Managing intrinsic pro-degradatory mechanical and cellular cycles in the development of osteochondral lesions

Seok Jung Kim, Asode Ananthram Shetty, Saif Ahmed, Neha Shetty, Sang Heon Lee


It is an aim of medical scientists to reverse disease. Chondral lesions that classically develop and super-specialised tissues have been the focus of many efforts in regenerative medicine to restore a biomechanically efficient, responsive, and self-sustaining equilibrium at the joint surface.