The interesting case—orphan diseases—double trouble

Ulrike Reuner, Wolfgang Stremmel, Ralf Weiskirchen


With an incidence of 1:20,000–1:30,000, Wilson’s disease is regarded as a rare disease. Yet rarer, however, is the co-occurrence of two unrelated orphan diseases in the same patient. By means of two case reports, we would like to illustrate the necessity of an appropriate differential diagnostic evaluation and treatment of these disorders.