Promotion of synaptogenesis and neural circuit development by exosomes

Jun Yamada, Shozo Jinno


Various mediators, such as neurotransmitters, gap junctions, cytokines, cell adhesion molecules, and growth factors, are involved in cell-to-cell communication in the brain (1). In particular, extracellular vesicles (EVs) have recently attracted interest as a novel type of intercellular communication mediator under physiological and pathological conditions (2).