Shen, Xingren Chen, Jian Dong, Wang Gong, Zhengyuan Bao, Yong Shi, Yuze Ma, Huajian Teng, Qing Jiang
Post-traumatic osteoarthritis (PTOA) animal model to understand pathophysiology of osteoarthritis
Quante Singleton, Santul Bapat, Sadanand Fulzele
Brain metastases in EGFR-positive non-small cell lung cancer: the way to the sanctuary becomes less winding
Antonio Passaro, Letizia Gianoncelli, Valeria Stati, Filippo de Marinis
Asymmetric dimethylarginine, erythropoietin resistance, and anemia in CKD
Tammy L. Sirich, Glenn M. Chertow
Current landscape of cytoreductive nephrectomy: who, when, and why?
Jiping Zeng, Alfredo Harb De la Rosa, Juan Chipollini
Reactive astrocytes foster brain metastases via STAT3 signaling
Braden C. McFarland, Etty N. Benveniste
New insights into cordycepin production in Cordyceps militaris and applications
Sunita Chamyuang, Amorn Owatworakit, Yoichi Honda
The role of acute kidney injury duration in clinical practice
Chyi-Sheng Khor, Wei-Jie Wang