Promotion of synaptogenesis and neural circuit development by exosomes

Various mediators, such as neurotransmitters, gap junctions, cytokines, cell adhesion molecules, and growth factors, are involved in cell-to-cell communication in the brain (1). In particular, extracellular vesicles (EVs) have recently attracted interest as a novel type of intercellular communication mediator under physiological and pathological conditions (2).