Can stem cell therapy increase the rate of myocardial recovery in left ventricular assist device-supported advanced heart failure patients?—current data and future perspectives

Despite advances in medical management and left ventricular assist device (LVAD) technology, advanced chronic heart failure still represents a debilitating disorder with poor prognosis and high mortality rates (1). However, despite this, in selected patients with advanced chronic heart failure, myocardial structure and function can improve either spontaneusly or as a result of different therapeutic interventions.