Article Abstract

Circular RNAs as diagnostic tool for renal transplant patients with acute rejection

Authors: Joseph B. Moore IV, Michael L. Merchant, Shizuka Uchida

Abstract

The kidney is a multifunctional organ that filters waste products from the blood in our body in the form of urine. In addition, kidneys also function to regulate blood pressure, balance electrolytes, and secrete erythropoietin to support erythrocyte (red blood cells) production. Severe loss of kidney function or kidney failure results in the accumulation of fluid and metabolic waste products—if left untreated, can lead to seizures, coma, or even death.

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