Article Abstract

The PLAN score can predict poor outcomes of intracerebral hemorrhage

Authors: Wanliang Du, Xingquan Zhao, Yilong Wang, Guitao Zhang, Jiming Fang, Yuesong Pan, Liping Liu, Kehui Dong, Gaifen Liu, Yongjun Wang, on behalf of the China National Stroke Registry (CNSR) Investigators

Abstract

Background: For patients hospitalized after acute ischemic stroke (AIS), the preadmission comorbidities, level of consciousness (LOC), age and neurologic deficit (PLAN) score can help to identify those who may have a poor outcome. Implementing the PLAN score in other types of stroke may also have predictive value. Our study aimed to evaluate the PLAN score’s prognostic accuracy in predicting 1-year mortality and severe disability after intracerebral hemorrhage (ICH).
Methods: We analyzed data found in the China National Stroke Registry (CNSR) of 2,453 hospitalized patients in 132 urban Chinese hospitals, diagnosed with ICH from September 2007 to August 2008. The outcomes analysis included 30-day mortality, modified Rankin Scale score (mRS) of 5–6 at discharge, and 1-year mortality. Univariate and multivariate analysis was performed, and we calculated consistency statistics (C statistic). We evaluated the PLAN score performance using area under the curve (AUC) calculations.
Results: We found that the 30-day mortality was 12.6%, the frequency of a mRS 5–6 at discharge was 20.6%, and 1-year mortality was 21.9%. The PLAN score had good predictive value in 30-day mortality (C statistic, 0.82), death or severe dependence at discharge (0.84), and 1-year mortality (0.82).
Conclusions: In patients hospitalized for ICH, the 30-day mortality, death or severe dependence at discharge and 1-year mortality can be predicted by the PLAN score. Similarly to patients hospitalized after AIS, the PLAN score can help to identify patients likely to have poor outcomes following hospitalization for ICH.