Immunohistochemistry as a tool for screening rare renal cancers

Cissy Yong, Grant D. Stewart, Christian Frezza

Abstract

Recent additions of succinate dehydrogenase (SDH) and hereditary leiomyomatosis and renal cell cancer (HLRCC, associated) fumarate hydratase (FH)-deficient renal cell carcinomas (RCC) to the 2016 WHO Classification of Renal Tumours (1) have highlighted an evolving need for the distinction between renal cancer subtypes.